Role of Angiogenesis in Primary and Metastatic Tumors

1
Role of Angiogenesis in Primary and Metastatic
Tumors
2
Survival Correlation With Blood Vessel Number
and VEGF Levels
Adapted with permission from Takahashi et al.
Arch Surg. 1997132541.
3
Metastasis Correlation With Blood Vessel Number
and VEGF Levels
Adapted with permission from Takahashi et al.
Cancer Res. 1995553964.
4
VEGF and Angiopoietin Families Ligands and
Receptors
Adapted with permission from Gale and
Yancopoulos. Genes Dev. 1999131055.
5
Maturation of the New Tumor Vessel
6
Growth Factor Regulation of Angiogenesis
7
Strategies to Inhibit Tumor Angiogenesis
Adapted with permission from Fidler et al. In
DeVita et al. Cancer Principles and Practice of
Oncology. 6th ed. 2001137.
8
Antiangiogenic Therapy Efficacy
9
Traditional vs Antiangiogenic Anticancer Therapy
Effect on Tumor
10
Theoretical Angiogenic Profile of Organ
Metastases
Jung et al. Cancer Metastasis Rev. 200019147.