ERYTHROPOEISIS

1
ERYTHROPOEISIS
RBC
Basophilic
Polychroma-
Orthochroma-
Hemocytoblast
Proerythroblast
Erythroblast
tophilic
tophilic
Nuclear
Reticulocyte
Erythroblast
Erythroblast
Extrusion
1. dispersed
1. clumped
1. condensed
1. condensed
1. anucleate
Pluripotential
chromatin
eccentric
chromatin
chromatin
Stem Cell
nucleus
2. spherical
2. grey-green
2. nucleoli
2. no
2. pink
cytoplasm
3. slight
nucleoli
cytoplasm
basophilia
(hemoglobin
3. cytoplasmic
3. maximum
(free ribosomes)
synthesis)
basophilia
basophilia
2
Erythropoeisis- Several Stages
3
MYELOPOEISIS
(granulopoeisis)
Hemocytoblast
Myeloblast
(multipotential)
(multipotential)
Promyelocyte
(multipotential)
1. loss of cytoplasmic
basophilia
2. dispersed chromatin
Eosinophilopoeisis
Neutrophilopoeisis
Basophilopoeisis
4
EOSINOPHILOPOEISIS
Eosinophilic
Eosinophilic
Eosinophil
Myelocyte
Metamyelocyte
(band cell)
Specific and
Metachromatic Granules
5
Eosinophilopoeisis- Several Stages
6
NEUTROPHILOPOEISIS
NEUTROPHILIC
NEUTROPHILIC
MYELOCYTE
METAMYELOCYTE
NEUTROPHIL
7
MYELOPOEISIS (Several Stages)

Nutrophilic Band and
Neutrophilic and Eosinophilic Band Cells
Eosinophilic Metamyelocyte
8
BASOPHILOPOEISIS
Basophilic
Basophilic
Myelocyte
Basophil
Metamyelocyte
9
THROMBOPOEISIS
Endomytosis
(w/o karyokinesis
Hemocytoblast
(w/o cytokinesis)
Reserve Megakaryocyte (megakaryoblast)
Platelet-Forming Megakaryocyte
Platelet-Shedding
Residual Megakaryocyte
Platelets
(fusion of
plasma membrane)
10
MEGAKARYOCYTES
11
BONE MARROW
Decalcified Bone and
Marrow
Marrow Cavity
Fat Cells
Bone
12
Marrow
Endothelial Cells
Megakaryocyte
Diapedesis
Adipocyte
Endothelial
Discontinuity
Blood
Sinusoid
Reticular
Hemopoetic
Fibers
Compartment
13
Bone Marrow
Bone Marrow in Decalcified Bone
Bone Marrow Smear