Title: Title Slide IBD
1Title Slide - IBD
2Pathophysiology of IBD - pt. 1
3Pathophysiology of IBD - pt. 2
4Pathophysiology of IBD - pt. 3
5Psychosocial Factors are Widely Believed to Play
a Role in IBD
6Stress Does Not Predict IBD Activity 1-3 Months
Later
7Stress Enhances Intestinal Inflammationin a
Murine Model
8Perceived Stress is Associated with Rectal
Inflammation in Asymptomatic UC
9Long-term Perceived Stress Raises the Risk of
Exacerbation in UC
10High Long-term Stress Triples the 8-Month Risk of
Exacerbation in UC
11Circulating Stress Mediators
12Stress Increases Intestinal Permeability
13Effects of Stress on the Immune System
14Stress, Immunity, and Chronic Inflammation
15Effects of Social Stress on the Gut Flora of
Young Monkeys
16Stress Hormones and Gut Bacteria
17Stress Mediators in the Gut
18How Stress Affects Animal Colitis
19Stress and IBD Possible Behavioral and
Psychological Mediators
20Pathophysiology of IBD - Summary
21Pathophysiology of IBD - Summary
22Psychosocial Factors and IBDPossible Points of
Impact
23Psychosocial / Nonpsychosocial Factors Insecure
Attachment and p-ANCA in UC
24Personality in IBD Older Concepts
25Personality in IBD, a Prospective Study
26Characteristic Personality Traits Might Be
Effects of IBD
27Generic Quality of Life in IBD
28Generic Quality of Life in IBD Sickness Impact
Profile Subscales
29Disease-Specific Quality of Life Rating Form
for IBD Patient Concerns
30Top IBD Patient Concerns
31Overall Concern Levels Vary by Country
32International IBD Patient Concerns
33UC Concerns Varying Much or Little Among Countries
34CD Concerns Varying Much or Little Among Countries
35Coping Styles Associated with Poor Quality of Life
36Positive Impact of the Belief that Stress Affects
IBD
37Negative Impact of the Belief that Stress Affects
IBD
38Adaptive Triad in IBD Psychotherapy
39Credit Slide