Title: NIHR Comprehensive Clinical Research Network
1NIHR Comprehensive Clinical Research Network
John Sitzia Senior Assistant Director CCRNUK
Trial Managers NetworkAnnual MeetingThursday
10th April,2008
2UK Health Research Funding
3UK Clinical Research Collaboration
- A partnership of (20) organisations working with
key stakeholders to effect change in UK clinical
RD.
National Institute for Health Research
- An integrated set of funding schemes, systems and
structures established by the Department of
Health to implement the Governments health
research strategy, Best Research for Best
Health.
4Best Research for Best Health
- Sets out five strategic goals in the five-year
plan to create a health research system in which
the NHS supports outstanding individuals, working
in world-class facilities, conducting
leading-edge research focusing on the needs of
patients and the public - 1. Establish the NHS as an internationally
recognised centre of research excellence (NIHR
framework). - 2. Attract, develop and retain the best research
professionals to conduct people-based research. - 3. Commission research focused on improving
health and social care. - 4. Manage our knowledge resources (includes IT).
- 5. Act as sound custodians of public money for
public good.
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6UK Clinical Research Network (UKCRN)
- Aims to develop UK-wide infrastructure embedded
within the NHS to support high quality research
across all areas of health and clinical need
funded by both commercial and non-commercial
funders - Benefits health care, both by improving the
processes of care and by providing new evidence
for better care - Supports excellence and innovation in clinical
research - Closer working between the NHS and industry,
generating national wealth
7NIHR Clinical Research Network (England)
- Six topic specific research networks
- Cancer 33 LRNs (2000, 20M)
- Mental Health 8 LRNs (2003, 4M)
- Diabetes 8 LRNs (2005, 4M)
- - Medicines for Children 6 LRNs (2005, 4M)
- Stroke 8 LRNs (2005, 4M)
- Dementias 7 LRNs (2005, 4M)
- Primary Care Research Network 8 LRNs (2006, 2M)
- Comprehensive Clinical Research Network 25 LRNs
(43M) - Co-ordinating Centre (UKCRN CC, led by clinical
researchers, offices in Leeds and London)
8National coverage for cancer and primary care only
9Comprehensive Clinical Research Network (CCRN)
purposes
- Extends CRN to cover all of England and all
healthcare topics - To facilitate access to NHS patients and research
facilities for NIHR CRN clinical research - To streamline research management processes,
reducing the burden on researchers, whilst
maintaining highest standards - To provide NHS infrastructure through the
allocation and management of funding for NHS
service support, including clinicians time, and
additional NHS clinical services - To signpost investigators to support in
developing and carrying out high quality clinical
research
10NIHR CRN Portfolio
- CRN funding can only be used to support studies
on the NIHR portfolio - National register of all eligible studies
- NIHR Portfolio in England eligibility defined
by DH basic principle is open national
competition and peer review - Portfolios in Northern Ireland, Wales, Scotland
- UK-wide working within portfolios
- Includes multi centre and single centre studies
- Includes commercial and non-commercial studies
- Details of current portfolio available on UKCRN
website (www.ukcrn.org.uk) - Under development!
11Comprehensive Local Research Networks (CLRNs)
structure
- Defined geographically (within SHA boundaries)
and by constituent organisations (providers of
NHS services) - Each CLRN has a resident population of 2M
- Primary, secondary and tertiary care, and mental
health - Led by a Clinical Director (some Co-Directors),
with a supporting management team Executive
Group, Senior Manager, Lead RMG Manager,
Industry Liaison Officer - Network Board (all constituent organisations,
with independent Chair) - Host organisation
- Implementation April 2007 onwards
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13How will CCRN support research?
- Clinical sessions (all professions, all studies)
- Research nurses (CCRN studies, and more
capacity for TCRN/PCRN studies) - Research management (all studies)
- Service support (all studies)
- Key Service Support (especially imaging and
pharmacy) - Routine Service Support
- Funding framework evolving
- per capita population
- activity-based
14John Sitziaj.sitzia_at_ukcrn.org.uk0207 670
4872www.ukcrn.org.uk