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Death by Bananas

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Hyperkalemia results in: Inhibition of atrial myocardial depolarization. Slowing of heart rate. Prolonging QRS duration; complexes may become bizarre. – PowerPoint PPT presentation

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Title: Death by Bananas


1
Death by Bananas
  • The Management of Hyperkalaemia
  • Dr. Kiaran Flanagan, Clinical Lead Acute Medicine
    UHCW
  • June 2012

2
Case 1
  • Patient comes into ED referred by GP for high
    potassium of 6.7
  • You see the notes in the SIFT tray
  • What do you do? ...

3
How to manage
  • Pick up notes and PUT STICKER ON THE LIST
  • ABCDE
  • What are you likely to find?
  • What urgent investigation do you need to make a
    treatment decision?
  • What action would you take if
  • 1. Normal
  • 2. Abnormal

4
What next?
  • History...
  • Examination...
  • Further tests
  • What are you looking for?

5
What next...
  • Senior review?
  • Actions you should recommend...
  • Drugs
  • Monitoring
  • Admit/ Discharge
  • Further checks
  • Anticipated future actions
  • How will you make this happen?

6
Case 2
  • Patient on the ward
  • ATSP unwell, vomiting
  • Day 2 of admission post op R hemicolectomy
  • What do you do?

7
What do you do?
  • ABCDE
  • Investigations?
  • Monitoring...

8
Patient hyperkalaemic
  • What else do you look for?
  • What test needs to have been done?
  • What treatment do you need to give?

9
Recheck K at 3 hours
  • Still high...
  • What next?
  • Treatment
  • Advice
  • Monitoring

10
Recheck K at 6 hours
  • Still high...
  • What do you do?
  • Treatment
  • Monitoring
  • Ask for help
  • Who
  • What will you tell them and how?
  • What for

11
Case 3
  • Patient Medical ALERT to Resus
  • Drowsy
  • High glucose
  • What do you do????

12
What do you do?
  • ABCDE
  • Urgent tests
  • What is the diagnosis?
  • How do you manage?

13
Case 4
  • Cardiac Arrest Call
  • PEA
  • What do you think about?

14
Hyperkalaemia in cardiac arrest
  • What do you give?

15
Case 5
  • Called to ward 1, pt unwell
  • Low BP, low glucose, high potassium
  • What do you do?
  • Assessment
  • Further tests?
  • Working diagnosis
  • Treatment?

16
Causes of Hyperkalaemia
  • Decreased or impaired potassium excretion renal
    failure, potassium-sparing diuretics, urinary
    obstruction, sickle cell disease, Addison
    disease, and systemic lupus erythematosus (SLE)
  • Additions of potassium into extracellular space -
    potassium supplements (eg, PO/IV potassium, salt
    substitutes), rhabdomyolysis, and hemolysis (eg,
    blood transfusions, burns, tumor lysis)
  • Transmembrane shifts (ie, shifting potassium from
    the intracellular to extracellular space) -
    acidosis and medication effects (eg, acute
    digitalis toxicity, beta-blockers,
    succinylcholine)
  • Factitious or pseudohyperkalemia - improper blood
    collection (eg, ischemic blood draw from
    venipuncture technique), laboratory error,
    leukocytosis, and thrombocytosis

17
Causes
  • Ineffective elimination
  • Kidneys
  • Drugs
  • Endocrine
  • Excessive release from cells
  • Injury
  • Metabolic
  • Excessive intake
  • Lethal Injection
  • Pseudo

18
ECG Changes
19
How does it affect the heart?
  • Hyperkalemia results in
  • Inhibition of atrial myocardial depolarization.
  • Slowing of heart rate.
  • Prolonging QRS duration complexes may become
    bizarre.
  • Also known as atrial standstill.
  • Rhythm called sinoventricular rhythm.
  • The ECG is a poor substitute for serum potassium
    levels to determine the degree of abnormality

20
ECG Changes
  • From reduction of P wave amplitude and
    prolongation of PR interval to absence of P waves
    altogether.
  • Increase of QRS duration.
  • Increase of QT duration.
  • Slowing of heart rate.
  • T waves become tall and spiked.
  • Decreased R wave amplitude

21
ECG Changes
22
3 Principles of Treatment
  • Stabilise myocardium
  • Move it into cells
  • Increase elimination

23
Dextrose - Insulin
  • How does it work?
  • How long for?
  • How do you give it?
  • What is the dose?
  • Other considerations...

24
Calcium Gluconate
  • How does it work?
  • How long for?
  • How do you give it?
  • What is the dose?
  • Other considerations...

25
Sodium Bicarbonate
  • How does it work?
  • How long for?
  • How do you give it?
  • What is the dose?
  • Other considerations...

26
Calcium Resonium
  • Hmmm....

27
More controversial
  • Salbutamol
  • Furosemide

28
Protocols
  • If K gt 6 mmol
  • Calcium Resonium
  • Unless Rising fast/ patient septic then treat
    as below
  • If K gt 6.5 normal ECG
  • Dextrose Insulin
  • Calcium Resonium

29
Protocols
  • If K gt 6.5 abnormal ECG or
  • If K gt 7
  • Calcium Gluconate
  • Dex Insulin
  • Salbutamol
  • Sodium Bicarbonate
  • RRT

30
Important Bits...
  • POTENTIAL LIFE THREATENING EMERGENCY
  • TREAT IF INDICATED
  • TRUST BUT VERIFY
  • RECHECK
  • CARDIAC MONITORING
  • EXPERT HELP
  • PREVENTION
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