NIAID-Biodefense Proteomics Research Programs

1
NIAID-Biodefense Proteomics Research Programs
Peter McGarvey, Raja Mazumder, Hongzhan Huang,
Jian Zhang and Cathy Wu Protein Information
Resource, Georgetown University, Washington, DC
20007
Abstract The National Institute for Allergy and
Infectious Diseases (NIAID) has created a
biodefense proteomics program with the goal to
identify and validate therapeutic drug targets
for the next generation of vaccines,
therapeutics, and diagnostics for agents of
concern in bioterrorism. The program consists of
seven Proteomics Research Centers and an
Administrative Resource Center. In addition to
administrative support, the Admin Center is
developing a bioinformatics infrastructure that
includes a web portal for public dissemination, a
central proteomic database hosting the data and
technology protocols generated by each Proteomics
Center, and a protein knowledge system for data
integration, data mining and data analysis.
U of Michigan
Albert Einstein
PNNL
Harvard
Myriad
DATA
Scripps
Caprion
SSS
Administrative Center
PIR
VBI
1 Project Catalog Summary View. Summarizes all
information currently available. www.proteomicsres
ource.org/Resources/Catalog.aspx
2 Master Protein Directory. Allows you to browse
and search the directory of proteins and reagents
identified by the NIAID Biodefense Proteomics
Research Centers. The directory integrates
information from the UniProt, iProClass and PIRSF
databases to link protein sequence and functional
annotation to experimental data.
5 Download Data. Experimental Data can be
downloaded in community formats (mzData) for
further analysis.
4 Protein Bank. Protein Bank contains
experimental data and protocols from Proteomics
Research Centers
3 Master Directory Links to Annotation. Links
proteins to functional family annotation in PIRSF
and other databases
Acknowledgements Supported by National
Institutes of Allergy and Infectious Disease/NIH
Contract HHSN266200400061C
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