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Tissuebanking System Review
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Functionality that should be recommended for workspace projects ... Li Zeng (MSKCC) Brian Cundiff (NU) Adekunle Raji (NU) Bill Grizzle (UAB) Kathy Sexton (UAB) ... – PowerPoint PPT presentation
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Title: Tissuebanking System Review
1
Tissuebanking System Review
- Andrew Q. Winter
- Northwestern University
- 10/27/2005
2
The goal
- To review 6 existing tissue banking systems to
identify - Vocabularies that can be leveraged
- Functionality that should be recommended for
workspace projects - Produce a checklist/scorecard for a Consumer
Reports-type synopsis of a cross-section of
systems
3
Systems identified for review
- Solicited suggestions for systems to review from
the Workspace - Narrowed the list down to 6
- Dataworks Development, Inc Freezerworks
- Duke University MAW3
- Memorial Sloan Kettering Cancer Center CRDB
- University of Alabama, Birmingham CHTN
- two others
4
Systems identified for review
- Two systems ultimately had to be removed from the
review due to various issues including - Changes in personnel
- Applying for caBIG funding
- General timing issues
5
Creation of the Checklist
- Worked with Kim Johnson (Duke/CALGB) to create a
scorecard for both this SOW and her evaluation of
cooperative group banking systems. - Contains 127 items broken into 11 sections
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Checklist sections
- Introduction
- Architecture
- Security
- Auditing
- Software Interface
- Reporting
- Patient Management
- Sample/Specimen Management
- Biospecimen storage
- Data Sharing
- Pathology Diagnosis
7
Commonalities across all systems
- Track biospecimens by patient
- Track specimen/sample relationships
- Store biospecimen annotations
- Request sample withdrawal from a bank
- Reflect the shipment of a sample
- Reflect the depletion of a specimen
8
Commonalities (continued)
- Display the location of samples
- Auditing of changes
- All employ a native security system
- All use role-based security (more or less)
9
Summary Freezerworks
- Advantages
- Professional product with support
- Runs on Windows, Mac, web client in testing
- Excellent auditing
- Sophisticated (though complicated and slow)
querying
- Limitations
- Not especially customizable for workflow
- Managing users is cumbersome
- Runs on obscure database (4D)
- No published API or official access to the tables
10
Summary MAW3 (Duke)
- Advantages
- Impressive de-identification mechanism
- Querying/searching paradigm throughout interface
- Uses common ontology (SNOMED)
- Stores and parses pathology reports, similar to
caTIES
- Limitations
- Presently only used for two banking studies
- Windows/IE only interface
- Designed to specifically meet Dukes needs
11
Summary CHTN (UAB)
- Advantages
- Interesting approach to managing investigators
and projects - Networked to all CHTN sites
- Searches samples across multiple banks, locations
- Limitations
- Very busy interface to meet CHTN needs
- Large grain role-based security (admin/user)
- No anonymization/de-identification
- Barcoding not in scope for CHTN system
12
Summary CRDB (MSKCC)
- Advantages
- Integrated with CTMS system, providing patient
outcomes information - Uses CPT codes for surgical procedures
- Incorporates business rules such as automatic
verification of consent status
- Limitations
- Relies heavily on Oracle technologies
- Built specifically to address MSKCCs workflow
13
Thanks
- Raj Dash (Duke)
- Chris Hubbard (Duke)
- Kim Johnson (Duke)
- John Speakman (MSKCC)
- Li Zeng (MSKCC)
- Brian Cundiff (NU)
- Adekunle Raji (NU)
- Bill Grizzle (UAB)
- Kathy Sexton (UAB)
