Northern Ireland Clinical Research Networks

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• Northern Ireland Clinical Research Networks
• Judy Bradley PhD MCSP
• Reader in Physiotherapy
• Joint Clinical Lead NICRN (Respiratory Health)

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Objectives

• Background to Clinical Research Networks (CRN)
  and the NICRN
• UKCRC and NICRN
• Infrastructure of NICRN
• Study Adoption
• The NICRN and the AHP Forum

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Why do we need Clinical Research Networks?
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(No Transcript)
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The NICRN

• NICRN Co-ordinating Centre
• Clinical Director
• Senior Manager
• Network Co-ordinators x3

RD Office Funding
NICRN interest groups 9 in total Clinical Lead(s)
Nodes (Trusts) Research Office(s) Research co
ordinators(s) Other supporting staff
CRF
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Components of the NICRN
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NICRN Themed Groups
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Links with the UK
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Functions of NICRN

• Maintain a portfolio of network studies
• Assist with processes involved in setting up a
  study, in particular ethical, regulatory and
  local research governance approval for clinical
  trials
• Communications hub
• Promote the work of the NICRN and disseminate
  NICRN publications and information material.

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Functions contd.

• IT administrative support
• Provision of Training Education
• Proactively manage the topic network budget
  ensuring that research opportunities are
  maximised within available resources

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Staffing Levels
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NICRN Study Adoption Process

• The adoption process is carried out by the
  relevant CMG supported by NICRNCC and in liaison
  with sponsor/PI/CI
• Adoption forms completed by PI and submitted to
  CMG for consideration

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NICRN Study Adoption Process
To be adopted studies must be fully funded

• Studies that are funded by
• A UKCRC partner
• Commercial organisations
• Non-UKCRC partners
• Provided that
• Funding is nationally competitive
• Studies are independently peer reviewed
• Studies fit within remit of a themed group

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Benefits of Adoption

• Coordinated, efficient access to a large and
  diverse patient population across a range of
  clinical services/trusts and demographics
• Add value for both researchers and funders,
  ensuring projects are set up quickly and remove
  the administrative burden for financial, ethics
  and governance arrangements
• NICRN staff assist in recruitment/execution
• Adverse event reporting
• Efficient start up and roll out of studies making
  sure they can be completed on time

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Performance Matrix

• Portfolio of studies
• Accrual
• Timelines (set up, completion)
• Data quality

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Portfolio
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Studies

• Different groups have very different studies
• Commercial Studies vs non commercial studies
• Single site vs multicentre
• Local/National/International studies

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NICRN (Respiratory Health) Clinical Management
Group Members (CMG)

• Co- Leads
• Dr Lorcan McGarvey (Consultant Physician RVH and
  QUB)
• Dr Judy Bradley (Reader in Physiotherapy BCH and
  UUJ)
• Clinical Management Group
• Dr Liam Heany (Consultant Physician, QUB and BCH)
• Prof Stuart Elborn (Consultant Physician, QUB and
  BCH)
• Dr Martin Kelly ( Consultant Physician,
  Altnagelvin)
• Anne Marie Marley (Nurse Consultant, Matter)
• Jackie Meggary (Clinical Physiologist, BCH)
• Dr Joe Kidney ( Consultant Physician, Matter)
• Dr Brenda ONeill (Physiotherapy Lecturer, UUJ)
• Principal Investigators

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The NICRN (Resp Health) Staff

• 3 Staff
• 1 research nurse
• 1 clinical physiologist
• 1 physiotherapist
• Staff currently based at Belfast Trust City
  Hospital Site
• Submitting a proposal for additional staff/?
  Based at other trusts

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The NICRN (Resp Health) Portfolio

• 9 studies adopted (5 in pipeline)
• 8 commericial Studies and 1 non commercial study
  (Charity)
• 1 Single site and 8 multicentre
• 1 Local and 2 UK and 6 International studies

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THE FUTURE.

• Increased participation in studies
• Improved accrual to studies
• Enhanced Communication
• Better Co-ordination of resources
• Consistency of practice performance
• Quality of research
• More patients benefit from clinical research
• Improving the health well being of patients

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The AHP Research Forum and the NICRN

• Getting research supported that is important to
  you
• Get to know key players in research in NI and at
  your site
• Job opportunities within the NICRN
• Opportunity to support national international
  multi-centre trials

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CONTACT DETAILS

• NICRN Co-ordinating Centre
• Room 2007 K.E.B.
• Royal Hospital
• Belfast
• BT12 6BA
• Tel [phone]
• Email

Paul.biagioni_at_belfasttrust.hscni.net
Ciara.mckenna_at_belfasttrust.hscni.net
roisin.Hughes_at_belfasttrust.hscni.net