Title: Carcinoma Stomach Carcinoma Colon Pleomorphic Adenoma
1Carcinoma StomachCarcinoma ColonPleomorphic
Adenoma
2- Stomach Cardia
- Fundus
- Body
- Antrum
- Pylorus
- Cells Mucous secreting cells
- Parietal cells or Oxyntic cells
- Chief cells or Peptic cells
- Endocrine cells-G cells
3NORMAL STOMACH
4Gastric fundal mucosa, with short pits lined by
pale columnar mucus cells
5Acute gastric ulcer
6shallow gastric ulcerations known as "stress
ulcers"
7Complications of gastric ulcers (either benign or
malignant) include pain, bleeding, perforation,
and obstruction.
8GASTRIC ULCER
9Helicobacter pylori small curved to spiral
rod-shaped bacterium methylene blue stain
10Tumors of stomach
- Benign tumors Adenomas, Polyps
- Gastric Carcinoma
- - Epithelial
- - Non Epithelial
- - Lymphoma
11Epithelial Malignant Tumors
- Adeno carcinoma
- -papillary
- -Tubular
- -Mucinous
- -Signet ring cell type
- -Undifferentiated
- -Adenosquamous
- -Small cell carcinoma
- -Carcinoid Tumors
12Etiological factors
- H. pylori
- Smoked diet
- Low socioeconomic status
- Cigarette smoking
- Chr. Gastritis
- Barretts esophagitis
- Blood group A
- Family history, HNPCC syndrome
13Gross
- Location
- CLASSIFICATION
- Depth of Invasion
- Macroscopic pattern
- Histologic subtype
14Classification
- Early gastric ca
- Advanced Gastric Ca
- Exophytic growth
- Flat growth
- Excavated growth
- Linitis plastica type
- Intestinal type
- Diffuse type
15Gastric adenocarcinoma.
16Stomach, early carcinoma - Gross, mucosal surface
17Stomach, advanced carcinoma - Gross, mucosal
surface
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19linitis plastica stomach into a shrunken "leather
bottle" appearance.
20Gastric adenocarcinoma has infiltrated through
the wall and appears on the surface as irregular
tan masses.
21moderately differentiated gastric adenocarcinoma
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24Signet ring cell adenocarcinoma
25signet ring cell pattern of adenocarcinoma
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27NORMAL COLON
28POLYPS of COLON
- Non Neoplastic Polyps
- -Hyperplastic polyps
- -Hamartomatous polyps
- -Inflammatory polyps
- -Lymphoid polyps
29Neoplastic Polyps
- Adenomas
- -Villous
- -Tubular
- -Tubulo villous adenomas
- Adeno carcinomas
30Adenomatous polyp
31Adenomatous polyp
32Multiple adenomatous polyps of the cecum
33Familial polyposis coli.
34Familial polyposis coli.
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36 37 38Adenocarcinoma of the colon
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51Pleomorphic adenoma of parotid gland
52Normal salivary gland (submandibular)
53Salivary gland, pleomorphic adenoma - Very low
power
54Pleomorphic adenoma (mixed tumor) of salivary
gland
55Pleomorphic adenoma of parotid gland
Mixed proliferation of both ductal epithelium and
a chondroid/myxomatous stroma
56Epithelial elements dispersed within a background
of loose myxoid tissue containing islands of
fibrocartilage
57THANK YOU