5 classes of anxiety disorders

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Anxiety disorders

• 5 classes of anxiety disorders
• Generalized anxiety disorder
• Phobias
• Panic Disorders
• Obsessive Compulsive Disorders
• PTSD - post traumatic stress disorder

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• genetic component
• family studies, concordance rates, etc

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Pharmacological Treatments

• 2 major categories for treating anxiety disorders
• BZ (benzodiazepenes)
• 5HT agonists
• adjunctive treatments

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Drug development

• Preclinical testing
• Clinical testing
• Phase 1 safety testing-
• Phase 2 establishing doses
• Phase 3 multi-site double blind placebo
  controlled studies
• Selected populations
• elderly and children