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Barbara JUROSZEK Institute of Biomedical
Engineering and Instrumentation e-mail
barbara.juroszek_at_pwr.wroc.pl
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NETHERLANDS POLAND
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WROCLAW
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• Founded in 1945
• Faculties 12
• Professors  177   Associate professors
  237
•   Doctors 1 276
• Students 32 000
• 25 various specializations

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• actively participates in international
  co-operation in both education and research
• has the partner universities in Europe, America,
  Asia and Africa
• educates foreigners from 30 countries
• has internationalized its educational programme
  courses offered in English and the credit system
  based on the European Credit Transfer System
  (ECTS) which facilitates the recognition of the
  period of studies in any European country
• issues a diploma with a diploma supplement in
  English

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Biomedical Engineering Education
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Biomedical Engineering Medical Electronics 1st
step General program
KP fundamental KK facultative KS
specialization KNT languages, etc.
MSC work
Internship
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Biomedical Engineering Medical Electronics2nd
step General program
KP fundamental KK facultative KS
specialization KNT languages, etc.
MSC work
Internship
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Faculty of Fundamental Problems of
TechnologyBiomedical Engineering, Medical
Electronics
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Institute of Biomedical Engineering and
Instrumentation Faculty of Fundamental Problems
of Technology Wroclaw University of
Technology Wybrzeze Stanislawa Wyspianskiego 27,
50-370 Wroclaw, Poland
 
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SOME INFORMATION ON ... Institute of
Biomedical Engineering and Instrumentation Facult
y of Fundamental Problems of Technology Wroclaw
University of Technology Wybrzeze Stanislawa
Wyspianskiego 27, 50-370 Wroclaw, Poland
 
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Institute of Biomedical Engineering and
Instrumentation was created in July, 2007 The
Director for the time period 2008-2012 is
Professor Halina Podbielska 27 scientists 20
PhD students
Dozens of students study the Biomedical
Engineering at our Faculty (more than 240 at
the 1. and 2. year)
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The research in fields related to Biomedical
Engineering Biophysics - Biomedical Optics -
Computer Simulations - Medical
Electronics Seven research groups are actively
involved in research projects

• Bio-optics
• Laboratory of Biophysics of Macromolecular
  Aggregates
• Biospectroscopy
• Bioinformatics and Biophysics of Nanopores
• Computer Simulations of Biomedical Systems
• Biomeasurements and Biomedical Signals Analysis
• Biomedical Electronics and Measurements

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Research interests

• Laser applications in medicine
• Optical fibers in medicine
• Photodynamic antibacterial activity
• Bacteria characterization by optical methods
• Photosensitive nanomaterials
• Computer aided analysis of medical images
• Sol-gel based nanomaterials
• Optical and physico-chemical properties of
  different photosensitive dyes entrapped into the
  sol-gel matrices
• Transillumination methods for interphalangeal
  joints diagnosis
• Thermal imaging

1. Bio-Optics Group Group leader Prof. Halina
Podbielska ??? 3 group members   ???? 4 PhD
students
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E. Coli combated with APDT

•  Key competences
• Photodynamic medicine
• Antimicrobial Photodynamic Therapy 
• Photoactive nanomaterials

Bio-Optics Group Group
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•  Key competences
• Sol-gel materials and sol-gel applicators
  for lasertherapies 
• Thermovison for biometrics recognition

Fiberoptic applicator
Tissue coagulation with sol-gel applicators
Biometry by thermal imaging
Bio-Optics Group Group
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•  Key competences
• Transillumination methods for medical
  diagnosis

ill
healthy
Interphalangeal joint
Laser He-Ne
Camera CCD
Bio-Optics Group Group
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Research interests

• Procedures to evaluate sample stability using
  calorimetric methods
• Procedures to evaluate chemical composition of
  complex solid materials using laser induced
  breakdown spectroscopy
• Size and zeta-potential determination using
  dynamic light scattering method
• Study of supramolecular aggregate formation and
  stability
• The study of the effect of physicochemical
  properties of the aqueous phase on the
  supramolecular aggregate formation
• Designing, development and testing of fluorescent
  bio-nano-sensor for High Throughput Screening
  applications

2. Laboratory of Biophysics of Macromolecular
Aggregates Group leader Prof. Marek Langner
???? 4 PhD students
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Research interests

• The influence of near infrared radiation on
  tissue, proteins, nucleotides, and aminoacids by
  means of different spectroscopic methods
• Red blood cells protection by IR irradiation
• Spin labels ESR spectroscopy
• ATR-FTIR and Raman vibrational spectroscopy
• UV-Vis and fluorescence spectroscopy

3. Group of Biospectroscopy Group leader Prof.
Malgorzata Komorowska ? 1 group member   ??? 3
PhD students
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Research interests

• Biological nanopores electropores and protein
  ionic channels
• Conductivity characteristics, structure-function
  relations and medical applications
• Experimental study on electro-nanopores in
  planar lipid membranes
• Electrochemiotherapy of cancer cells in vitro
• Computer modeling of conductivity of various
  nanopores
• Bioinformatical methods for modeling structure of
  membrane channel proteins

4. Group of Bioinformatics and Biophysics of
Nanopores Group leader Prof. Malgorzata
Kotulska ? 1 group member   ?? 2 PhD students
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Research interests

• Biophysics of biological membranes
• Membrane properties modeling by computer
  simulation technique gel-fluid phase transition,
  appearance of ripple phase, membrane permeability
• Interaction between biologically active compounds
  and membranes (anionic and cationic amphiphilic
  compounds) and the influence of molecular probes
  on membrane
• Modeling the influence of lipid oxidation, role
  of antioxidants on membrane electroporation
• Modeling of peristaltic contractions of segments
  of intestine

5. Group of Computer Simulations of Biomedical
Systems Group leader Prof. Krystian
Kubica ??? 3 PhD students
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Research interests

• Neuroscience monitoring, modeling and analysis
  of intracranial pressure, arterial blood pressure
  and cerebral blood flow velocity in patients with
  hydrocephalus
• Pupillometry modeling and clinical applications
  of the eye pupil reactivity
• Tonometry modeling and study of correlation
  between intraocular pressure measurements and
  geometry and biomechanical properties of the
  human eyeball

6. Group of Biomeasurements and Biomedical
Signals Analysis Group leader Dr Henryk
Juniewicz ??? 3 group members   ?? 2 PhD
students
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On-line Infusion Test Analyser
ICP
Notebook
Pressure Sensor
Infusion Pump
Bed-side Monitor
The monitoring of ICP during the infusion test
- estimation of the parameters describing the
compensatory mechanism of the Cerebro
Spinal Fluid system, - decision about the
usage of shunts.
Group of Biomeasurements and Biomedical Signals
Analysis 
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Measurement and analysis of the human pupil
reactivity
Dilators contract
Constrictors contract
Pupil
Pupillary constrictor muscles
Pupillary dilator muscles
The size of the pupil

• Research topics
• analysis of the Pupil Light Reflex taking into
  consideration the intrinisically photosensitive
  Retinal Ganglion Cells
• analysis of the Pupil Spontaneous Fluctuation
  taking into consideration the autonomic nervous
  system activity
• clinical applications of the pupil reactivity
  analysis

Group of Biomeasurements and Biomedical Signals
Analysis 
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Intraocular pressure (IOP) measurement and
modeling of human eyeball
Applanation method of IOP measurement
Eyeball model

• Research topics
• modeling and study of correlation between
  intraocular pressure (IOP) measurement and
  geometry and biomechanical properties of the
  human eyeball
• modeling of the human eyeball with the Finite
  Element Method
• analysis of influence geometry changes after
  LASIK treatment on IOP measurement

Group of Biomeasurements and Biomedical Signals
Analysis 
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Research interests

• Measurement and instrumentation for biomedicine
• Biomedical electronics
• Modeling of biomedical structures and systems
• Acquisition and analysis biomedical of signals
• Electrical impedance spectroscopy and tomography
• Determining elecrolytic conductivity of liquids,
  calculable conductance cell
• Determining of local conductivities in biomedical
  objects
• 3D positioning using magnetic field of low
  frequency for medical applications
• Spirometry
• Measurements of blood pressure

7. Group of Biomedical Electronics and
Measurements Group leader Prof. Zbigniew Moron
?????? ?????? 12 group members   ?? 2 PhD
students
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Babys apnea monitoring system
Accelerometer
Y
X
Z
Signal processing circuit
Early detection of infants apnea under home
conditions allows to decrease the risk of SIDS
and detect some serious illnesses at their early
stage
Group of Biomedical Electronics and Measurements
 
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Auditory Steady-State Responses (ASSR)

• ASSR are used in frequency specific hearing
  threshold estimation
• Several stimuli can be used simultaneously, each
  having different carrier frequency

Group of Biomedical Electronics and Measurements
 
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Magnetic navigation system

• Magnetic navigation system is an useful tool in
  endoscopy and surgery
• Measurements of magnetic induction vector allows
  to determine precise localization of the medical
  instrument inside patients body

Group of Biomedical Electronics and Measurements
 
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Sensors for determining local electrical
conductivity in biological objects
2,0
K/Kinf
sensor tip object environment
1,8
A
B
1,6
C
D
1,4
1,2
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Sample volume
10
100
1000
Compared sensor tip designs
Sensor constant variability caused by changes in
the objects volume
0,16
Conductivity measurement result (S/m)
0,14
0,12
0,1
A
B
0,08
C
D
0,06
E
F
0,04
0,01
0,1
1
Environment conductivity (S/m)
Influence of environment conductivity on the
measurement result
F
E
Active Shield
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Impedance tomography
Group of Biomedical Electronics and Measurements
 
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Spirometry and the respiratory system modeling
Lung airways model
Spirometry - the respiratory system modeling
- errors of measurement in spirometry -
air features in spirometric transducers
Group of Biomedical Electronics and Measurements
 
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Oscillometry blood pressure measurement
Oscillometry - mathematical modeling -
sources of errors in the oscillometric blood
pressure measurements - comparative tests of
the instruments
Blood rpessure monitors comparison
Group of Biomedical Electronics and Measurements
 
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Thank you for your attention