PowerPointprsentation

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Cot1- DNA dependent Dyn.Std.Ref.Int. variations
Shown Dynamic Stdandard Reference Interval
Sets 1) Cases having better Cot1-DNA
suppression of test-DNA than of reference-DNA
give Low ratios for 11q13, 16p, 17, 19, 22
and peri-centromeric regions of 1q, 2p, 7, 9,
10p, 13q, 14q, 15q 18p Worst are 19, 17
and 16p 2) Our current routine set of Dynamic
Standard Reference Intervals I.e. cases
having too bad Cot1-DNA suppression or showing
clear imbalance of these do not contribute.
3) Cases having worse Cot1-DNA suppression of
test-DNA than of refeference-DNA give High
ratios for 11q13, 16p, 17, 19, 22 and
peri-centromeric regions of 1q, 2p, 7, 9, 10p,
13q, 14q, 15q 18p Worst are 19, 17 and
16p Note 1 The automatic Cot1-DNA correction
cannot correct for the above special low or high
ratios. Note 2 All sets are scaled automatically
to fit a random case that looks like the routine
set of Std.Ref.Int.
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1) Notice the low ratios of 19, 17 and 16p
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2) Our current routine set
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3) Notice the high ratios of 19, 17 and 16p
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