Chapter 19Microbial Models: The Genetics of Viruses and Bacteria - PowerPoint PPT Presentation

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Chapter 19Microbial Models: The Genetics of Viruses and Bacteria

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Host range: infection of a limited range of host cells (receptor molecules on ... heterotrophic flagellates; Trypanosoma (African sleeping sickness; tsetse fly) ... – PowerPoint PPT presentation

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Title: Chapter 19Microbial Models: The Genetics of Viruses and Bacteria


1
  • Chapter 19 Microbial Models The Genetics of
    Viruses and Bacteria

2
Viral structure
  • Virus poison (Latin) infectious particles
    consisting of a nucleic acid in a protein coat
  • Capsid (viral envelopes) DNA or RNA
  • Bacteriophages (phages)

3
Viral reproduction Lytic Cycle
  • Host range infection of a limited range of host
    cells (receptor molecules on the surface of
    cells)
  • The lytic cycle 1- attachment 2-
    injection 3- hydrolyzation 4- assembly 5-
    release
  • Results in death of host cell
  • Virulent virus (phage reproduction only by the
    lytic cycle)

4
Viral reproduction Lysogenic Cycle
  • Genome replicated w/o destroying the host cell
  • Genetic material of virus becomes incorporated
    into the host cell DNA (prophage DNA)
  • Temperate virus (phages capable of using the
    lytic and lysogenic cycles)
  • May give rise to lytic cycle

5
Lysogenic Cycle
Animation
6
RNA viruses
  • Retroviruses transcribe DNA from an RNA template
    (RNA---gtDNA)
  • Reverse transcriptase (catalyzing enzyme)
  • HIV---gtAIDS

7
Retrovirus (HIV)
  • Animation

8
Viroids and prions
  • Viroids tiny, naked circular RNA that infect
    plants do not code for proteins, but use
    cellular enzymes to reproduce stunt plant growth
  • Prions infectious proteins mad cow
    disease trigger chain reaction conversions a
    transmissible protein

9
Bacterial/Prokaryotic genetics
  • Nucleoid region in bacterium densely packed
    with DNA (no membrane)
  • Plasmids small circles of DNA
  • Reproduction binary fission (asexual)

10
Classification
  • Kingdom Monera?
  • Domain Bacteria
  • Domain Archaea
  • Shape cocci (sphere)
    bacilli (rod) helical (spiral)

11
Form and Function
  • 1- Most have Flagella
  • 2- some are Helical in shape (spirochetes)
  • 3- some produce Slime- used to adhere in masses
  • tooth decay
  • 4-most have some sort of Taxis-movement away or
    toward a
  • stimulus (chemotaxis, phototaxis,
    magnetotaxis)
  • 5-Most have Endospores resistant cells for harsh
    conditions
  • (250 million years!)

12
Animal-like Protist
  • 1- Groups lacking mitochondria early eukaryotic
    link Giardia (human intestinal parasite severe
    diarrhea) Trichomonas (human vaginal
    infection)
  • 2- Euglenoids autotrophic heterotrophic
    flagellates Trypanosoma (African sleeping
    sickness tsetse fly)

13
Animal-like Protist
  • Alveolata membrane-bound cavities (alveoli)
    under cell surfaces dinoflagellates
    (phytoplankton) Plasmodium (malaria)
    ciliates (Paramecium)

14
Plantlike Protist-Algae
  • Rhodophyta red algae no flagellated stages
    phycobilin (red) pigment
  • Chlorophyta green algae chloroplasts gave rise
    to land plants volvox, ulva

15
Funguslike Protist
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