Title: National Institutes of Health SMALL BUSINESS FUNDING OPPORTUNIHTIES
1National Institutes of Health SMALL BUSINESS
FUNDINGOPPORTUNIHTIES
Jo Anne Goodnight NIH SBIR/STTR Program
Coordinator Phone 301-435-2688 Fax
301-480-0146 Email jg128w_at_nih.gov
2Research Opportunities Reserved for Small
Business
SMALL BUSINESS INNOVATION RESEARCH (SBIR)
PROGRAM SMALL BUSINESS TECHNOLOGY TRANSFER
(STTR) PROGRAM
Updated 07/07/05 (KE)
3SBIR/STTR A Three Course Overview
Course 101 SBIR/STTR Basics Course 102 NIH
SBIR/STTR Features and Nuances Course
103 Transitioning to the Marketplace Final Exam
4Course 101 SBIR / STTR Learn the
Basics General Features and Agency Nuances
5SBIR / STTR Program Mission
Supporting scientific excellence and
technological innovation through the investment
of federal research funds in critical American
priorities to build a strong national economy
one small business at a time.
6Program Descriptions and Goals
- Small Business Innovation Research (SBIR)
Set-aside program for small business concerns to
engage in federal RD -- with potential for
commercialization.
- Stimulate technological innovation
2.5
- Foster and encourage participation by minorities
and disadvantaged persons in technological
innovation
- Increase private-sector commercialization of
innovations derived from Federal RD
Small Business Innovation Development Act of 1982
7Program Descriptions and Goals
- Small Business Technology Transfer (STTR)
Set-aside program to facilitate cooperative RD
between small business concerns and U.S. research
institutions -- with potential for
commercialization.
- Stimulate and foster scientific and technological
innovation through cooperative research
0.30
- Foster technology transfer between small business
concerns and research institutions
Small Business Research and Development Enhancemen
t Act of 1992
8SBIR / STTR Participating Agencies
- DOD SBIR/STTR
- HHS SBIR/STTR
- NASA SBIR/STTR
- DOE SBIR/STTR
- NSF SBIR/STTR
- DHS SBIR
- USDA SBIR
- DOC SBIR
- ED SBIR
- EPA SBIR
- DOT SBIR
9Were all just a little bit different ...
10SBIR/STTR 3-Phase Program
- PHASE I
- Feasibility Study
- 100K and 6-month (SBIR)
- or 12-month (STTR) Award
- PHASE II
- Full Research/RD
- 750K and 2-year Award
- (SBIR/STTR)
- PHASE III
- Commercialization Stage
- Use of non-SBIR/STTR Funds
11SBIR PROGRAM ELIGIBILITY CHECKPOINTS
- Organized for- profit U.S. business
- At least 51 U.S.- owned by individuals and
independently operated - Small Business located in the U.S.
- 500 or fewer employees
- P.I.s primary employment with small
- business during project
12STTR PROGRAM ELIGIBILITY CHECKPOINTS
- Applicant is Small Business Concern
-
- Formal Cooperative RD Effort
- Minimum 40 by small business
- Minimum 30 by U.S. research institution
- U.S. Research Institution
- College or University other non-profit
research - organization Federal RD center
- Intellectual Property Agreement
- Allocation of Rights in IP and Rights to Carry
out - Follow-on RD and Commercialization
13SBIR / STTR ELIGIBILITY OWNERSHIP AND CONTROL
got questions?
- Contact the SBA Size Specialists
- Request an eligibility determination
- http//www.sba.gov/size/indexcontac
ts.html
14SBIR AND STTR PROGRAMSCRITICAL DIFFERENCES
- Research Partner
- SBIR Permits research institution partners
- Outsource 33 Phase I and 50
Phase II RD - STTR Requires research institution partners
(e.g., universities) - 40 small business concerns
(for-profit) and - 30 U.S. research institution
(non-profit)
AWARD ALWAYS MADE TO SMALL BUSINESS
15SBIR AND STTR PROGRAMSCRITICAL DIFFERENCES
- Principal Investigator
- SBIR Primary (gt50) employment must be with
small business concern - STTR Primary employment not stipulated
- PI can be from research institution
and/or - from small business concern
DISCUSS WITH AGENCIES
16STTR RESEARCH INSTITUTION PARTNER
- Non-profit organization owned and operated
exclusively for scientific or educational
purposes - Non-profit medical and surgical hospitals
- eligible as partner as long as these
institutions are exclusively engaged in
scientific research and/or application of
scientific principles and techniques
17STTR RESEARCH INSTITUTION PARTNER
- Formal collaborative relationship with SBC
- Perform minimum of 30 of the research/RD
(maximum 60)
18PI Eligibility on STTR
- Formal collaborative relationship PI at RI
- establishes contract between RI and SBC
- describing PIs involvement
- PI is NOT required to be employed by SBC
- Minimum 10 effort
- PI and co-investigator must be paid at either
- SBC or RI , but NOT BOTH
- PIs signature on Face Page is agreement to
- conforming to Solicitation requirements
19FEE/PROFIT
- Up to 7 of total direct and FA costs may
- be requested for fee
- Must be REQUESTED/JUSTIFIED in application
- Does not need to be negotiated
- Only SBC eligible no contracts, consortium or
other third party are eligible for fee - Not direct or indirect cost
20PERFORMANCE of RESEARCH ACTIVITIES
- All research/RD must be performed in its
entirety in the U.S. - Rare cases to conduct testing of specific
- patient populations allowable
- Travel to scientific meeting in foreign
- country allowable
- Foreign consultants/collaborators allowable,
- but must perform consulting in U.S.
21Important Facts to Remember
- Eligibility is determined at time of award
- No appendices allowed in Phase I
- The PI is not required to have a Ph.D.
- The PI is required to have expertise to oversee
- project scientifically and technically
- Applications may be submitted to different
- agencies for similar work
- Awards may not be accepted from different
- agencies for duplicative projects
22Course 102 The NIH SBIR/STTR Program Features
and Nuances
23 THE NIH SBIR/STTR PROGRAM FEATURES and NUANCES
- NIH Mission
- Whats New?
- Budget and
- Award Amount
- Award Type
- Solicitations
- Receipt Dates
-
- Research Topics
- Application Process
- Gap Funding
- Funding Trends
- Website
- Resource Toolbox
24NIH Mission
IMPROVE HUMAN HEALTH through biomedical and
behavioral research, research training and
communications.
25AN ADDED DIMENSION TO THE NIH CULTURE
The National Institutes of Health needs to work
much more closely with industry to find cures for
disease and improve global health and will
aggressively seek out partnerships with private
companies. -- Dr. Elias Zerhouni
NIH Director
26National Institutes of Health
http//www.nih.gov/icd/
Office of the Director
National Institute on Alcohol Abuse and Alcoholism
National Institute of Arthritis
and Musculoskeletal and Skin Diseases
National Cancer Institute
National Institute on Aging
National Institute of Child Health and
Human Development
National Institute of Allergy and Infectious
Diseases
National Institute of Dental and Craniofacial Rese
arch
National Institute of Diabetes and Digestive
and Kidney Diseases
National Institute on Drug Abuse
National Institute of Environmental Health
Sciences
National Institute on Deafness and
Other Communication Disorders
National Eye Institute
National Human Genome Research Institute
National Heart, Lung, and Blood Institute
National Institute of Mental Health
National Institute of Neurological Disorders
and Stroke
National Institute of General Medical Sciences
National Institute of Nursing Research
National Center on Minority Health and Health
Disparities
National Institute of Biomedical Imaging and
Bioengineering
National Center for Complementary and
Alternative Medicine
National Library of Medicine
Fogarty International Center
National Center for Research Resources
Largest SBIR/STTR set-asides
27National Institutes of Health
http//www.nih.gov/icd/
Office of the Director
National Institute on Alcohol Abuse and Alcoholism
National Institute of Arthritis
and Musculoskeletal and Skin Diseases
National Cancer Institute
National Institute on Aging
National Institute of Child Health and
Human Development
National Institute of Allergy and Infectious
Diseases
National Institute of Dental and Craniofacial Rese
arch
National Institute of Diabetes and Digestive
and Kidney Diseases
National Institute on Drug Abuse
National Institute of Environmental Health
Sciences
National Institute on Deafness and
Other Communication Disorders
National Eye Institute
National Human Genome Research Institute
National Heart, Lung, and Blood Institute
National Institute of Mental Health
National Institute of Neurological Disorders
and Stroke
National Institute of General Medical Sciences
National Institute of Nursing Research
National Center on Minority Health and Health
Disparities
National Institute of Biomedical Imaging and
Bioengineering
National Center for Complementary and
Alternative Medicine
National Library of Medicine
Fogarty International Center
National Center for Research Resources
Largest SBIR/STTR set-asides
28NIH SBIR/STTR ProgramWhats New?
- Electronic Submissions December 1 receipt date
- Register in NIH Commons grants.gov
- Modular budgets no longer accepted
- Clarification of Instructions for Preparing Human
Subjects Section of Research Plan - FDA Resources and Useful Websites
- Subsidiary eligibility
- Technical Assistance Programs
29New Public Access Policyto Publications
Resulting from NIH-funded Research
- NIH-funded investigators are requested to submit
to the NIH National Library of Medicine's (NLM)
PubMed Central (PMC) an electronic version of the
author's final manuscript upon acceptance for
publication, resulting from research supported,
in whole or in part, with direct costs from NIH.
Effective May 2, 2005
NIH Guide, February 3, 2005 http//grants1.nih.gov
/grants/guide/notice-files/NOT-OD-05-022.html
30Why Public Access?
- ACCESS Provide electronic access to NIH-funded
research publications for patients, families,
health professionals, teachers, and students. - ARCHIVE Keep a central archive of NIH-funded
research publicationsfor now and in the future,
preserving vital medical research results and
information for years to come. - ADVANCE SCIENCE Create an information resource
that will make it easier for scientists to mine
medical research publications, and for NIH to
better manage its entire research investment.
31What to Submit for the Public Access Policy
- The Policy applies to peer-reviewed, original
research publications that have been supported in
whole or in part with direct costs from NIH. It
does not apply to book chapters, editorials,
reviews, or conference proceedings. - The Policy applies to all research grant and
career development award mechanisms, cooperative
agreements, contracts, Institutional and
Individual Ruth L. Kirschstein National Research
Service Awards, as well as NIH intramural
research studies. - NIH is requesting that authors submit manuscripts
resulting from - currently funded NIH research projects or
- previously supported NIH research projects where
manuscripts were accepted for publication on or
after May 2, 2005. - Publications resulting from non-NIH-supported
research projects should not be submitted.
32NIH SBIR/STTR ProgramReminders
- Similar, Essentially Identical or Identical
Applications to NIH awarding components (ICs) NOT
allowed - Submission Dates Postmark Date acceptable for
applications submitted in response to PHS 2005-2 - Dun and Bradstreet (DB) Data Universal Numbering
System (DUNS) number is required - Type 2 Competing Continuation Ph II Awards
33Budget and Award Amount
640
Propose a Realistic and Appropriate Budget
for the Research Take Home Message 1
34Types of SBIR / STTR Awards
- GRANTS You decide the research and product to be
designed or developed (SBIR / STTR) - CONTRACTS The government decides the research
and general product to fill their perceived need
(SBIR only) - COOPERATIVE AGREEMENTS Similar to grants, but
awarding IC has substantial involvement in
carrying out the project's activities.
95
4-5
lt1
35 SOLICITATION RECEIPT DATES
SBIR/STTR Omnibus Grant Solicitation (NIH, CDC
and FDA)Release January Receipt Apr 1, Aug 1,
Dec 1
Contract Solicitation Release August Receipt
November (2nd Friday) NIH Guide Release
Weekly Receipt Dates as noted
36NIH SBIR/STTR RESEARCH AREAS
Angioscopes to Zebrafish
37NIH SBIR/STTR RESEARCH GRANT TOPICS
Our ideas .(examples)
- Biodefense
- Biosensors
- Nanotechnologies
- Bioinformatics
- Behavioral research
- Computational Biology
- Telehealth
- Biosilicon devices
- Biocompatible materials
- Acousto-optics /opto-electronics
- Imaging technologies
- Genetically engineered proteins
- Proteomics / Genomics
- Complementary and Alternative Medicine
-
38NIH SBIR/STTR RESEARCH GRANT TOPICS
Your ideas...
- Investigator-initiated RD
- Research topics related to the NIH mission
- Other areas of research within the
- mission of an awarding component
-
Take-home Message 2
39DOES MY TECHNOLOGY FIT IN NIH?
See Mission Statement!
Solution to Real Problem. that affects Real
People!
40NIH Guide for Grants ContractsSpecial
SBIR/STTR Opportunities
http//grants.nih.gov/grants/guide/index.html
Go Beyond the SBIR/STTR Omnibus Solicitation.
41NIH GUIDE PAs and RFAs SBIR/STTR Opportunities
42SBIR/STTR Tip of the RD Iceberg
2.8
NIH Extramural Research Budget
43Grant Application Process
44 NIH SBIR/STTR PROGRAM Application Process for
Research Grant
45Grant Application AssignmentWhat if I cannot
determine which IC is most appropriate?
46Application Assignments
- Scientific Review Groups
- NIH Center for Scientific Review RECEIPT and
REFERRAL STAFF refer applications to an Initial
Review Group and Study Section -
- Match between research and scientific review
group within IRG - Scientific expertise/specialization
- Special Emphasis Panels, Ad hoc Not Chartered
- Institutes/Centers
- NIH Center for Scientific Review RECEIPT and
REFERRAL STAFF refer applications to Institute or
Center as the potential funding component - Match between research proposed and ICs mission
- Multiple IC assignments when technologies
cross-cut more than one IC
47 Applications Submitted to NIH Center for
Scientific Review REGARDLESS OF
INSTITUTE/CENTER TOPIC LINKAGE
Cover Letter A Valuable Tool
- Suggest potential awarding component(s)
- Discuss areas of expertise appropriate for the
applications review - Indicate individual(s) or organization(s) in
conflict
48 NIH SBIR/STTR PROGRAM Review Process for
Research Grant
Submits SBIR/STTR Grant Application to NIH
2-3 months after submission
2-3 months after review
IC Staff Prepare funding Plan for IC Director
Grantee Conducts Research
49Peer Review of SBIR/STTR Grant Applications
50Streamlined Procedures of NIH Grant Application
Review
- Reviewers
- Rate applications upper half and lower half
- Discuss at review applications identified between
100 and 300 - Triage/ UNscore applications between
- 300-500. generally
- Applicants ALL
- Automatically receive essentially verbatim
- written critiques (Summary Statement)
51Review Criteria
1. Significance 2. Approach 3. Innovation 4.
Investigators 5. Environment Protection of
Human Subjects Animal Welfare Budget
Program staff do NOT participate in peer review
process
STUDY SECTIONS DO NOT FUND!
52HINT!
Research Plan should include answers to questions
described under Review Criteria! (See
Solicitation)
53NIH REVIEW CRITERIA (Phase II)
- See Previous Slide
- Demonstrated Feasibility in Phase I
- Commercialization Plan
- High Degree of Commercial Potential based on
Commercialization Plan - Protection of Human Subjects
- Animal Welfare
- Budget
54Phase II Commercialization Plan
Included in ALL Phase II applications. Detailed
instructions provided.
- Value of the SBIR/STTR Project, Expected
Outcomes, and Impact - Company Description
- Market, Customer, and Competition
- Intellectual Property (IP) Protection
- Finance Plan
- Production and Marketing Plan
- Revenue Stream
55Post Review Next Steps
- Read the summary statement
- Re-read the summary Statement
- Contact your Program Director
- Guidance and advice
- Discuss options
56Common Problems with Applications
- Inadequately defined test of feasibility
- Diffuse, superficial, or unfocused research plan
- Lack of sufficient experimental detail
- Questionable reasoning in experimental approach
- Uncritical approach
- Failure to consider potential pitfalls and
alternatives - Lack of innovation
- Unconvincing case for commercial potential or
societal impact - Lack of experience with essential methodologies
- Unfamiliar with relevant published work
- Unrealistically large amount of work proposed
57NIH Allows Amended Applications
- Two amended applications allowed
- Generally half of the reviewers are new
- Request for change of reviewers must be supported
- An opportunity to revise and improve your
application
58 NIH SBIR/STTR APPLICATION PROCESS TIMELINE
2-tiered review process
SBIR/STTR Scientific/Technical Adv
Council Est.Award Receipt
Dates Peer Review Board Review
Date Apr 1 June/July Sept/Oct
Dec Aug 1 Oct/Nov Jan/Feb
Mar Dec 1 Feb/March May/June
July
7 9 months
90-Day pre-award costs are allowable At your
own risk..
59SBIR Funding Trends
2000 - 2004
Success Rate ()
60STTR Funding Trends
2000 - 2004
Success Rate ()
61NIH SBIR/STTR AWARD PROCESS
Congratulations!The check is in the mail
(almost)
62NIH SBIR/STTR AWARD PROCESS Avoid Delays
- Human Subject Issues (OHRP)
- IRB and Assurances
- http//ohrp.osophs.dhhs.gov/index.htm
- Animal Welfare Issues (OLAW)
- IACUC (Animal Involvement)
- http//grants.nih.gov/grants/olaw/olaw.htm
- EIN (Entity Identification Number)
- http//www.irs.gov
- DUNS Number
- Third Party Involvement
- Contracts, Consortia, Consultants
63 Gap Funding Options
Phase I
Phase II
64NIH SBIR/STTR ProgramGap Funding Options
- Phase I / Phase II Fast Track
- Simultaneous submission / concurrent review
-
- No-Cost Extension (Ph I or Ph II)
- Extension in time with no additional funds
-
- Administrative / Competitive Supplements
- Discuss with Program Director
-
65NIH SBIR/STTR FAST-TRACK Bridging the Funding Gap
Phase I Completed Submit satisfactory Phase I
Final Report
Discuss Fast-Track Option with Program Director
66NIH SBIR FAST-TRACK Best Option For Everyone?
No!
- Convincing preliminary data?
- Clear, measurable, achievable milestones?
- Well-conceived Commercialization Plan?
- Letters of Phase III support/interest?
- Track record for commercializing?
-
Discuss Fast-Track Option with Program Director
67Course 103 Transitioning to the Marketplace
68 Transitioning SBIR / STTR Projects to the
Marketplace
Phase I
Phase II
Phase III
69CommercializationA Magic Formula?
- Phase I Phase II Phase III
- Typical for SBIR/STTR Projects that do not
require clinical evaluation - Phase I Phase II ? Phase III
- Typical for SBIR/STTR Projects that require
clinical evaluation and FDA approval
70Commercialization Issues
- Phase II to Phase III Pier or Mountain?
- Clinical evaluation and FDA approvals
- cGMP and GLP Facilities
- Partnerships and Strategic Alliances
- Drugs and Biologics require vast amounts of time
and - Average of 8.5 years
- (lab research/animal testing to clinical
trials) - Average of 1.6M
71http//www.fda.gov/cder/handbook/Develop.gif
- NDA Contains
- Pre-clinical studies
- Human clinical studies
- Manufacturing Details
- Labeling Info
- Other Info
72InNIHovative Solutions to Commercialization
Issues
Competing Continuation Phase II Award
From the Test Tube to the Medicine Cabinet
73Competing Continuation Phase II Award Purpose
- To take existing, promising compounds developed
under a Phase II through the next step of drug
discovery and development.
- Provide additional Phase II research support to
continue assessing and improving devices or
conducting preclinical studies of drugs or
devices that ultimately require - clinical evaluation
- approval of a Federal regulatory agency
- refinements to durable medical equipment (DME)
- designs
74Competing Continuation Phase II Award Eligibility
- SBIR Phase II awardee
- Promising pharmacologic agents or devices have
already been identified (or developed) and some
preclinical pharmacology has been conducted. - Response to an NIH Announcement
- Generally, 750k-1M/year for up to 3 years
Contact your Program Director to discuss!
75Competing Continuation Phase II
Award Participating ICs
NIMH NICHD NCI NIAAA
NHLBI NIDA NIAID NINDS
NIDCD NIA NIDDK
See http//grants.nih.gov/grants/funding/sbir_an
nouncements.htm
See PHS 2004-2 SBIR/STTR Grant Solicitation,
Part II
76Technical Assistance Programs
Business strategic planning Builds alliances
and investor partnerships
- Commercialization
- Assistance
-
(Phase II awardees)
Identify other uses of technology Determines
competitive advantages Develops market entry
strategy
Pilot Niche Assessment
(Phase I awardees)
More tomorrow
77SBIR / STTR Toolbox Information and Resources
78INFORMATION and RESOURCES A GOOD STARTING POINT
- NIH SBIR / STTR Grant Solicitation, Forms and
Instructions - http//grants.nih.gov/grants/funding/sbir.ht
msol - Contacts at NIH
- http//grants.nih.gov/grants/contacts.htm
- National SBIR / STTR Resource Center
- http//www.sbirworld.com
79INFORMATION and RESOURCESFINDING A PARTNER
- CRISP Award Database
- http//crisp.cit.nih.gov
- NIH Collaboration Opportunities and Research
Partnerships - http//grants.nih.gov/grants/funding/corp.htm
- NIH Office of Technology Transfer
- http//ott.od.nih.gov/
80INFORMATION and RESOURCES FINDING A PARTNER
(cont)
- Federal Laboratory Consortium for Technology
- Transfer
- http//www.federallabs.org/
- State SBIR/STTR Support
- http//www.sbirworld.com/statecontacts.asp?mnuSta
te1
81Key to the NIH Application, Review, and Award
Process
Communication
82http//www.nih.gov
Visit the NIH Small Business Funding
Opportunities Website
83http//grants.nih.gov/grants/funding/sbir.htm
84Contact NIH Staff Program Staff Pre-
Application
Assess the fit Whats New PAs/RFAs Assist in
finding collaborators Review Issues Dos and
Donts Define product and focus application
Application
Review
Award
85Contact NIH Staff Program Staff Post Review
- Discuss outcome of peer review
- Review Summary Statement
- What the rating means (numeric vs. )
- Strengths and weaknesses
- Likelihood of funding
- Next steps
If at first you dont succeed.
Revise and resubmit
Application
Review
Award
86Contact NIH Staff Review Staff
- Scientific Review Administrator.
- Point of contact during review process
- Recruitment/Assignment of Reviewers
- Concerns about I/C Assignment or Review
Review
87Contact NIH Staff Grants Management Staff
- Pre-Award Steps
- Post-Award Advice Guidance
Award
88 Were from the Government, and were here to
help you.
Final Take-home Message
89National Institute of Environmental Health
Sciences
Fogarty International Center
National Institute on Aging
National Institute of Diabetes and Digestive
and Kidney Diseases
National Cancer Institute
National Institute of Child Health and
Human Development
National Eye Institute
National Institute of Biomedical Imaging and
Bioengineering
National Institute on Drug Abuse
National Institute of Dental and Craniofacial Rese
arch
National Human Genome Research Institute
National Institute of Arthritis
and Musculoskeletal and Skin Diseases
National Institute of General Medical Sciences
National Institute of Mental Health
National Institute of Nursing Research
National Center for Research Resources
National Heart, Lung, and Blood Institute
National Institute on Deafness and
Other Communication Disorders
National Institute of Allergy and Infectious
Diseases
National Institute of Neurological Disorders
and Stroke
National Library of Medicine
National Center on Minority Health and Health
Disparities
National Institute on Alcohol Abuse and Alcoholism
National Center for Complementary and
Alternative Medicine
New!
Largest SBIR/STTR set-asides
90National Institutes of Health
http//www.nih.gov/icd/
Office of the Director
National Center on Minority Health and Health
Disparities
91Final Exam The Top 10 List
92Top 10 Reasons to Seek SBIR / STTR Funding
Opportunities
10. 2.2 Billion available
9. NOT A LOAN - no repayment
8. Provides recognition, verification and
visibility
7. Potential leveraging tool to
attract venture capital/other sources of
93Top 10 Reasons to Seek SBIR / STTR Funding
Opportunities
6. Fosters partnerships (e.g., large
corporations, academia)
5. Stimulates local and state
economies stronger national economy
4. Provides seed money to fund high risk
projects
94Top 10 Reasons to Seek SBIR / STTR Funding
Opportunities
3. Intellectual property rights are normally
retained by the small business
- 2. Small business concerns are
- recognized as a unique national
- resource of technological
- innovation
95Top 10 Reasons to Seek SBIR / STTR Funding
Opportunities
1. To make economic and societal
contributions to America
96Jo Anne Goodnight NIH SBIR/STTR Program
Coordinator Phone 301-435-2688 Fax
301-480-0146 Email jg128w_at_nih.gov
Kay Etzler NIH SBIR/STTR Program Phone
301-435-2713 Email etzlerk_at_od.nih.gov
Kathleen Shino Acting NIH SBIR/STTR Program
Coordinator Phone 301-435-2689 Email
shinok_at_mail.nih.gov
97Innovations that can change the way we work,
think and live.
SBIR/STTR