Title: Respiratory Slide Show
1Respiratory Tract Components
2Respiratory Tract Components in the Bird
lung
3Path of Air into Lungs
Nostrils Nasal Cavity Nasopharynx Larynx
4Formation of the Larynx
5Formation of the Larynx
6Formation of the Larynx
1. Thyroid cartilage 2. Arytenoid cartilage 3.
Cricoid cartilage 4. Interarytenoid muscle
7Formation of the Larynx
1. Vestibule 2. False vocal cord 3. True
vocal cord 4. Trachea
8Path of Air into Lungs
Nostrils Nasal Cavity Nasopharynx Larynx
Trachea Bronchi Bronchioles Alveolii
9Formation of Upper Respiratory Tract
10Lower Respiratory Tract
11Formation of Lower Respiratory Tract
12Formation of Lower Respiratory Tract
13Formation of the Laryngotracheal Tube
14Formation of Lower Respiratory Tract
tracheoesophageal septum
15Formation of the Larynx
16Formation of Lower Respiratory Tract
Recanalization of Larynx
17Formation of Lower Respiratory Tract
Why are some tubes straight and others branched?
18Formation of Lower Respiratory Tract The Role of
Induction
Gut Mesenchyme
Thoracic Mesenchyme
19Formation of Lower Respiratory Tract The Role of
Induction
20Formation of Lower Respiratory Tract The Role of
Induction
21Formation of Lower Respiratory Tract
22Development of Lungs and the Pleura Cavity
23Development of Lungs and the Pleura Cavity
Pseudoglandular phase (5-17 weeks) Further
branching of the duct system (up to 21 further
orders) generates the presumptive conducting
portion of the respiratory system up to the
level of the terminal bronchioles. At this time
the future airways are narrow with little lumens
and a pseudostratified squamous epithelium. They
are embedded within a rapidly proliferating
mesenchyme. The structure has a glandular
appearance. Canalicular phase (15-25
weeks) The onset of this phase is marked by
extensive angiogenisis within the mesenchyme that
surrounds the more distal reaches of the
embryonic respiratory system to form a dense
capillary network. The diameter of the airways
increases with a consequent decrease in
epithelial thickness to a more cuboidal
structure. The terminal bronchioles branch to
form several orders of respiratory bronchioles.
Differentiation of the mesenchyme progresses
down the developing respiratory tree, giving rise
to chondrocytes, fibroblasts and myoblasts.
Terminal sac phase (24-40weeks) Branching
and growth of the terminal sacs or primitive
alveolar ducts. Continued thinning of the stroma
brings the capillaries into apposition with the
prospective alveoli. The prealveoli cells then
flatten, increasing the epithelial surface area
by dilation of the saccules, giving rise to
immature alveoli. By 26 weeks, a rudimentary
though functional blood/gas barrier has formed.
Maturation of the alveoli continues by further
enlargement of the terminal sacs, deposition of
elastin foci and development of vascularised
septae around these foci. The stroma continues
to thin until the capillaries protrude into the
alveolar spaces. Alveolar phase (36 weeks
- term/adult) Maturation of the lung
indicated by the appearance of fully mature
alveoli begins at 36 weeks, though new alveoli
will continue to form for approximately three
years. A decrease in the relative proportion of
parenchyma to total lung volume still
contributes significantly to growth for 1 to 2
years after birth, thereafter all components
grow proportionately until adulthood.
24(No Transcript)
25Pulmonary Vasculature