Hypothalamus

1
Hypothalamus
GHRH GHIH TRH -GHIH
GnRH PRH PIH CRH - Dopamine

• Anterior Pituitary Somatotrophs
  Thyrotrophs Gonadotrophs
  Lactotrophs Corticotrophs

hGH TSH
LH FSH PRL
ACTH
Liver, muscle, bone Thyroid
F Ovary F Ovary Mammary
Glands Adrenal Cortex
Cartilage, other cells follicular cells
graafian follicle Primordial follicle
Alveoli zona glomerulosa ?

M Testis M Testis Zona fasciculata
Leydig cells sertoli cells
Causes secretion Causes secretion F
Ovulation F development milk
production secretion of of insulinlike
growth of T3 and T4 Formation of
of 2nd ooctye by breast prepared
glucocorticoids factor
corpus luteum
by progesterone and M secretion
of M secretion of hCS
DHT ABP and sperm- atogensis
2
Growth of body cells, controls BMR, F
estrogen 2nd female sex control
protein catabolism, protein synthesis,
proteins sythesis characterisitcs,
increases Glucose snythesis, lipolysis,
tissue repair, and glucose use, ATP
protein anabolism, lowers increases
resistance toincrease in blood
production, lipolysis, blood cholesterol,
inhibits stress, anti-iflammatory,
inglucose accelerates
growth GnRH, FSH, LH high levels
causes depression F
progesterone synergistic of the immune
responses. with estrogen to
prepare endometrium for implantation, prep
ares mammary gland for milk production,
inhibits GnRH and LH M
Controls male pattern of development,
enlargement of penis and expression of 2nd
sex characteristics, protein anabolism
Insulin-like T3 and T4
F progesterone and estrogen
glucococorticoids growth factor M
Testosterone and DHT