STRIATED SKELETAL MUSCULAR TISSUE

1
STRIATED SKELETALMUSCULAR TISSUE
2
FUNCTIONS

• Movement
• Heat
• Stabilization

3
TYPES

• Striated Skeletal
• Voluntary
• Striated Cardiac
• Involuntary
• Visceral Smooth
• Involuntary

4
PROPERTIES

• Contractibility
• Excitability
• Extensibility
• Elasticity

5
FASCIA

• Tendon of Origination
• Epimysium
• Perimysium
• Endomysium
• Tendon of Insertion

6
MYOFIBER STRUCTURE

• Sarcolemma
• Sarcoplasm
• Sarcoplasmic Reticulum
• Transverse Tubule
• Triad
• T Tubule
• Terminal Cisterna
• Multinuclear
• Mitochondria
• Myofibrils

7
MYOFIBER MYOFILAMENTS

• Contractile Proteins
• Actin
• Myosin
• Regulatory Proteins
• Troponin
• Tropomyosin
• Structural Proteins
• Titin
• Nebulin
• Myomesin
• Dystrophin

8
SARCOMERIC AREAS

• Z Disc
• I Band
• A Band
• H Zone
• M Line
• I Band
• Z Disc

9
METABOLISM OF MYOFIBER

• Anaerobic Respiration
• Glycolysis
• 2 ATPs / Glucose
• 2 Trioses / Glucose
• 2 NADH2 / Glucose

10
AEROBIC RESPIRATION

• Transition Reaction
• 2 Pyruvic Acid / Glucose
• 2 NADH2 / Glucose
• Citric Acid Cycle
• 2 ATPs
• 2 FADH2 / Glucose
• 6 NADH2 / Glucose
• Electron Chain Transport

11
BLOOD SUPPLY

• Myofiber
• Capillary
• Arterial
• Venous

12
NEUROMUSCULAR JUNCTION

• Somatic Motor Neuron
• Dendrites
• Cell Body
• Axonic Hillock
• Teleodendria
• Synaptic End Bulb
• Synaptic Vacuole
• Exocytosis
• ACH
• Synapsis
• Diffusion

13
NEUROMUSCULAR JUNCTION

• Myofiber
• Sarcolemma
• Ach Receptor
• Transverse Tubule
• Na Gates Open
• Na Influx
• Transverse Tubule
• Triad

14
NEUROMUSCULAR JUNCTION

• Myofiber
• Triad
• Terminal Cisternae
• Ca2 Gates Open
• Ca2 Sarcoplasmic Diffusion
• Activated Troponin
• Activated Tropomyosin
• Troponin Tropomyosin Complex
• Exposed Actin

15
NEUROMUSCULAR JUNCTION

• Myofiber
• Ca2 Sarcoplasmic Diffusion
• Myosin Cross Bridges
• ATP Myosinases
• Dephosphorylation of ATP
• Diphosphate Bonds Broken
• Energy Released
• ADP and Free High Energy

16
NEUROMUSCULAR JUNCTION

• Myofiber
• Actin-Myosin Lock Up
• Myomesin Pulls on Myosin
• Myosin Pulls Actin
• Myosin and Actin in H Zone
• H Zone Disappears
• Sarcomere Shortens
• Z Disc
• All Sarcomeres Shorten

17
NEUROMUSCULAR JUNCTION

• Myofiber
• Dystrophin
• Sarcolemma
• Endomesium
• Perimesium
• Epimesium
• Tendon of Insertion

18
NEUROMUSCULAR JUNCTION

• Remove Threshold Stimulus
• Na1 Gates Close
• K1 Gates Open
• Repolarization
• Refractory
• AChE
• Actin-Myosin unlock
• Troponin-Tropomyosin Complex unlock

19
NEUROMUSCULAR JUNCTION

• Remove Threshold Stimulus
• H Zone Reappears
• Sarcomeres Return
• Ca2 Transported to Organelle of Storage
• Calsequestrin
• Ca2 Gates Closed
• Expenditure of Energy

20
MOTOR UNIT

• One Somatic Motor Neuron
• 150 Myofilbers
• Epimesium
• Tendon of Insertion

21
TWITCH CONTRACTION

• Response to One Stimulus
• Latent Period
• Contraction Period
• Summation Period
• Refractory Period
• Relaxation Period

22
APPLICATION OF STIMULI

• Treppe
• Complete Tetanic
• Incomplete Tetanic
• Wave Summation
• Smooth Summation
• Rough Summation

23
MUSCULAR TONUS

• Partial Contraction
• Involuntary Contraction

24
TYPES OF MOVEMENTS

• Isotonic
• Examples
• Isometric
• Examples

25
TYPES OF MUSCLES

• Red Muscles
• Myoglobin
• Slow
• Examples
• White Muscles
• Myoglobin
• Fast
• Examples

26
TYPES OF MUSCLES

• Red and White Mixture
• of Myoglobin
• Examples