IMMUNE SYSTEM NON-SPECIFIC DEFENSE

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IMMUNE SYSTEMNON-SPECIFIC DEFENSE

• PP. 957-960

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FUNCTION

• Fights pathogens to prevent infections and
  disease
• Works with the lymphatic system (collects fluid
  and returns it to the blood)

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STRUCTURES

• Lymphocytes white blood cells (wbc)
• Bone marrow produces blood cells
• Lymph nodes stores wbc
• Thymus matures wbc
• Spleen contains wbc that clean out pathogens as
  blood filters through

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INITIATING THE IMMUNE SYSTEM

• Antigen any substance that the immune system
  responds to.
• pathogens cause disease
• viruses protein shell containing DNA or RNA
• Bacteria
• Fungi (spores)
• Parasites
• Toxins (snake bites etc)
• Allergens Cause allergies
• Put Your Hands Together

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Nonspecific Defense

• Protects body against any pathogen, regardless of
  the pathogens identity.

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FIRST LINE OF DEFENSE

• Skin
• Block entry
• Toxic-Sweat Oil
• mucous membranes
• Mucous-traps pathogens
• Cilia-moves pathogens out of body
• stomach acids
• destroys pathogens

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SECOND LINE OF DEFENSENon Specific Response

• Inflammatory response
• Injured cells release a chemical signal called
  histamine to increase blood flow to area
• Platelets cause clotting trapping pathogens
• Area swells, becomes warm, and macrophages/phagocy
  te (wbc) move in and engulf bacteria

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SECOND LINE OF DEFENSENon Specific Response

• interferons enzymes that stop virus protein
  production
• fever slow growth of bacteria and increase
  activity of wbc
• Should a fever always be treated? Why or why not?
  

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SECOND LINE OF DEFENSENon Specific Response

• Your body has many different types of lymphocytes
  (WBC)
• Types of Phagocytes (engulf)
• Neutrophils Ingest pathogens
• Macrophage Engulf pathogens other cell debris
• Natural Killer Cells Burst pathogen infected
  cells