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Title: PowerPoint Author: Zhang Ying Jian Last modified by: Created Date: 9/29/2001 2:13:45 AM Document presentation format
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The same number of cells must be removed to maintain homeostasis. This occurs by Apoptosis and/or Autophagy. Life. Death. Too Much vs. Too Little Cell Death ...
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Recognize tetrapeptide sequence on substrates (P4-P3-P2-P1). P4 P3 P2 P1 P1' P2' ... SABLE1. Propensity for. secondary structures. Propensity for. solvent exposure ...
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The Caspases, and Their Role in Apoptosis. Some caspases have long ... http://homepage.ntlworld.com/markhewitson/ntlup.swf. Caspases are:- Cysteine proteases ...
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A Role for Caspases During Viral Infection of the Coccolithophorid, ... There is a misconception that phytoplankton are immortal unless eaten by grazers. ...
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Is there a relationship between moon phase and birthrate? Finkenthal, N., and Woo, S. Desert View High School, Tucson, Arizona INTRODUCTION: The moon has been linked ...
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Phosphodiesterase PDE5 Phosphodiesterase PDE6 Peptidase: Caspase 1 Peptidase: Caspase 3 Peptidase: Caspase 6 Peptidase: Caspase 7 Peptidase: Caspase 8
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p-FOXO. BrDU. Caspase-3. p-Akt. total Akt. pAkt. acid+leptin. time. total Bad. pBad. total FOXO. pFOXO.
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... PLCg STAT NIK IKK Smad STAT STAT STAT Smad Smad Smad PLCb Caspases Phosphorylation is key A. Receptor tyrosine kinase (RTK) ... (Ligand) Notch (receptor) ...
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Signal Transduction and Apoptosis The wider Bcl-2 family Functional role of CED-9/CED-4/CED-3 complexes Model of receptor-mediated caspase activation Intrinsic cell ...
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Programmed Cell Death. Mitochondria in Apoptosis. Caspase Cascade. Granzyme B ... ATM/p53 Signaling Pathway. Integrin Signaling in Cell Survival and Death ...
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Activating mutations in AKT or inactivating mutations in PTEN ... p53 - Activated by DNA damage. ... Active caspase-8 activates 'downstream' caspases, which ...
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Full enzymology support through Lead Optimization. Other. CK1a ... All enzymology for Hit-to-Lead in place. Protease Panel. ADAM 10. Furin. ACE 2. Caspase 8 ...
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Animal Genetics and Breeding Division, #Animal Biochemistry ... 'Extrinsic Pathway' 'Intrinsic Pathway' MAJOR PLAYERS IN APOPTOSIS. Caspases. Adaptor proteins ...
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Neural tube (3 wk) / nervous system) Three subdivisions (future forebrain, midbrain, hindbrain) ... Diablo gene released. Block IAPs. Caspases no longer ...
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Apoptosis Market research report gives an insight into Apoptosis Mechanism, by Molecular Pathways, Caspase Activators and Inhibitors, Protease/Proteasome Inhibitors, Bcl-2 Modulators, p53 Modulators and Other. See Full Report @ http://bit.ly/1KdUj5P
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Blast sequence against database for known proteins or construct a possible ... A cloning method for caspase substrates that uses the yeast two-hybrid system: ...
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Bcl-2 and Bcl-xL bind and inhibit Apaf-1 and prevent caspase activation. ... Bryostatin-1 also decreases expression of cyclin B, preventing Cdc2 activation. ...
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Regulates Akt activation and subsequent phosphorylation of Bad. ... Necessary for activation of caspase-9 following cytochrome c release. ...
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caspases in the cell: these leads to a 'caspase cascade', resulting in cleavage. of nuclear lamina, DNA and other cellular proteins. p53. Guardian of the Genome ...
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Ligation of Fas also leads to a disruption in cyto c function in electron transport. ... (primarily caspase-8) recruited to the cytosolic domain of ligated Fas (21) ...
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Biological Basis of Downs Syndrome and Alzheimer's Disease. Trevor Phinney. Alex Hansler ... other downstream caspases that have direct effects on cell death ...
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... c-IAP-1, and cIAP-2 have been shown to inhibit caspase-3, -7, and -9. Survivin ... an IAP-inhibiting protein, Smac/ DIABLO, thus releassing IAP to suppress ...
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Pr C . Preudhomme ... 1 MAP/SAP kinases PI3 kinase Akt Cytosquelette ADHESION PROLIFERATION APOPTOSE BAD Cytochrome C Caspases Prot ine kinase ADN d pendante DNA ...
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The Death Domain (DD) is an 80aa C-terminal domain shared among a large family ... mt. mt. Bcl-2. Apaf-1. Caspase9. Blk/Bax. Apoptotic Pathways are Initiated on ...
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... refer to the inactive and active forms of Cyclin E/CDK2, respecive ... where C9z = procaspase-9, C9a = active caspase-9, I9 = decoy protein that competes ...
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Title: xiap Last modified by: User Document presentation format: (4:3) Other titles: Calibri Arial Wingdings ...
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cell senescence and death ...
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TNF 00 12 17 Death Receptors: Signaling and Modulation Science 1998 281:1305 ...
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Title: PowerPoint Author: litao Last modified by: zhangql Created Date: 3/3/2005 2:10:52 PM Document presentation format:
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JC-1 fluorescence on a flow cytometer. Fl-1 and Fl-2 channels: J-aggregates (healthy cell) ... Start-up the flow cytometer. Perform standard instrument operation check ...
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Isoflurane and Alzheimer s Disease Neuropathogenesis Zhongcong Xie, M.D., Ph.D. Genetics and Aging Research Unit MassGeneral Institute for Neurodegenerative Disease
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Cell Death Jaroslava Du kov Inst. Pathol. ,1st Med. Faculty, Charles Univ. Prague http://www1.lf1.cuni.cz/~jdusk/
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Title: Pr sentation PowerPoint Author: delphine Last modified by: delphine Created Date: 11/22/2004 9:09:29 AM Document presentation format: Affichage l' cran
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Effects of smoking in human lens epithelial cells Jae-Woong Koh (MD/PhD)1, Nang-Hee Song(MD)1, Gil-Joong Yoon (MD/PhD)2 Department of Ophthalmology, Chosun University ...
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Title: Apresenta o do PowerPoint Author: George Reis Last modified by: dantasap Created Date: 8/3/2004 5:22:43 PM Document presentation format
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Biophys. Acta, 1659, 178-189 Virus peuvent 1 ... PM K7 or vIAP KSHV STS, anti-Fas M F1L Vaccinia STS, anti-Fas, PPIX PBR M M11L Myxoma Oxidants, anti ...
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Chap. 21 Stem Cells, Cell Asymmetry, and Cell Death Topics Cell Death and Its Regulation Goals Learn the basic mechanism of apoptosis and its regulation.
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Mechanisms of Apoptosis and Cytotoxicity
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Macrophage/CD4+ CCR5+ Th1 lymphocytes cross-talk during MTB/HIV ... Reinforced HIV replication and mycobacterial dissemination IL-1b/TNF-a HIV MTB TLR-2 La ...
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* * CHAPTER 11 APOPTOSIS AND AGING I. Aging of cell The sorting of human cells by their recruitment: Human natural life time is about 120 years.
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Cryptosporidium generally infects the apical layer of endothelial cells of the ... that cell lysis occurs at these parasitophorous vacuoles at the apical membrane. ...
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PUMA. Stress. Mitochondria. Adapted from Ashkenazi A. Nat Rev Cancer 2002;2:420 430. ... of pro-apoptotic members of the BCL2 family of proteins such as PUMA and BAX ...
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Protective effects of chitosan oligosaccharide on paraquat-induced nephrotoxicity in rats Byung Chul Shin, Wan Soo Lee, Dae Wong Kang, Jong Hoon Chung and Hyun Lee Kim
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Figure 17.1 Apoptosis Figure 17.2 Phagocytosis of apoptotic cells Key Experiment 17.1: Photomicrographs of a normal worm (A) and a ced-3 mutant (B) Figure 17.3 ...
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life cycle pause between EB and RB stages -stable association ... needed for embryogenesis, immune system maintenance. Necrosis non-programmed cell death. ...
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Granzyme B and perforin, proteins released by an effector cell (cytotoxic T cell) ... II (Topo II) to condense chromatin, leading to DNA fragmentation and ...
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Title: Apresenta o do PowerPoint Author: Paulo Cabeda Last modified by: Jcabeda Created Date: 9/29/2001 2:36:41 PM Document presentation format
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MORT CELLULAIRE CONCEPTS ET VOIES DE MORT NECROSE APOPTOSE AUTOPHAGY NECROSE La n crose est une mort anormale de la cellule (cf. apoptose) Causes possibles : Perte ...
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Cancer Biology: Apoptosis
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Programmed Cell Death Death Signaling Pathways TNF/FASL TNF is a protein toxin which is secreted by activated macrophages and monocytes Laster et al., using time ...
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Some TNFa induced signaling pathways TNF-mediated clustering TNFa TNFa TNFR2 TNFR1 TNF-Receptor 1 TNF-Receptor 2 (p75) (p55) TRAF2 DD TRADD FADD TRAF-domain
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LEQ: Why is the eukaryotic cell cycle regulated? Key terms: cyclin, growth factor, kinase Reading 5.3 (cancer) Activator: Briefly explain why the daughter cells ...
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Protein Lysate Microarrays Clay Scott Ryan McConnell Shannon Neeley
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Apoptosis: Programmed Cell Death A story about 7th October 2002 3 King
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