724 Brca1 PPTs View free & download

What We've Learned from Studying Hereditary Cancer Families BRCA1, BRCA2, and NonBRCA: A Tale of Thr PowerPoint PPT Presentation

What We've Learned from Studying Hereditary Cancer Families BRCA1, BRCA2, and NonBRCA: A Tale of Thr - Yale University Elizabeth Claus, Ellen Matloff. PROSE/MAGIC Team at Penn ... Shannon Chuai. Nandita Mitra. Fei Wan. Co-Investigators Susan Domchek. Kate Nathanson ...

Yale University Elizabeth Claus, Ellen Matloff. PROSE/MAGIC Team at Penn ... Shannon Chuai. Nandita Mitra. Fei Wan. Co-Investigators Susan Domchek. Kate Nathanson ...

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Mutation Spectrum of the Two Breast Cancer Susceptibility Genes, BRCA1 and BRCA2 in the Population PowerPoint PPT Presentation

Mutation Spectrum of the Two Breast Cancer Susceptibility Genes, BRCA1 and BRCA2 in the Population - ... Microarray Facility. Harriet Feilotter, Natasha Gallo, Jen Kreiger, Kristine Roland, Andrew Martin, ... A collaborative project aimed at developing a multi ...

... Microarray Facility. Harriet Feilotter, Natasha Gallo, Jen Kreiger, Kristine Roland, Andrew Martin, ... A collaborative project aimed at developing a multi ...

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Hereditary predisposition mutations in BRCA1 and BRCA2 genes contribute to familial breast cancers' PowerPoint PPT Presentation

Hereditary predisposition mutations in BRCA1 and BRCA2 genes contribute to familial breast cancers' - Identification of the molecular signatures would help target at-risk populations ... Gain is a concept coming from the information and decision tree theory. ...

Identification of the molecular signatures would help target at-risk populations ... Gain is a concept coming from the information and decision tree theory. ...

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Breast Cancer, BRCA2 Gene PowerPoint PPT Presentation

Breast Cancer, BRCA2 Gene - Examples from the American Cancer Society below: 100% of women survive breast cancer if it is detected before it starts to spread ...

Examples from the American Cancer Society below: 100% of women survive breast cancer if it is detected before it starts to spread ...

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BRCA1 Mutation Test Results and Heterogeneity in PsychoSocial Outcomes PowerPoint PPT Presentation

BRCA1 Mutation Test Results and Heterogeneity in PsychoSocial Outcomes - and cancer registry, family expansion. N=108 women (39 carriers) N=73 men (27 carriers) ... that has a higher than normal risk for breast and ovarian cancer? ...

and cancer registry, family expansion. N=108 women (39 carriers) N=73 men (27 carriers) ... that has a higher than normal risk for breast and ovarian cancer? ...

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BRCA1 Maintains Genomic Integrity by Regulating DNA Repair via Double Strand Break Repair Methods in PowerPoint PPT Presentation

BRCA1 Maintains Genomic Integrity by Regulating DNA Repair via Double Strand Break Repair Methods in - BRCA1 Maintains Genomic Integrity by Regulating DNA Repair via Double Strand ... ATM (ataxia telangiectasia mutated) is a protein is involved in detecting DNA ...

BRCA1 Maintains Genomic Integrity by Regulating DNA Repair via Double Strand ... ATM (ataxia telangiectasia mutated) is a protein is involved in detecting DNA ...

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Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers: Study Design and Analysis Issues PowerPoint PPT Presentation

Modifiers of Cancer Risk in BRCA1/2 Mutation Carriers: Study Design and Analysis Issues - in BRCA1/2 Mutation Carriers: Study Design and Analysis Issues Timothy R. Rebbeck University of Pennsylvania And Even More Problems Correlated Data Information ...

in BRCA1/2 Mutation Carriers: Study Design and Analysis Issues Timothy R. Rebbeck University of Pennsylvania And Even More Problems Correlated Data Information ...

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Zhang, J., H. Willers, Z. Feng, J.C. Ghosh, S. Kim, D.T. Weaver, J.H. Chung, S.N. Powell, and F. Xia. 2004. Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair. Molecular and cell biology 24: 708-718. - ... detects DNA damage ... interrupts with p53 the cell cycle when there is damage Chk2 is a kinase BRCA1 A gene located on chromosome 17 It is necessary ...

... detects DNA damage ... interrupts with p53 the cell cycle when there is damage Chk2 is a kinase BRCA1 A gene located on chromosome 17 It is necessary ...

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Phase 1b Study of Iniparib (BSI-201) Combined with Irinotecan for Treatment of Metastatic Breast Cancer1 Cell Cycle Effects of Iniparib plus Gemcitabine and Carboplatin in a Triple Negative Breast Cancer Cell Line2 Promoter CpG Methylation of BRCA1 - Sensitivity to PARP inhibitors was assessed by: Cell proliferation assays (XTT ... BRCA1 promoter methylation may be assessed as a biomarker of response in current ...

Sensitivity to PARP inhibitors was assessed by: Cell proliferation assays (XTT ... BRCA1 promoter methylation may be assessed as a biomarker of response in current ...

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Cancer Genetics PowerPoint PPT Presentation

Cancer Genetics - Breast, skin, colon. Sarcoma-connective tissue cancer. Ie. Muscle, bone ... Colon cancer 'runs in families' BRCA1, BRCA2 genes in breast cancer ...

Breast, skin, colon. Sarcoma-connective tissue cancer. Ie. Muscle, bone ... Colon cancer 'runs in families' BRCA1, BRCA2 genes in breast cancer ...

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Diapositive 1 PowerPoint PPT Presentation

Diapositive 1 - Mutations in the BRCA1 and BRCA2 breast cancer susceptibility genes Breast cancer in Europe 1 in 10 women will develop breast cancer during their life 430,000 new ...

Mutations in the BRCA1 and BRCA2 breast cancer susceptibility genes Breast cancer in Europe 1 in 10 women will develop breast cancer during their life 430,000 new ...

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Estrategias de detecci PowerPoint PPT Presentation

Estrategias de detecci - Estrategias de detecci n precoz y reducci n del riesgo en portadoras de mutaciones BRCA1 y BRCA2 Jos Ignacio Mayordomo C mara, Raquel Andr s Conejero

Estrategias de detecci n precoz y reducci n del riesgo en portadoras de mutaciones BRCA1 y BRCA2 Jos Ignacio Mayordomo C mara, Raquel Andr s Conejero

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Familial Cancer Risks PowerPoint PPT Presentation

Familial Cancer Risks - ... (standard errors) of breast cancer and ovarian cancer among relatives with BRCA1 ... Breast cancer. Ovarian cancer. BRCA1 or 2. BRCA1. BRCA2. BRCA1. BRCA2 ...

... (standard errors) of breast cancer and ovarian cancer among relatives with BRCA1 ... Breast cancer. Ovarian cancer. BRCA1 or 2. BRCA1. BRCA2. BRCA1. BRCA2 ...

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The difference between a successful person and others is not lack of strength, not lack of knowledge PowerPoint PPT Presentation

The difference between a successful person and others is not lack of strength, not lack of knowledge - 6% of all cancers in women. 5th common cancer in women. ... Gonadal Dysgenesis. Ovarian cancer genes. BRCA1 (17q12) & BRCA2(13q12) ...

6% of all cancers in women. 5th common cancer in women. ... Gonadal Dysgenesis. Ovarian cancer genes. BRCA1 (17q12) & BRCA2(13q12) ...

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DNA II - Breast Cancer gene does not make a protein needed to repair DNA ... a body of recent studies showing that BRCA2 and its related gene product BRCA1 ...

Breast Cancer gene does not make a protein needed to repair DNA ... a body of recent studies showing that BRCA2 and its related gene product BRCA1 ...

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Genetic Risk Assessment and Genetic Counseling Research PowerPoint PPT Presentation

Genetic Risk Assessment and Genetic Counseling Research - 30 January 2006. Genetic Risk Assessment and Genetic Counseling Research ... Mendelian. Claus, 1990. Twin Studies. N Engl J Med 2000;343:78-85. BRCA1 and BRCA2 ...

30 January 2006. Genetic Risk Assessment and Genetic Counseling Research ... Mendelian. Claus, 1990. Twin Studies. N Engl J Med 2000;343:78-85. BRCA1 and BRCA2 ...

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Le cancer de lovaire PowerPoint PPT Presentation

Le cancer de lovaire - Ils repr sentent moins de 10 % de tous les cancers ovariens ( BRCA1 BRCA2 ) ... Il est plus facile administrer. Equivalence Carboplatine Cisplatine( Sch ma standart ...

Ils repr sentent moins de 10 % de tous les cancers ovariens ( BRCA1 BRCA2 ) ... Il est plus facile administrer. Equivalence Carboplatine Cisplatine( Sch ma standart ...

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Genetic Susceptibility Risk Models in Clinical Decision Making PowerPoint PPT Presentation

Genetic Susceptibility Risk Models in Clinical Decision Making - Logistic regression models (Couch, Shattuck-Eidens, Frank) Bayesian formulations (BRCAPRO) ... BRCAPro: Dependent on proband 55% vs 1.6% Variability in models ...

Logistic regression models (Couch, Shattuck-Eidens, Frank) Bayesian formulations (BRCAPRO) ... BRCAPro: Dependent on proband 55% vs 1.6% Variability in models ...

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The Management of Women at High Risk of Breast Cancer PowerPoint PPT Presentation

The Management of Women at High Risk of Breast Cancer - The Management of Women at High Risk of Breast Cancer ... Hanne Meijers-Heijboer. 139. BRCA1 & BRCA2 mutation carriers. 76 63. Mean Follow up 3 years ...

The Management of Women at High Risk of Breast Cancer ... Hanne Meijers-Heijboer. 139. BRCA1 & BRCA2 mutation carriers. 76 63. Mean Follow up 3 years ...

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Diapositive 1 - Mutations in the BRCA1 and BRCA2 breast cancer susceptibility ... Presence of a deleterious mutation on the other allele of the same gene: in trans or in cis ? ...

Mutations in the BRCA1 and BRCA2 breast cancer susceptibility ... Presence of a deleterious mutation on the other allele of the same gene: in trans or in cis ? ...

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Cancer Genetics - Breast cancer, BRCA1. Retinoblastoma: Rb gene on 13q14 ... and soft tissue sarcomas, breast cancer, brain cancer, leukemia, adrenocortical ...

Breast cancer, BRCA1. Retinoblastoma: Rb gene on 13q14 ... and soft tissue sarcomas, breast cancer, brain cancer, leukemia, adrenocortical ...

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MOLECULAR BASIS OF CANCER Assoc.Prof. Isik G. Yulug Bilkent University Department of Molecular Biology and Genetics yulug@fen.bilkent.edu.tr PowerPoint PPT Presentation

MOLECULAR BASIS OF CANCER Assoc.Prof. Isik G. Yulug Bilkent University Department of Molecular Biology and Genetics yulug@fen.bilkent.edu.tr - What is the molecular basis of cancer? Cancer is a genetic disease. ... Molecular mechanisms of DNA double strand break repair. BRCA1/2. 51. IMPORTANCE OF DNA REPAIR ...

What is the molecular basis of cancer? Cancer is a genetic disease. ... Molecular mechanisms of DNA double strand break repair. BRCA1/2. 51. IMPORTANCE OF DNA REPAIR ...

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Chromosomes and Diseases PowerPoint PPT Presentation

Chromosomes and Diseases - Are humans more closely related to chimps than they are to gorillas? ... BRCA1-associate ring domain (breast cancer) Liver cancer oncogone. Muscular dystrophy ...

Are humans more closely related to chimps than they are to gorillas? ... BRCA1-associate ring domain (breast cancer) Liver cancer oncogone. Muscular dystrophy ...

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Multigeneration epidemiology using biobanks PowerPoint PPT Presentation

Multigeneration epidemiology using biobanks - familial cases (testing for known syndromes, BRCA1/2) Novel approach: registers ... Medullary thyroid cancer. SIR. High-risk cancers in FCD (genes unknown) 90 ...

familial cases (testing for known syndromes, BRCA1/2) Novel approach: registers ... Medullary thyroid cancer. SIR. High-risk cancers in FCD (genes unknown) 90 ...

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BRCA Risk factors PowerPoint PPT Presentation

BRCA Risk factors - BRCA Risk factors White Age FH (M, S, D) BRCA1&2 Endometrial Ca, fibrocystic disease, BRCA Early menarche (50) Nulliparous or late first pregnancy

BRCA Risk factors White Age FH (M, S, D) BRCA1&2 Endometrial Ca, fibrocystic disease, BRCA Early menarche (50) Nulliparous or late first pregnancy

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Laboratory experience Leeds PowerPoint PPT Presentation

Laboratory experience Leeds - Laboratory experience - Leeds. David J Cockburn. DNA ... 2003: 216 worksheets analysed so far. Diseases: Connexin 26; BRCA1&2; MEN1; MLH1; MSH2 etc...

Laboratory experience - Leeds. David J Cockburn. DNA ... 2003: 216 worksheets analysed so far. Diseases: Connexin 26; BRCA1&2; MEN1; MLH1; MSH2 etc...

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Paolo Marchetti PowerPoint PPT Presentation

Paolo Marchetti - A New Way to Treat Cancer Before It Happens ... Meijers-Heijboer et al., NEJM, 2001: in pts with BRCA1/2 mutations: surveillance alone 8 BC/63 ...

A New Way to Treat Cancer Before It Happens ... Meijers-Heijboer et al., NEJM, 2001: in pts with BRCA1/2 mutations: surveillance alone 8 BC/63 ...

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Introduction to Statistical Inference PowerPoint PPT Presentation

Introduction to Statistical Inference - Mean expression level of BRCA1 gene in breast cancer cells. Statistic x ... between a and b represents the. probability of that a random variable is in that interval. ...

Mean expression level of BRCA1 gene in breast cancer cells. Statistic x ... between a and b represents the. probability of that a random variable is in that interval. ...

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Inherited Breast and Ovarian Cancer PowerPoint PPT Presentation

Inherited Breast and Ovarian Cancer - Inherited Breast and Ovarian Cancer and Modern Women HGM 2006 - Helsinki 1 June 2006 Common disease - many, individually rare alleles Second, somatic events due to ...

Inherited Breast and Ovarian Cancer and Modern Women HGM 2006 - Helsinki 1 June 2006 Common disease - many, individually rare alleles Second, somatic events due to ...

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The BOADICEA model of genetic susceptibility to breast and ovarian cancer: updating, validation, predictions PowerPoint PPT Presentation

The BOADICEA model of genetic susceptibility to breast and ovarian cancer: updating, validation, predictions - Anglian Breast Cancer Study ... Complex segregation analysis of breast and ovarian cancer ... N. Tang, E. Olah, H. Anton-Culver, E. Warner,J. Lubinski, J. ...

Anglian Breast Cancer Study ... Complex segregation analysis of breast and ovarian cancer ... N. Tang, E. Olah, H. Anton-Culver, E. Warner,J. Lubinski, J. ...

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Prezista ( Darunavir 400mg/Tab ) PowerPoint PPT Presentation

Prezista ( Darunavir 400mg/Tab ) - Title: 1 Last modified by: USER Document presentation format: A3 (297x420 ) Other titles: Arial Calibri Times New Roman DejaVu ...

Title: 1 Last modified by: USER Document presentation format: A3 (297x420 ) Other titles: Arial Calibri Times New Roman DejaVu ...

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Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer PowerPoint PPT Presentation

Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer - Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer MW Audeh,1 RT Penson,2 M Friedlander,3 B Powell,4

Phase II trial of the oral PARP inhibitor olaparib (AZD2281) in BRCA-deficient advanced ovarian cancer MW Audeh,1 RT Penson,2 M Friedlander,3 B Powell,4

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Cancer Risk Assessment PowerPoint PPT Presentation

Cancer Risk Assessment - Cancer Risk Assessment Judith A Westman MD Clinical Director Division of Human Genetics Cancer risk reduction with prophylactic surgery Domchek and Weber, Oncogene ...

Cancer Risk Assessment Judith A Westman MD Clinical Director Division of Human Genetics Cancer risk reduction with prophylactic surgery Domchek and Weber, Oncogene ...

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Diapositiva 1 PowerPoint PPT Presentation

Diapositiva 1 - Com' coinvolta nella risposta agli xenobiotici? ... Helen E. Bryant, Niklas Schultz, Huw D. Thomas, Kayan M. Parker, Dan Flower, ...

Com' coinvolta nella risposta agli xenobiotici? ... Helen E. Bryant, Niklas Schultz, Huw D. Thomas, Kayan M. Parker, Dan Flower, ...

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cancro - Title: Chapter 21: Molecular Basis of Cancer Author: Robert Cramer Last modified by: User Created Date: 8/1/2002 1:28:50 AM Document presentation format

Title: Chapter 21: Molecular Basis of Cancer Author: Robert Cramer Last modified by: User Created Date: 8/1/2002 1:28:50 AM Document presentation format

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Dr. Derakhshandeh, PhD PowerPoint PPT Presentation

Dr. Derakhshandeh, PhD - ... (diagnostic methods) ... mutations where changes are at molecular level Methods for detection of known mutations Methods for detection of unknown mutations ...

... (diagnostic methods) ... mutations where changes are at molecular level Methods for detection of known mutations Methods for detection of unknown mutations ...

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Prostate Cancer - Definition, Symptoms, Causes, Risk Factors, Treatment PowerPoint PPT Presentation

Prostate Cancer - Definition, Symptoms, Causes, Risk Factors, Treatment - Prostate cancer is cancer that occurs in the prostate. The prostate is a small walnut-shaped gland in males that produces the seminal fluid that nourishes and transports sperm.

Prostate cancer is cancer that occurs in the prostate. The prostate is a small walnut-shaped gland in males that produces the seminal fluid that nourishes and transports sperm.

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BRCA Genes - BRCA Genes Dallas Henson BReast CAncer Women have about a 1 in 7 chance of getting breast cancer in their lifetime. Most cancer is sporadic, about 5-10% of cases are ...

BRCA Genes Dallas Henson BReast CAncer Women have about a 1 in 7 chance of getting breast cancer in their lifetime. Most cancer is sporadic, about 5-10% of cases are ...

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cancro - Title: Chapter 21: Molecular Basis of Cancer Author: Robert Cramer Last modified by: User Created Date: 8/1/2002 1:28:50 AM Document presentation format

Title: Chapter 21: Molecular Basis of Cancer Author: Robert Cramer Last modified by: User Created Date: 8/1/2002 1:28:50 AM Document presentation format

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Accessing Genome Annotations - Accessing Genome Annotations

Accessing Genome Annotations

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(tumor suppressor genes ) - : ...

: ...

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Known Causes of Breast Cancer for Women Rock! PowerPoint PPT Presentation

Known Causes of Breast Cancer for Women Rock! - Known Causes of Breast Cancer for Women Rock! Crispin H Pierce, Ph.D. Environmental Public Health Program University of Wisconsin-Eau Claire What is Cancer?

Known Causes of Breast Cancer for Women Rock! Crispin H Pierce, Ph.D. Environmental Public Health Program University of Wisconsin-Eau Claire What is Cancer?

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Genetics and Risk of Breast Cancer PowerPoint PPT Presentation

Genetics and Risk of Breast Cancer - What is the role of mutation testing. What is the risk to ... Assumes single dominantly inherited gene. Assumes one set of penetrance values for a single gene ...

What is the role of mutation testing. What is the risk to ... Assumes single dominantly inherited gene. Assumes one set of penetrance values for a single gene ...

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TUMOR MARKERS PowerPoint PPT Presentation

TUMOR MARKERS - TUMOR MARKERS Dr. Ismet M. Nur Sp.PA (K), MM. Dept. of Pathology Anatomy UNPAD/ Hasan Sadikin Hospital Bandung Tumor markers are : Biochemical indicators of the ...

TUMOR MARKERS Dr. Ismet M. Nur Sp.PA (K), MM. Dept. of Pathology Anatomy UNPAD/ Hasan Sadikin Hospital Bandung Tumor markers are : Biochemical indicators of the ...

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Molecular Markers of Cancer - Molecular Markers of Cancer

Molecular Markers of Cancer

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Familial Cancer PowerPoint PPT Presentation

Familial Cancer - ... -homologous End-joining BRCA function in DNA repair a-Cat b-catenin APC b-catenin b-catenin Actin Transcription MTs E-cadherin Colon gastric * ...

... -homologous End-joining BRCA function in DNA repair a-Cat b-catenin APC b-catenin b-catenin Actin Transcription MTs E-cadherin Colon gastric * ...

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MICB 405 Bioinformatics MiniLab - MICB 405 Bioinformatics MiniLab

MICB 405 Bioinformatics MiniLab

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Genetics of Oncology PowerPoint PPT Presentation

Genetics of Oncology - Describe the clinical relevance of ... Usually act in a recessive fashion ... widely dispersed, but several nations and ethnic groups then to have their own ...

Describe the clinical relevance of ... Usually act in a recessive fashion ... widely dispersed, but several nations and ethnic groups then to have their own ...

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Genetic Screening of Diseases (It PowerPoint PPT Presentation

Genetic Screening of Diseases (It - Genetic Screening of Diseases (It s worth & potential) Dr Derakhshandeh

Genetic Screening of Diseases (It s worth & potential) Dr Derakhshandeh

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PARP Inhibitors: Usurping DNA repair to target cancer PowerPoint PPT Presentation

PARP Inhibitors: Usurping DNA repair to target cancer - PARP Inhibitors: Usurping DNA repair to target cancer Lee Schwartzberg MD, FACP Chief Medical Officer The West Clinic

PARP Inhibitors: Usurping DNA repair to target cancer Lee Schwartzberg MD, FACP Chief Medical Officer The West Clinic

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Hereditary Breast PowerPoint PPT Presentation

Hereditary Breast - Prostate. Pancreas. Mutations in midsection of gene. Increased ovarian cancer ... Increased risk of prostate cancer (8-16%) and male breast cancer ...

Prostate. Pancreas. Mutations in midsection of gene. Increased ovarian cancer ... Increased risk of prostate cancer (8-16%) and male breast cancer ...

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Checkpoints in Mammalian Cells PowerPoint PPT Presentation

Checkpoints in Mammalian Cells - Reduction to Homozygosity in CIN vs MIN Lines. Checkpoints - A Signal Transduction Pathway ... Ataxia Talangiectasis. Cerebellar Ataxia. Talangiectasia ...

Reduction to Homozygosity in CIN vs MIN Lines. Checkpoints - A Signal Transduction Pathway ... Ataxia Talangiectasis. Cerebellar Ataxia. Talangiectasia ...

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Dr Matt Hewitt PowerPoint PPT Presentation

Dr Matt Hewitt - Dr Matt Hewitt Prophylactic Bilateral Salpingoophorectomy * HPV types in cervical cancer This graph shows the cumulative percentages of cervical cancer cases ...

Dr Matt Hewitt Prophylactic Bilateral Salpingoophorectomy * HPV types in cervical cancer This graph shows the cumulative percentages of cervical cancer cases ...

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Hallmarks of Cancer Six fundamental changes PowerPoint PPT Presentation

Hallmarks of Cancer Six fundamental changes - Hallmarks of Cancer Six fundamental changes Self sufficiency in growth factors Insensitivity to growth-inhibitory signals Evasion of apoptosis Limitless replicative ...

Hallmarks of Cancer Six fundamental changes Self sufficiency in growth factors Insensitivity to growth-inhibitory signals Evasion of apoptosis Limitless replicative ...

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HEREDITARY BREAST CANCER IN DEVELOPING COUNTRIES PowerPoint PPT Presentation

HEREDITARY BREAST CANCER IN DEVELOPING COUNTRIES - ... BRCA-1 Cowden s syndrome of multiple hereditary cancers 10q23 (mutated, LOH) PTEN Li-Fraumeni syndrome of multiple hereditary cancers 17p13 (mutated, LOH) ...

... BRCA-1 Cowden s syndrome of multiple hereditary cancers 10q23 (mutated, LOH) PTEN Li-Fraumeni syndrome of multiple hereditary cancers 17p13 (mutated, LOH) ...

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Brca1 PowerPoint PPT Presentations