LET THERE BE LIGHT The Canadian Light Source CLS

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LET THERE BE LIGHT!The Canadian Light Source (
CLS )

• G.M.Bancroft
• Chemistry Department
• University of Western Ontario
• London, Ontario
• Canadian Light Source
• University of Saskatchewan
• Saskatoon, Saskatchewan
• Royal Canadian Institute for the
  advancement of science, October 31,2004

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OUTLINE

• What is the light ? How is it produced?
  Beamlines, History.
• CLS facility to produce the light . Schedules and
  Funding.
• Research at CLS medical imaging,
  pharmaceuticals , materials science ,
  environmental, etc

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What is the LIGHT??

• The light contains visible light , but also
  infrared,
• ultraviolet , soft x-rays and hard x-rays
• 2. Over 30 extremely intense beams of this
  light are
• obtained from one facility such as the CLS.
• 3.The beams can be very small

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Electromagnetic Spectrum
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How is the Light Produced?
The Light ( IR , UV, x-rays ) is produced by
BENDING a very high energy beam of electrons in
a magnetic field. A number of these magnets
force the beam of electrons to go around
continuously a storage ring or a synchrotron
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Synchrotron Source
RF Cavity
Bending Magnets
Injector
Aladdin Synchrotron University of
Wisconsin Madison ,Wisconsin
vc
e-
Undulator
10s of meters
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Brightness
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Sample Microprobe Beamline Layout
ASI
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Medical Imaging in Europe
Original patient chair for diagnostic, cellular
scans, full-body treatments, at
ESRF in France
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Global
2nd Generation
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SR in Canada-the first 30 years

• 1) October,1972- First SR group Meeting at
  UWO (McGowan)
• 2) 1975- Proposal from UWO for National
  Laboratory for SR studies to NRC . NO!!
• 3) 1975 -First SR users- Crozier, Stanford
  Bancroft, U. Wisc.
• 4) 1980 -UWO and NRC set up CSRF in Madison
  three beamlines 1981,1988,1995. UWO still
  manages this.
• 5) 1990- formation of the Canadian
  Institute of Synchrotron Radiation . I was
  President from 1990-1999 .
• 6) 1995- 2 applications to NSERC for the
  CLS UWO and USask
• 7) 1997- funding of the Canada Foundation
  for Innovation
• 8) 1999 ( September) - ground breaking at U
  Sask
• 9) 2004 ( October 22 ) - Grand opening of
  CLS

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Planning Schedule
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Sample Microprobe Beamline Layout
ASI
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Medical Imaging in Europe
Original patient chair for diagnostic, cellular
scans, full-body treatments, at
ESRF in France
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Global
2nd Generation
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SR in Canada-the first 30 years

• 1) October,1972- First SR group Meeting at
  UWO (McGowan)
• 2) 1975- Proposal from UWO for National
  Laboratory for SR studies to NRC . NO!!
• 3) 1975 -First SR users- Crozier, Stanford
  Bancroft, U. Wisc.
• 4) 1980 -UWO and NRC set up CSRF in Madison
  three beamlines 1981,1988,1995. UWO still
  manages this.
• 5) 1990- formation of the Canadian
  Institute of Synchrotron Radiation . I was
  President from 1990-1999 .
• 6) 1995- 2 applications to NSERC for the
  CLS UWO and USask
• 7) 1997- funding of the Canada Foundation
  for Innovation
• 8) 1999 ( September) - ground breaking at U
  Sask
• 9) 2004 ( October 22 ) - Grand opening of
  CLS

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Planning Schedule
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Initial Capital Funding 140.9MTotal project
value of 173M
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The Construction Site
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Synchrotron Facility Components
2. Transfer Line Booster ring
1. E-gun
3. Storage ring
4. Beamline end station
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Synchrotron Hall, Main Floor
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The Synchrotron Floor , SGM beamline, March 2004
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SCIENCE AT THE CLS
(www.lightsource.ca/science )

• The CLS is committed to providing excellent SR
  capabilities in
• Materials science ( Mostly soft x-ray
  techniques - XPS , XAFS, XEOL, STXM, X-PEEM,
  XES, plus IR and some hard x-ray techniques
  below )
• Environmental Science ( Mostly hard x-ray
  techniques- XAFS , micro-XAFS/flourescence
  imaging , and diffraction plus IR , and the
  above soft x-ray techniques.
• 3. Life Sciences ( Medical Imaging
  ,Protein crystallography , IR , plus other soft
  and hard x-ray techniques )

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ESRF Medical Imaging
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Synchrotron Medical ImagingX-ray Techniques for
Live Mouse Alveoli
SPring-8
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Health Protein Crystallography
Some cancer growths can be controlled by designer
drugs
Synchrotron protein crystallography leads to
better understanding of drug protein
interactions M Vandonselaar, RA Hickie, JW
Quail, LTJ Delbaere, (1994) Nature Structure
Biology, Vol. 1. pp. 795-801
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Scar tissue formation in 65-day CMP hamster

K.M. Gough, et al . Analytical Biochemistry 316,
232 (2003).
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Beethovens HairForensic Applications

• Lock of hair taken day after death
• Non-destructive testing at APS
• Lead at 100 times typical levels
• No elevated mercury
• Confirms previous results from McCrone Associates
• Future imaging to reveal timeline of lead exposure

K. Kemner, D. Mancini, F. DeCarlo
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Antiwear Films ZDDP

• Zn Dialkyl dithiphosphate (R Alkyl or Aryl)
• Decomposes on metal surfaces in sliding contact
• ZDDP ? Polyphosphates Sulfides
• Anti-wear Anti-oxidant
• Reduces friction, wear corrosion
• Improving environmental additives of lubricants

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Nicholls, Kasrai, Bancroft, Norton , Tribolgy
Letters , 17, 245,(2004).
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Present Environmental SR Activity from CLS Users
(from CSC conference , August 12 / 03)

• 18 presentations mostly XAFS analyses of heavy
  metals in
• 1. Mine tailings 2. Minerals
  3. Meteorites
• Aquous solutions 5. Vegetable leaves
  6. Bacteria
• Fish livers 8. Human livers and
  hair 9. Worms
• 10. Trees 11. Coals and
  bitumens

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Biochemistry
Where is chromium Cr(VI) reduced to less
dangerous Cr(III) in plant roots?
Understand biochemistry associated within nuclei
of plant roots
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Microprobe Study of Mine Tailings
500 mm
As(-1) As(III)
As(V)
500 mm
11.88
11.86
11.90
Energy (keV)
Nickel Map
Arsenic Map
As(-1) As(III)
As(V)
11.86
11.88
11.90
Energy (keV)
Photon Energy 12 keV Spot size 5mm
Iron Map
Calcium Map
D.T. Jiang, J.N. Cutler, B.T. Moldocan et al .
Envir. Sci . Tech. 37 , 873 (2003)
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First Data from the CLS VLS - PGM beamline (Oct.
2004)