ANTI RETRO VIRAL THERAPY'

1
ANTI RETRO VIRAL THERAPY.

• AT DISTRICT LEVEL.
• DR.G.MANOHARAN.

2
WHEN ?

• COUNSELLING INDIVIDUAL FAMILY FINA
  NCIAL
• COST, DURATION,TOXIC PROFILE, NECESSITY TO CHANGE
  , IMPORTANCE OF MONITORING etc..

3
WHEN ?

• ALL SYMPTOMATIC PATIENTS.
• ASYMPTOMATIC PATIENTS VIRAL LOAD gt 55,000
  copies/ml CD4 cells lt 200 cells/cu.mm

4
WHAT DRUGS ?

• 2 NRTI 1 NNRTI
• 2 NRTI 1 PI
• ZIDOVUDINE, LAMIVUDINE, STAVUDINE
• NEVIRAPINE EFAVIRANZ
• PROTEASE INHIBITORS ( ANY)

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NO

• MONO THERAPY ( Except in PMTCT)
• DUAL THERAPY.

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INVESTIGATIONS.

• At the start of therapy. Viral Load
  (RT-PCR) CD4 cell count haematology,
  renal hepatic profile, Blood Sugar,Lipid
  Profile,HBsAg,HCV, Ultra sound abdomen, chest x
  ray etc..
• Repeat after 3 to 6 Months, again 6 months
  later, every year.

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WATCH FOR

• TOXIC EFFECT OF DRUGS
• ASSESS QUALITY OF LIFE.
• CONCENTRATE ON COMPLIANCE.
• OCCURRENCE OF OIs

8
THANK YOU.