Title: Nessun titolo diapositiva
1(No Transcript)
2(No Transcript)
3(No Transcript)
4(No Transcript)
5Per ordine alfabetico
6NLM DATABASES
- Consumer Health Databases ClinicalTrials.gov ,
MEDLINEplus - Databases about AIDS AIDS Information Resources ,
AIDSLINE , AIDSTRIALS and AIDSDRUGS - Databases about Chemicals and Toxicology Chemical
Carcinogenesis Research Information System ,
ChemID , ChemIDplus , Developmental and
Reproductive Toxicology Database , EMIC ,
Gene-Tox Program of the U.S. Environmental
Protection Agency , Integrated Risk Information
System , Toxic Chemical Release Inventory ,
Toxicology Data Network , TEHIP , TOXLINE - Databases about Genetics Human Genome Resources ,
Entrez Molecular Sequence Database System ,
GenBank Retrieval and Sequence Similarity
Searching by Internet Electronic Mail, Nat'l
Center for Biotechnology Information , Submitting
Data to GenBank - Databases about Health Services Research ,
HealthSTAR (incorporates Health Planning
Administration and HSTAR Databases), Health
Services Research Projects in Progress , Health
Services/Technology Assessment Texts (HSTAT) - NLM Image Databases , Images from the History of
Medicine on Internet , Visible Human Project - Other Specific NLM Databases DIRLINE , DOCLINE ,
HISTLINE , SERHOLD
7Fetal growth
8Clinicaltrials.gov
- Per chi pazienti e familiari, media ma anche
medici - Quali informazioni abstract dei protocolli
(obiettivi, stato di reclutamento, criteri per
reclutamento e partecipazione, contact info),
informazioni aggiuntive (study design, fase del
trial, malattia in studio) - Quando è stato fatto in seguito a atto dellFDA
del 1997 ? registro degli studi finanziati da NIH
e enti privati su trattamento sperimentale della
malattie gravi e/o con rischio di vita - Status non richiede registrazione. Recensisce
oltre 5200 studi sponsorizzati da NIH. Studi
sponsorizzati da industria privata saranno
aggiunti nel 2000-2001.
9(No Transcript)
10(No Transcript)
11(No Transcript)
12(No Transcript)
13(No Transcript)
14(No Transcript)
15(No Transcript)
16Descrive in maniera schematica i dettagli dello
studio
17Criteri di inclusione ed esclusione
18(No Transcript)
19(No Transcript)
20Premesse e razionale
21(No Transcript)
22Clinical trials Resource information
- Understanding clinical trials
- Informations about specific types of clinical
trials (cancer trials, vision research..) - NIH Clinical Alerts
- Information about drugs (recently approved,
electronic orange book) - General health information (Medline plus, FDA
consumer magazine, NIH health info) - Related information
23(No Transcript)
24(No Transcript)
25(No Transcript)
26Trial interrotto per chiara dimostrazione di
inefficacia
27Suggerimento clinico
28Farmaci di recente approvazione
29Farmaci di recente approvazione
30Farmaci di recente approvazione scheda tecnica
31(No Transcript)
32(No Transcript)
33(No Transcript)
34(No Transcript)
35(No Transcript)
36(No Transcript)
37(No Transcript)
38(No Transcript)
39(No Transcript)
40About HSDB HSDB contains over 4500 chemical
records, each of which can have as many as 150 or
so fields of data. HSDB's road scope covers
human and animal toxicity, safety and handling,
environmental fate, and more. HSDB data
undergoes a high level of peer review by the HSDB
Scientific Review Panel. HSDB contains one
record per chemical.
41(No Transcript)
42(No Transcript)
43(No Transcript)
44(No Transcript)
45Dati dellEPA su human risk assessment, focus su
dose response
46(No Transcript)
47CCRIS dati di carcinogenesi, mutagenesi, e
inibizione della crescita tumorale dal NCI
Chemical Carcinogenesis Research Information
48(No Transcript)
49About GENE-TOX GENE-TOX is created by the U.S.
Environmental Protection Agency (EPA) and
contains genetic toxicology (mutagenicity) test
data, resulting from expert peer review of the
open scientific literature, on some 3000
chemicals. The GENE-TOX program was established
to select assay systems for evaluation, review
data in the scientific literature, and recommend
proper testing protocols and evaluation
procedures for these systems. Each of TOXNET's
toxicology data files (HSDB, IRIS, CCRIS, and
GENE-TOX) contains one record per chemical.
50GENE-TOX dati di genotossicità sottoposti a peer
review dallEPA
51(No Transcript)
52Database di letteratura tossicologica
TOXLINE database mirato su efetti biochimici,
farmacologici, fisiologici e tossicologici di
farmaci e composti chimici EMIC Environmental
Mutagen Information Center letteratura corrente
su agenti testati per attività genotossica DART/ET
IC Developmental and Reproductive Toxicology and
Environmental Teratology Information Center dati
di tossicologia della riproduzione e dello
sviluppo
53About DART The Developmental and Reproductive
Toxicology (DART) database consists of citations
to literature on chemical, physical, and
biological agents that may cause birth defects.
It contains citations to literature published
since 1989. Approximately 60 percent of DART is
derived from MEDLINE.
54Database di interesse ambientale
TRI Toxic Release Information report dallanno
1995 dallEPA sul rilascio ambientale di sostanze
tossiche
55Database di Informazione Chimica e Biochimica
ChemIDplus informazioni su sinonimi, struttura e
link ad altri database contenenti informazioni su
sostanze chimiche e farmaci HSDB Structures
informazioni sulla struttura bidimensionale dei
composti presenti nel data base HSDB (hazardous
Substances DB) NCI-3D informazioni sulla
struttura 2D e 3D a cura del National Cancer
Institute