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XIAOHUA
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Title: XIAOHUA Author: user Created Date: 7/1/2003 7:15:29 AM Document presentation format: Company: Other titles: Times New Roman ... – PowerPoint PPT presentation
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Title: XIAOHUA
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?????Antianginal drugs
2
????????
????? ?? ????
?????????
??lt??
3
??????
???????
???????????
??????????
???????
???
4
????????
- ???? (nitrate esters)
- ß????? (ß-Adrenoceptor antagonists)
- ?????? (Calcium antagonists)
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?.????(nitrate esters) ????(nitroglycerin)?????
??(isosorbide dinitrate) ????????(isosorbide
mononitrate)
6
???????? ??????????????? NO?????,?????????,?????
?????
7
??????????????? ??????
???????
????
???
??????????
?????????
8
????????????????????????????
??????
???????????????????????????
9
??????
???
????
????
???
????
10
???
???
??????
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???? (nitroglycerin) ??????, 13???,??0.5??,?????
???? ?? ???? 30 ???,??3 6??,????
12
??????(???) ????? ???????,??????? ???????
????????,??
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???? ???????????? ??????????
?????????????????????????????????????????????,????
???
14
????????????????????????????????????????????????
???????
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ß?????(ß-Adrenoceptor antagonists)
????????????????????????? ß1??????????????????????
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????? ????
??
ß?????
??????
????????????
??????
?? ???
??????
17
???????????????????????,????????????????????????
??.???????????????????
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???? ??????????????????????????
????,??????? ??????????
19
???????????,???????,??????????,??ß????,???????????
???,???????
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??????(Calcium antagonists)
??????,????,????,?????????
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???? 1???????? ??Ca2??,??????,???????????,???
? ??????,???????????
22
2????????? ??????????? ??????? 3?????????
????????
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???? ??????????????????,???????????????????????
???????????
24
????????
ß????????????????????????????????????????????
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??????? ?? ????,?????????
,???????????????????
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??????????
ß???????????
????
??
????
????
????
??
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??? 1. 1.??????????????????? 2. 2.
?????????????????????????????????????????????????
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3.?????ß????????????????????? 4.???????????????
