Purin nukleotidok bioszintzise

1
Purin nukleotidok bioszintézise
Phosphoribosylglycinamideformyltransferase
ATP
ATP
Phosphoribosylglycinamidesynthetase
PRPPSynthetase
Amidophosphoribosyltransferase
Phosphoribosylamine
Glycinamideribonucleotide
P-Ribose
PRPP
N10-FormylTHF
THF
ATP
Phosphoribosylformylglycinamidinesynthetase
Phosphoribosylaminoimidazolesynthetase
Phosphoribosylaminoimidazolecarboxylase
5-aminoimidazoleribonucleotide
Formylglycinamideribonucleotide
Formylglycinamidineribonucleotide
5-aminoimidazole4-carboxylateribonucleotide
Phosphoribosylaminoimidazolesuccinocarboxamides
ynthetase
ATP
N10-FormylTHF
THF
IMPcyclohydrolase
Phosphoribosylaminoimidazolecarboxamideformyltr
ansferase
Adenylosuccinate lyase
5-aminoimidazole4-Nsuccinocarboxamideribonucleot
ide
5-Formamidoimidazole4-carboxamideribonucleotide
5-aminoimidazole4-carboxamideribonucleotide
IMP
2
Formation of ATP and GTP from IMP
Purine de novo synthesis
GDP
Adenylatekinase
Adenylosuccinatelyase
Adenylatekinase
GTP
Adenylosuccinate
AMP
ADP
ATP
Adenylosuccinatesynthase
AMP PP
IMP
NAD
ATP
ADP
ADP
NADH
ATP
ATP
IMPdehydrogenase
GMPsynthase
Nucleosidemonophosphatekinase
Nucleosidediphosphatekinase
XMP
GMP
GDP
GTP
Synthesis of purine nucleoside di- and
triphosphate
3
De novo pyrimidine synthesis
Carbamoyl phosphateSynthetase II
Dihydroorotase
Aspartatetranscarbamoylase
2 ATP
Carbamoylphosphate
Dihydroorotate
Dihydroorotate
Carbamoylaspartate
Orotate
PRPPSynthetase
Mitochondrion
ATP
Phosphoribose
PRPP
Orotate
Orotidine5-monophosphate
UMP