Nano-Biomimetics

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Nano-Biomimetics

• Team ?

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Nano-biomimetics?

• What is nano-biomimetics?
• Biological self-assembly
• Viral assembly
• Gecko Feet

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What is nano-biomimetics?

• Utilizes biological mechanisms to create
  materials
• Mimicking biological self-assembly processes
• Using single biological units as a building block
  along with inorganic materials
• Mimics biology at the molecular level
• Synthesizing structures that mimic biological
  structures

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Utilizing biological mechanisms

• Atom-precise manipulation yields composite
  materials and nano-scale structures with
  desirable properties
• Parallel self-assembly processes achieve
  precision with high speed and reproducibility

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Biological self-assembly

• Bottom-up fabrication process
• Continuing miniaturization of devices in
  nanotechnology
• Nature already assembles its smallest components
  into ordered structures

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Biological self-assembly applications

• Genetically Engineered Proteins for Inorganics
  (GEPIs)
• Methods
• Biopatterning
• Neuron growth on patterned substrates

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Biological self-assembly applications
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Viral assembly biology

• Abalone shell mostly chalk, but 3000x stronger
  because of crystal structure
• Very difficult to assemble crystals, requires
  precise control in 3-D

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Viral assembly biomimetic

• Genetically engineered virus attaches to molecule
  of building material
• Viruses orient themselves in solution, producing
  well-ordered liquid crystal

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Viral assembly applications

• Procedure can easily scale up
• Multiple applications
• Better materials

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Mimicking biological structures

• Top-down approach using lithography, scanning
  probes, CVD, sputter coating, and many other
  techniques normally unassociated with biology
• Requires very precise manipulation

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Gecko feet biology

• Millions of hairs called setae
• Fiber radius is nanometer-scale
• Adhesion due to van der Waals and capillary forces

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Gecko feet biomimetic

• Use electron beam lithography and dry etching to
  create synthetic polymer hairs
• Attach to flexible base
• Palm-sized piece can support a human

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Gecko feet applications
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Nano-biomimetics!

• Create materials with novel properties
• Synthesize existing bio-materials in larger
  quantities
• Integrate biomolecules and materials with
  inorganic ones for hybrid systems

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References

• Bio-assembly
• Sarikaya, Mehmet. "Moleucular biomimetics
  nanotechnology through biology. Nature Materials
  Sept. 2003.
• Gyorvary, Erika S. "Biomimetic Nannostructure
  Fabrication Nanolithographic Lateral Patterning
  and Self-Assembly of Functional Bacterial
  S-Layers at Silicon Supports." 11 Dec. 2002. Nano
  Letters. Vol. 3. 2004. 315
• Zhang, Shuguang. "Fabrication of novel
  biomaterials through molecular self-assembly."
  Nature biotechnology Oct. 2003.
• Quinion, Michael. "Turns of Phrase Biomimetics."
  World Wide Words. 22 Nov. 1997.
  lthttp//www.worldwidewords.orggt.
• Viral Assembly
• http//www.sunlandimports.com
• http//www.sciencemag.org/cgi/content/full/296/556
  9/892
• http//www.pnas.org/cgi/content/full/100/12/6946
• http//web.mit.edu/giving/spectrum/fall05/building
  _on_nature.html
• http//pubs.acs.org/cgi-bin/sample.cgi/nalefd/2004
  /4/i01/html/nl0347536.html
• Gecko foot
• http//www.andrew.cmu.edu/user/gshah/Project_model
  ing.htm
• http//photos.wildmadagascar.org/images/uroplatus_
  fimbriatus-0143.shtml
• http//www.houstonvoice.com/2004/6-18/view/actiona
  lert/action.cfm
• http//onnes.ph.man.ac.uk/nano/Publications/Nature
  mat_2003.pdf
• Spiderman http//spiderman.sonypictures.com