141 Glycosylase PPTs View free & download

MutY ADENINE DNA GLYCOSYLASE PowerPoint PPT Presentation

MutY ADENINE DNA GLYCOSYLASE - FORMATION OF THE ABASIC SITE. General Mechanism of action of DNA glycosylase ... Abasic site/AP site. Normal DNA. 8-oxo guanine. c complex. Major goals ...

FORMATION OF THE ABASIC SITE. General Mechanism of action of DNA glycosylase ... Abasic site/AP site. Normal DNA. 8-oxo guanine. c complex. Major goals ...

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DNA REPAIR - In Vitro Mutagenesis dut ung ... or phage grown in a dut ung mutant of E. coli. ... The ung gene encodes uracil N-glycosylase which normally removes U from DNA. ...

In Vitro Mutagenesis dut ung ... or phage grown in a dut ung mutant of E. coli. ... The ung gene encodes uracil N-glycosylase which normally removes U from DNA. ...

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Base Excision and DNA Binding Activities PowerPoint PPT Presentation

Base Excision and DNA Binding Activities - Are Sensitive to the Base Paired with a Lesion ... Damage Tolerance (Coping with damage for life continuance) DNA Removal Types ...

Are Sensitive to the Base Paired with a Lesion ... Damage Tolerance (Coping with damage for life continuance) DNA Removal Types ...

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The Mutability and Repair of DNA PowerPoint PPT Presentation

The Mutability and Repair of DNA - The Mutability and Repair of DNA Gamma radiation and X-rays Cause double-strand breaks in the DNA, which are difficult to repair. Ionizing radiation and agents like ...

The Mutability and Repair of DNA Gamma radiation and X-rays Cause double-strand breaks in the DNA, which are difficult to repair. Ionizing radiation and agents like ...

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http://goo.gl/9acqtM PowerPoint PPT Presentation

http://goo.gl/9acqtM - parp1 , 3. * .

parp1 , 3. * .

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HerbertMistry 1 PowerPoint PPT Presentation

HerbertMistry 1 - Virtual Free Radical School. SFRBM Education Program. Herbert/Mistry 2. DNA Oxidation: Repair ... deoxynucleotides opposite a template strand during DNA ...

Virtual Free Radical School. SFRBM Education Program. Herbert/Mistry 2. DNA Oxidation: Repair ... deoxynucleotides opposite a template strand during DNA ...

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Instability: Mutation and DNA repair PowerPoint PPT Presentation

Instability: Mutation and DNA repair - Instability: Mutation and DNA repair. Different mutation rates in primates and rodents ... Instability: Mutation and DNA repair. Mobile elements and mutations ...

Instability: Mutation and DNA repair. Different mutation rates in primates and rodents ... Instability: Mutation and DNA repair. Mobile elements and mutations ...

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DNA damage and repair summary PowerPoint PPT Presentation

DNA damage and repair summary - HNPCC results from mutations in genes involved in DNA mismatch repair, ... The other strand of the duplex is displaced. Double-strand break repair ...

HNPCC results from mutations in genes involved in DNA mismatch repair, ... The other strand of the duplex is displaced. Double-strand break repair ...

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Oxidative Damage of DNA PowerPoint PPT Presentation

Oxidative Damage of DNA - Title: Slide 1 Author: Frank Horodyski Last modified by: Allan M. Showalter Created Date: 2/26/2004 11:06:38 PM Document presentation format: On-screen Show (4:3)

Title: Slide 1 Author: Frank Horodyski Last modified by: Allan M. Showalter Created Date: 2/26/2004 11:06:38 PM Document presentation format: On-screen Show (4:3)

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DNA Repair - DNA Repair & Recombination All 3 genomes in plants constantly being damaged by UV and other forms of radiation, chemicals, and other stresses (e.g., oxidative, heat).

DNA Repair & Recombination All 3 genomes in plants constantly being damaged by UV and other forms of radiation, chemicals, and other stresses (e.g., oxidative, heat).

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Mutations and mutagens PowerPoint PPT Presentation

Mutations and mutagens - Mutations and mutagens Transitions and transversions Causes of transitions Causes of transversions Errors in Replication Origin: spontaneous (naturally occurring) or ...

Mutations and mutagens Transitions and transversions Causes of transitions Causes of transversions Errors in Replication Origin: spontaneous (naturally occurring) or ...

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Instability: Mutation and DNA repair - Instability: Mutation and DNA repair Mutations DNA repair What are SINEs? 1. Interspersed Elements 2. 70 - 300 Bases in Length 3. Very High Copy Numbers (100,000 ...

Instability: Mutation and DNA repair Mutations DNA repair What are SINEs? 1. Interspersed Elements 2. 70 - 300 Bases in Length 3. Very High Copy Numbers (100,000 ...

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Genetics News PowerPoint PPT Presentation

Genetics News - Genetics News. Mutation - Overview. Mechanism of mutation. Spontaneous. Induced ... 2. AP endonuclease. Combine both into one strain. Phenotype? ...

Genetics News. Mutation - Overview. Mechanism of mutation. Spontaneous. Induced ... 2. AP endonuclease. Combine both into one strain. Phenotype? ...

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Objectives of DNA recombination PowerPoint PPT Presentation

Objectives of DNA recombination - Homologous recombination of E. coli Identification of genes involved in ... isolation of mutants affecting recombination in recB recC sbcB or recB ...

Homologous recombination of E. coli Identification of genes involved in ... isolation of mutants affecting recombination in recB recC sbcB or recB ...

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DNA repair Chapter 5 4th edition MBoC PowerPoint PPT Presentation

DNA repair Chapter 5 4th edition MBoC - Xeroderma pigmentosum XP A-G...skin cancer, neurological abnormalities. NER. Ataxia telangiectasia AT. Leukemia, lymphoma cellular X&g ray sensitivity genome ...

Xeroderma pigmentosum XP A-G...skin cancer, neurological abnormalities. NER. Ataxia telangiectasia AT. Leukemia, lymphoma cellular X&g ray sensitivity genome ...

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Mutations - ... Reliance on pedigrees Possible to determine sex linkage, ... Mutation rate depends on species and on gene Generally, mutations are random Hot spot: ...

... Reliance on pedigrees Possible to determine sex linkage, ... Mutation rate depends on species and on gene Generally, mutations are random Hot spot: ...

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Mutations, Mutagenesis, and Repair PowerPoint PPT Presentation

Mutations, Mutagenesis, and Repair - Nonsense mutation---base pair substitution results in a stop codon (and shorter polypeptide) Frameshift mutations additions or deletions.

Nonsense mutation---base pair substitution results in a stop codon (and shorter polypeptide) Frameshift mutations additions or deletions.

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Molecular Techniques II PowerPoint PPT Presentation

Molecular Techniques II - ... ELIZA only using Oligonucleotides rather than Antibodies Molecular Typing Techniques RFLP/AFLP AP/RAPD PCR TRFLP RFLP AFLP RAPD-PCR TRFLP Proteomic ...

... ELIZA only using Oligonucleotides rather than Antibodies Molecular Typing Techniques RFLP/AFLP AP/RAPD PCR TRFLP RFLP AFLP RAPD-PCR TRFLP Proteomic ...

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Methyldirected mismatch repair in E. coli: PowerPoint PPT Presentation

Methyldirected mismatch repair in E. coli: - MutL helps to recruit MutH, which recognizes and cleaves one DNA strand (the ... example: Benzo-[a]-pyrene (one of the primary carcinogens in tar) is metabolized ...

MutL helps to recruit MutH, which recognizes and cleaves one DNA strand (the ... example: Benzo-[a]-pyrene (one of the primary carcinogens in tar) is metabolized ...

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DNA Replication and Repair PowerPoint PPT Presentation

DNA Replication and Repair - DNA Replication and Repair Replication is bidirectional E. coli genome size = 4.6 X 106 bp Bacteria have circular chromosome with single origin of replication.

DNA Replication and Repair Replication is bidirectional E. coli genome size = 4.6 X 106 bp Bacteria have circular chromosome with single origin of replication.

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DNA Ligase - ... cell death Maintenance signals cell immortality Most normal cells have no telomerase Cancer cells have telomerase Progeria, premature aging, ...

... cell death Maintenance signals cell immortality Most normal cells have no telomerase Cancer cells have telomerase Progeria, premature aging, ...

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Definitions: PowerPoint PPT Presentation

Definitions: - How does the mismatch repair system accurately detect, remove and repair the ... which spares the cell the worse fate of an incompletely replicated chromosome ...

How does the mismatch repair system accurately detect, remove and repair the ... which spares the cell the worse fate of an incompletely replicated chromosome ...

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Mutations - Mutations Mutations are inheritable changes in the DNA Failure to faithfully store genetic information Changes can be to chromosomes or genes

Mutations Mutations are inheritable changes in the DNA Failure to faithfully store genetic information Changes can be to chromosomes or genes

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Chapt 20 DNA Replication I: Basic Mechanism and Enyzmology PowerPoint PPT Presentation

Chapt 20 DNA Replication I: Basic Mechanism and Enyzmology - Chapt 20 DNA Replication I: Basic Mechanism and Enyzmology Student learning outcomes: Describe general features of semi-conservative DNA replication: leading, lagging ...

Chapt 20 DNA Replication I: Basic Mechanism and Enyzmology Student learning outcomes: Describe general features of semi-conservative DNA replication: leading, lagging ...

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DNA - ... reversal mechanism ????. Directly undoing DNA damage. 2. Excision ... ????????????????????????? ????Directly undoing DNA damage. 1.1 Light-dependent repair ...

... reversal mechanism ????. Directly undoing DNA damage. 2. Excision ... ????????????????????????? ????Directly undoing DNA damage. 1.1 Light-dependent repair ...

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RADIATION DAMAGE TO DNA : FROM NUCLEOSIDES TO THE CELL PowerPoint PPT Presentation

RADIATION DAMAGE TO DNA : FROM NUCLEOSIDES TO THE CELL - Gamma ray-mediated formation of DNA damage in isolated calf thymus DNA in ... Yields of formation of 11 base modifications in the DNA of monocytes upon ...

Gamma ray-mediated formation of DNA damage in isolated calf thymus DNA in ... Yields of formation of 11 base modifications in the DNA of monocytes upon ...

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Bioinformaticians Experimentalists = Successful Protein Analysis PowerPoint PPT Presentation

Bioinformaticians Experimentalists = Successful Protein Analysis - Bioinformaticians + Experimentalists = Successful Protein Analysis Katarzyna Poleszak International Institute of Molecular and Cell Biology Laboratory of ...

Bioinformaticians + Experimentalists = Successful Protein Analysis Katarzyna Poleszak International Institute of Molecular and Cell Biology Laboratory of ...

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Genetic Toxicology PowerPoint PPT Presentation

Genetic Toxicology - Genetic Toxicology Genetic toxicology Subspeciality of toxicology Involves the identification and analysis of agents with toxicity ...

Genetic Toxicology Genetic toxicology Subspeciality of toxicology Involves the identification and analysis of agents with toxicity ...

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DNA Replication and Repair - DNA polymerase has 3' to 5' exonuclease function (epsilon-subunit) that ... Terminator utilization substance (Tus) binds to ter region. ...

DNA polymerase has 3' to 5' exonuclease function (epsilon-subunit) that ... Terminator utilization substance (Tus) binds to ter region. ...

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Lectures 78: PowerPoint PPT Presentation

Lectures 78: - Benzo(a)pyrene. Base damage through bulky adducts. T A. G C. How ... Metabolic conversion of benzo(a)pyrene into a mutagen. Diol epoxide. Ames test. Paper disc ...

Benzo(a)pyrene. Base damage through bulky adducts. T A. G C. How ... Metabolic conversion of benzo(a)pyrene into a mutagen. Diol epoxide. Ames test. Paper disc ...

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Welcome to My Molecular Biology Class PowerPoint PPT Presentation

Welcome to My Molecular Biology Class - Welcome to My Molecular Biology Class. Molecular Biology of the Gene, 5/E ... a low mutation rate can drive the evolvement of a new species if the cell ...

Welcome to My Molecular Biology Class. Molecular Biology of the Gene, 5/E ... a low mutation rate can drive the evolvement of a new species if the cell ...

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NUTRITION, METABOLISM PowerPoint PPT Presentation

NUTRITION, METABOLISM - at increasingly rapid rates. Enzymatic reactions occurring. at maximal ... Psychrophile. Mesophile. Example: Escherichia. coli. 39 4 60 Example: Geobacillus ...

at increasingly rapid rates. Enzymatic reactions occurring. at maximal ... Psychrophile. Mesophile. Example: Escherichia. coli. 39 4 60 Example: Geobacillus ...

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Epigenetic regulation during early embryogenesis PowerPoint PPT Presentation

Epigenetic regulation during early embryogenesis - Epigenetic regulation during early embryogenesis reprogramming and remodelling Helena Fulkova Istitute of Animal Science, www.vuzv.cz helena.fulkova@vuzv.cz

Epigenetic regulation during early embryogenesis reprogramming and remodelling Helena Fulkova Istitute of Animal Science, www.vuzv.cz helena.fulkova@vuzv.cz

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DNA Replication and Repair - DNA Polymerase Binds Template and Free dNTP. Processive Replication ... Trombone Model of DNA Replication in E. coli V. Helicase Binds to DNA Polymerase III ...

DNA Polymerase Binds Template and Free dNTP. Processive Replication ... Trombone Model of DNA Replication in E. coli V. Helicase Binds to DNA Polymerase III ...

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Rapid Methods for Foodborne PowerPoint PPT Presentation

Rapid Methods for Foodborne - [Microbiology International] Large Lab-based Systems. Conductance-based ... 144.3 million microbiology tests. 5,979 processing plants. Avg. 464 tests/week 24,000/y ...

[Microbiology International] Large Lab-based Systems. Conductance-based ... 144.3 million microbiology tests. 5,979 processing plants. Avg. 464 tests/week 24,000/y ...

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Nucleotides and Nucleic Acids PowerPoint PPT Presentation

Nucleotides and Nucleic Acids - Mainly original content ... Presented by Dr. Brett Helms, Molecular Foundry Lawrence Berkeley National Laboratories Berkeley, California

Mainly original content ... Presented by Dr. Brett Helms, Molecular Foundry Lawrence Berkeley National Laboratories Berkeley, California

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Chapter 9 The Mutability and Repair of DNA PowerPoint PPT Presentation

Chapter 9 The Mutability and Repair of DNA - Repair of DNA damage. Life and Biodiversity Depend on a Happy Balance between Mutation and Its Repair ... Mend the lesions ...

Repair of DNA damage. Life and Biodiversity Depend on a Happy Balance between Mutation and Its Repair ... Mend the lesions ...

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DNAReplication and Repair - Ligation. DNA-Ligase. E. coli. Viren/ Menschen. Initiation site of replication ... 54kDa, Chromophores: FADH2, 5, 10-Methenyltetrahydrofolylglutamat. Direct. Repair ...

Ligation. DNA-Ligase. E. coli. Viren/ Menschen. Initiation site of replication ... 54kDa, Chromophores: FADH2, 5, 10-Methenyltetrahydrofolylglutamat. Direct. Repair ...

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Reactive Oxygen Species and DNA Damage PowerPoint PPT Presentation

Reactive Oxygen Species and DNA Damage - DNA base products of interaction with ROS. Repair of Pyrimidine and Purine ... Disease by age 50, probably because chromosome 21 carries the amyloid gene. ...

DNA base products of interaction with ROS. Repair of Pyrimidine and Purine ... Disease by age 50, probably because chromosome 21 carries the amyloid gene. ...

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DNA Repair - Biochemistry

Biochemistry

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Chapter 9 The Mutability and Repair of DNA - Low rates of mutation can drive evolution. High rates of mutation can be catastrophic ... Mend the lesions and restore the original DNA. The Nature of Mutations ...

Low rates of mutation can drive evolution. High rates of mutation can be catastrophic ... Mend the lesions and restore the original DNA. The Nature of Mutations ...

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Chapter 9 The Mutability and Repair of DNA - Transitions:a kind of the simplest mutations which are pyrimidine-to-pyrimidine ... by transposon or by aberrant action of cellular recombination processes. ...

Transitions:a kind of the simplest mutations which are pyrimidine-to-pyrimidine ... by transposon or by aberrant action of cellular recombination processes. ...

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from Marnett and Plastaras, Trends Genet' 17, 214 2001 PowerPoint PPT Presentation

from Marnett and Plastaras, Trends Genet' 17, 214 2001 - Biological Molecules are Labile. RNA is susceptible to hydrolysis ... N-glycosyl bond of DNA is more labile. DNA damage occurs from normal cellular operations ...

Biological Molecules are Labile. RNA is susceptible to hydrolysis ... N-glycosyl bond of DNA is more labile. DNA damage occurs from normal cellular operations ...

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DNA1: (Last week) PowerPoint PPT Presentation

DNA1: (Last week) - DNA1: (Last week) Types of mutants Mutation, drift, selection Binomial for each Association studies c2 statistic Linked & causative alleles Alleles, Haplotypes, genotypes

DNA1: (Last week) Types of mutants Mutation, drift, selection Binomial for each Association studies c2 statistic Linked & causative alleles Alleles, Haplotypes, genotypes

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Secondhand Smoke and Nevada Casino Workers: Exposure and Health Risks PowerPoint PPT Presentation

Secondhand Smoke and Nevada Casino Workers: Exposure and Health Risks - Secondhand Smoke and Nevada Casino Workers: Exposure and Health Risks Dr. Chris A. Pritsos University of Nevada Reno, Nevada Estimated Health Impact from ETS Exposure ...

Secondhand Smoke and Nevada Casino Workers: Exposure and Health Risks Dr. Chris A. Pritsos University of Nevada Reno, Nevada Estimated Health Impact from ETS Exposure ...

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DNA repair - a large multienzyme compound scans the DNA strand for anomalities ... the gap is repaired by DNA polymerase and DNA ligase enzymes. Double strand repair 1/2 ...

a large multienzyme compound scans the DNA strand for anomalities ... the gap is repaired by DNA polymerase and DNA ligase enzymes. Double strand repair 1/2 ...

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The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA PowerPoint PPT Presentation

The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA - The cytidine deaminase CEM15 induces hypermutation in newly ... Sequence resulting nucleic acids. Result: No discernible mutations were found upon sequencing ...

The cytidine deaminase CEM15 induces hypermutation in newly ... Sequence resulting nucleic acids. Result: No discernible mutations were found upon sequencing ...

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Evolutionary Response to Chemicals in the Environment PowerPoint PPT Presentation

Evolutionary Response to Chemicals in the Environment - Evolutionary Response to Chemicals in the Environment Introduction to Detoxification enzymes (focusing on cytochrome P450s) Evolutionary response to toxins (pesticides)

Evolutionary Response to Chemicals in the Environment Introduction to Detoxification enzymes (focusing on cytochrome P450s) Evolutionary response to toxins (pesticides)

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Applications of Dynamic Programming PowerPoint PPT Presentation

Applications of Dynamic Programming - 1. Applications of Dynamic Programming. To sequence analysis. Shotgun sequence ... Global (e.g. haplotype) ACCACACA ::xx::x: ACACCATA. Score= 5( 1) 3(-1) = 2 ...

1. Applications of Dynamic Programming. To sequence analysis. Shotgun sequence ... Global (e.g. haplotype) ACCACACA ::xx::x: ACACCATA. Score= 5( 1) 3(-1) = 2 ...

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Nucleic Acid Amplification - Nucleic Acid Amplification

Nucleic Acid Amplification

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Welcome Each of You to My Molecular Biology Class PowerPoint PPT Presentation

Welcome Each of You to My Molecular Biology Class - Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part ... Part II: Maintenance of the Genome. Dedicated to the structure of DNA and the processes ...

Molecular Biology of the Gene, 5/E --- Watson et al. (2004) Part ... Part II: Maintenance of the Genome. Dedicated to the structure of DNA and the processes ...

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Human Molecular Genetics PowerPoint PPT Presentation

Human Molecular Genetics - Human Molecular Genetics Dr. Yu-Wai Peter Lin Barry University School of Natural and Health Sciences DNA Structure and Function DNA, RNA and polypeptides are large ...

Human Molecular Genetics Dr. Yu-Wai Peter Lin Barry University School of Natural and Health Sciences DNA Structure and Function DNA, RNA and polypeptides are large ...

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Objectives of DNA recombination - Contain nuclease (exonuclease and Chi-specific ... recR, recQ, recJ ... RecA forms filaments with single-stranded DNA and catalyzes the assimilation of ...

Contain nuclease (exonuclease and Chi-specific ... recR, recQ, recJ ... RecA forms filaments with single-stranded DNA and catalyzes the assimilation of ...

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35 Proofreading Repair by Klenow Fragment of DNA pol I PowerPoint PPT Presentation

35 Proofreading Repair by Klenow Fragment of DNA pol I - However, pol III in a multi-protein aggregate termed the ... on lagging strand must bind and dissociate constantly, yet keep at same pace as leading strand ...

However, pol III in a multi-protein aggregate termed the ... on lagging strand must bind and dissociate constantly, yet keep at same pace as leading strand ...

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Damage to the Host PowerPoint PPT Presentation

Damage to the Host - ... contribution of toxin to pathogenesis fitness is not clear (e.g. staphylococcal ... Increased cAMP, secretion. Direct cell damage/lysis. Biological effect. DNA ...

... contribution of toxin to pathogenesis fitness is not clear (e.g. staphylococcal ... Increased cAMP, secretion. Direct cell damage/lysis. Biological effect. DNA ...

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Primary IDS: Single gene Defects Xlinked PowerPoint PPT Presentation

Primary IDS: Single gene Defects Xlinked - Wiskott-Aldrich/XLT WASP. X-SCID Common y-chain XLP SAP/SH2D1A. X-CGD gp91-phox. IPEX FOXP3 ... WASP Mutation scores. Score '0' no WAS/XLT findings, e.g. XLN ...

Wiskott-Aldrich/XLT WASP. X-SCID Common y-chain XLP SAP/SH2D1A. X-CGD gp91-phox. IPEX FOXP3 ... WASP Mutation scores. Score '0' no WAS/XLT findings, e.g. XLN ...

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Glycosylase PowerPoint PPT Presentations