PowerPoint-Pr

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International Vision Correction Research Centre
mike.holzer_at_med.uni-heidelberg.de www.lasik-hd.de
Corneal changes following INTRACOR femtosecond
laser treatment
Mike P. Holzer, MD Annett Mannsfeld, MSc Angela
Ehmer, MSc Gerd U. Auffarth, MD
Study and research has been supported by
Technolas Perfect Vision GmbH, Heidelberg,
Germany
Dept. of Ophthalmology, University of
Heidelberg, Germany Acting chairman G.U.
Auffarth, MD
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Femtosecond Laser Femtec
Femtec (Technolas Perfect Vision GmbH,
Heidelberg, Germany)

• CE mark
• FDA 510k clearance
• 40 kHz

• FEMTEC fixation of eye
• Curved patient interface
• less stress on cornea
• less suction pressure

Mike P. Holzer, MD
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INTRACOR

• Purely intrastromal refractive treatment with
  Femtec Laser
• No cut of epithelium, Bowmans or Descemet
• No incision, pockets etc.
• Cut design and stromal depth algorithm depending
  on refractive error
• Duration approx. 20 seconds

Mike P. Holzer, MD
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Patients Methods

• Ongoing prospective, multicenter study
• Approval of Ethics Committee (Univ. of
  Heidelberg)
• Intrastromal correction of presbyopia
• 25 patients treated between July Sept. 2008
• Age 56.2 5.79 years (range 47 67 years)
• Up to 6 months postoperative follow up
• Minimum near add 2.0 D
• Non dominant eye treated

Mike P. Holzer, MD
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INTRACOR Presbyopia
Mike P. Holzer, MD
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Development near UCVA
n25
n25
n24
n25
n25

p lt 0.01 Friedman-Test
0.7 20/100
0.26 20/30
DCNVA0.23 0.08 logMAR
Mike P. Holzer, MD
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Development near UCVA
preop
3M postop
Mike P. Holzer, MD
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Near and distance visual acuity
Distance correction preop 3M
postop Sphere 0.75 D 0.23 D 0.15 0.31 D
Cylinder -0.33 D 0.17 D -0.42
0.23 D
preop D1 W1 M1 M3
UCDVA 0.11 0.11 0.09 0.10 0.06 0.08 0.06 0.09 0.05 0.10
BCDVA -0.06 0.06 na na -0.02 0.06 0.00 0.07
UCNVA 0.70 0.16 0.39 0.25 0.39 0.22 0.36 0.18 0.26 0.21
DCNVA 0.59 0.12 na na 0.33 0.17 0.23 0.18
BCNVA -0.04 0.08 na na 0.01 0.10 -0.03 0.07
Mike P. Holzer, MD
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Pentacam pre- / 3M postop Exp. 1
Preop 3M postop central steepening
Mike P. Holzer, MD
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Pentacam pre- / 3M postop Exp. 2
Preop 3M postop central steepening
Mike P. Holzer, MD
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Corneal asphericity
Q-value (6.0 mm)
pre anterior pre posterior 1M anterior 1M posterior 3M anterior 3M posterior
Mean value -0.20 -0.34 -0.25 -0.43 -0.26 -0.41
Std. Dev. 0.16 0.16 0.16 0.18 0.18 0.18
? Q-value more negative following INTRACOR
treatment
Mike P. Holzer, MD
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Summary INTRACOR

• High potential for correction of presbyopia
• Non invasive ? very low risk for infections
• Stable refractive outcome during follow up period
• Significant gain in uncorrected near visual
  acuity
• Slight central steepening and negative q-value
• No weakening of cornea
• Future treatments low myopia / hyperopia /
  astigmatism, retreatments of remaining refractive
  errors followingIOL- or Excimer Laser Surgery

Mike P. Holzer, MD