Pravastatin PowerPoint PPT Presentations

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A-1. A-1. Introduction. Pravastatin-Aspirin. 7asdf. Fred T. Fiedorek, M.D. Vice President, Clinical Design & Evaluation, Metabolics. Pharmaceutical Research Institute ...

Donald A. Berry, PhD. Professor and Chair of Biostatistics, University of Texas, ... Lawrence J. Dacey, MD. Associate Professor of Surgery, Dartmouth ...

Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) ... Randomized to pravastatin 40 mg/d or placebo. Baseline TC 155 348 mg/dL ...

Women. African-Americans. Type 2 Diabetes. Major Subgroups (post ... Differences between event curves. log-rank tests & Cox proportional. hazards (PH) model ...

To determine whether pravastatin reduces morbidity and mortality in elderly men ... Shepherd J, Blauw GJ, Murphy MB et al. on behalf of the PROSPER study group. ...

Prospective Pravastatin Pooling Project: Coronary Event Rates in CARE and LIPID ... Placebo Diabetic. Pravastatin Nondiabetic. Pravastatin Diabetic. Placebo ...

LIPID: Long-term Intervention with Pravastatin in Ischemic Disease. Purpose ... 9014 patients with AMI or hospitalization 3 36 months previously for unstable ...

PROVE IT: Pravastatin or Atorvastatin Evaluation and Infection Therapy - TRIAL DESIGN ... Prior statin therapy (%) Index event (%) Unstable angina. MI without ...

Both pravastatin and aspirin are indicated for secondary prevention The pravastatin-aspirin ... 325, 500 Bufferin 4 81, 325, 500 Adprin 1 325 Alka-Seltzer 3 ...

... atorvastatin pravastatin fluvastatin lovastatin sa etak le enja angine pektoris 1. le iti uzrok 2. izbegavati faktore rizika 3. nitroglicerol 4.

PROSPER: trial design Shepherd J et al. Lancet. 2002;360:1623-30 PROSPER: Baseline Clinical Characteristics Placebo Pravastatin Age (yrs) 75.3 75.4 Female (%) 52 52 ...

Pitavastatin. Pravastatin. Rosuvastatin. Simvastatin. Brand. Lipitor. Lescol. Mevacor. Livalo. Pravachol. Crestor. Zocor. LDL ...

Approach to Dyslipidemia Dr Zuhair M Shawagfeh FRCPI ... pravastatin or rosuvastatin Less drug interactions: pravastatin, fluvastatin, rosuvastatin ...

Pravastatin. Placebo. Yr. n=269. n=206. CARE: Fatal CHD or Nonfatal MI (Primary End Point) ... Pravastatin 1,441 1,357 1,285 1,228 1,177 294 65 yr. 65 yr ...

Intensive Statin Therapy A Sea Change. in ... Pravastatin 40 mg. Equivalent doses. Trial was designed to demonstrate non-inferiority of pravastatin. ...

CHD death reduced by pravastatin in CARE and LIPID trial without DM P't and only ... in the reduction of CHD events with pravastatin below and above BMI 27 ...

LDL 130 md/dL despite the use of pravastatin, 20 mg/day ... To continued pravastatin, 20 mg/day, and the same HAART to start EZB, 10 mg ...

An Intervention Trial Evaluating ... (2.4) 0.01 0.25 0.5 1.0 2 4 WOSCOPS Pravastatine HPS Simvastatin e ASCOT-LLA Atorvastatine JUPITER Rosuvastatine PROVE-IT ...

lovastatin (Mevachor and generic) - pravastatin (Pravachol and generic) - rosuvastatin (Crestor) ... simvastatin (Zocor and generic) CDA CPG *Expert Committee. ...

Statin Rosuvastain (Crestor ) A potent HMG-CoA reductase inhibitor ... Pravastatin (Mevalotin ), Rosuvastatin (Crestor ) Lovastatin (Mevacor ), Simvastatin (Zocor ...

AHA 2000, Late breaking clinical trials presentation. The PROVE IT (Pravastatin or Atorvastatin Evaluation and Infection Therapy) trial is a head-to-head trial, ...

... and CYPs OATP1B1 4.5 Pitavastatin CYP3A4/OATP1B1 7.0 Atorvastatin OATP1B1 8.0 Pravastatin CYP3A4 8.0 Simvastatin Presumed Mechanism AUC or Cmax Increase In ...

Prescriptions (in millions) 315. 52. 381. 145. Adverse events (n) Atorvastatin. Pravastatin. Simvastatin. Rosuvastatin. Outcome ...

40mg of Pravastatin (Pravachol) or 80mg of Atorvastatin (Lipitor) ... More side effects with Atorvastatin. Future studies pending. Summary ...

Ontario Program for Optimal Therapeutics, Guidelines for Stable Ischemic Heart ... (ACS): atorvastatin; in setting of post-ACS: pravastatin or simvastatin ...

... clofibrate 1961 lovastatin 1979 gemfibrozil 1969 compactin 1974 pravastatin 1980 cerivastatin 1988 simvastatin 1980 fluvastatin 1982 Chronology of Cholesterol ...

They have short half-lives (~2 hours except atorvastatin at 14h) but effective ... 4162 patients within 10 days of an ACS were randomized to pravastatin 40mg/d or ...

Indicator: implementation of personalised care plans and the care planning ... Proportion of statins prescribed as simvastatin or pravastatin. Medicines Management 2 ...

Systematic (or introduced) error that leads to data distortion (skewing) and ... Concomitant ingestion of food- antibiotics. Diurnal variation- pravastatin, prednisone ...

Meta-analysis of. Effect of Statin Treatment. on Risk of ... Pravastatin. 20. 1.9. 2138. 2133. 60.0. 86. 11.9. 13.6. 36.5. 100 -9.8. LIEM. 2002. NL. Secondary ...

Title: No Slide Title Author: karim Last modified by: Jamil Mayet Created Date: 10/16/1999 7:20:55 AM Document presentation format: On-screen Show Company

... LIPID and CARE Relative Risk Reduction Cox Proportional Hazards LIPID and CARE Meta-Analysis Models Model 2 Hierarchical, Random Effects Model 2 ...

Title: The PROVE IT Trial Author: shedges Last modified by: cbellinger Created Date: 7/2/2004 1:38:10 PM Document presentation format: On-screen Show

HIGH SENSITIVITY C-REACTIVE PROTEIN IN CARDIOVASCULAR DISEASE AND MORTALITY Gary A. Lopez, M.D. Makati Medical Center Asian Hospital and Medical Center

Multicenter, randomized, double-blind, active- controlled trial ... adverse events were constipation, flatulence, dyspepsia and abdominal pain, ...

Taking the Lead New advances in cholesterol management Hervey Wilcox Consultant Chemical Pathologist Epsom and St Helier NHS Trust

The American Heart Association. Scientific Session 2005. Presented by Dr. Haruo Nakamura ... of coronary heart disease events compared with diet modification alone at ...

Title: Bez nadpisu Author: 3. LF UK Last modified by: 3. LF UK Created Date: 11/6/2003 5:38:59 PM Document presentation format: p edv d n na obrazovce

Reversal of Atherosclerosis with Aggressive Lipid Lowering REVERSAL

Title: Schach dem Herzinfarkt Subject: Herzwoche 1999, Kleve Author: Dr. Harald Mei en Last modified by: HM2 Created Date: 11/5/1999 6:59:09 PM Document presentation ...

What percentage of your patients with dyslipidemia who are receiving statin therapy alone achieve their ... Rosuvastatin 20 mg + niacin ER 1 g Simvastatin 40 ...

This shows data from the STELLAR trial comparing rosuvastatin, atorvastatin, ... 16% 55% Increase in treatment of dyslipidemia: ...

Slide 1 ... Hipolipemici

Slide 1 ... Hipolipemici

... Effects Concomitant Use of Meds Verapamil, Amiodarone Nefazadone HIV protease inhibitors Macrolide antibiotics Antifungal azoles** Cyclosporine Nicotinic ...

Reste-t-il des patients risque vasculaire qu'il ne faut pas encore traiter par ... Ce qui est acquis. Pr vention secondaire chez le coronarien (4S, CARE, ...

Dyslipidemia in the Metabolic Syndrome: Can 1 agent treat all? Brian Tulloch, M.D. Diagnostic Clinic Houston, Texas

Biochemistry Problem Set Jack Blazyk 3/9/04

Necessity of MD involvement. Adherence to drug treatment. Clinical cardiovascular benefit ... NECESSITY OF PHYSICIAN INVOLVEMENT. PREDICT. Study Drug ...

OATP1B1: benzylpenicillin, atorvastatin,cerivastatin, fluvastatin, pitavastatin, ... MATE -1. Expression of Various Renal Transporters in Human Kidney ...

A philosophical niche, calculation very hard. ... Possible Calculation. Simulate a from the beta(14,5) Simulate an x from binomial(17, ...

Atorvastatin is Widely Prescribed. Atorvastatin has been approved in over 50 countries ... atorvastatin: myalgia (3%) simvastatin: athralgia (7%) and chest pain (4 ...

ASCOT Lancet, April 2003 n=10,305. Evidence for: primary prevention of CHD and ... safety and efficacy of titrating dose to attain targets & magnitude ...

Experimental Studies Dr Amna Rehana Siddiqui Assistant Professor Department of Community and Family Medicine

Historique des remboursements Quels usages d velopper chez les m decins ? Historique des remboursements : Quels usages d velopper ? Un noyau dur d ...