How to Write Effective Meta-Analysis Research Papers - PowerPoint PPT Presentation

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How to Write Effective Meta-Analysis Research Papers

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When a study combines and statistically analyzed the finding of various studies, such a study is termed as meta-analysis study. The purpose of a meta-analysis study is to integrate the findings of various studies done on almost similar topics. – PowerPoint PPT presentation

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Title: How to Write Effective Meta-Analysis Research Papers


1
How to Write Effective Meta-Analysis Research
Papers
2
What is Meta-Analysis Research Study?
  • Various studies are done on similar or
    approximately similar topics. These studies are
    done at different time-period and in different
    regions. Each study has its analysis. When a
    study combines and statistically analyzed the
    finding of various studies, such a study is
    termed as meta-analysis study. The purpose of a
    meta-analysis study is to integrate the findings
    of various studies done on almost similar topics.
  • In most cases, the studies involved in a
    meta-analysis are randomized, controlled clinical
    trials. Meta-analysis is done to arrive at the
    precise conclusion about the risk factor for a
    disease, the effect of treatment on the disease,
    or the use of specific treatment against the
    disease. 

3
How to Write Effective Meta-Analysis Research
Papers?
  • Writing meta-analysis requires a lot of
    scrutinies and result in analysis. Following are
    the rules to be followed for writing the good and
    effective meta-analysis research paper
  • Research question and type of meta-analysis This
    is the first and one of the important steps for
    good meta-analysis.
  • Establish inclusion and exclusion
    criteria Before starting the meta-analysis, you
    should have a definite criterion in youre and to
    select and reject studies.
  • Detailed use of databases The author should be
    well-versed with various databases. You should
    perform a comprehensive, organized and systematic
    literature search to find the relevant studies. 

4
  • Use of various guidelines for meta-analysis Vario
    us guidelines for conducting a meta-analysis are
    available. These include Meta-analysis of
    Observational Studies in Epidemiology (MOOSE)
    statements, Quality of Reports of Meta-analyses
    of Randomized Controlled Trials (QUORUM), and
    Preferred Reporting Items for Systematic reviews
    and Meta-analyses (PRISMA).
  • Identifying statistical methods The author
    should identify the best statistical methods for
    meta-analysis that significantly reduces
    biasness.
  • Detailed data and data integrity Incorporate
    comprehensive data in your meta-analysis research
    paper. The quality of the study should also be
    good for accurate results.

5
  • Use of statistical software The author should
    have access to various meta-statistics software
    to carry out statistical analysis. Help from a
    professional statistician can be taken for
    carrying analysis.
  • Coding forms The author should define accurate
    coding forms to obtain relevant statistics. Good
    coding forms help in obtaining high-quality
    results.
  • Interpreting results and suggesting future
    scope Pay special attention to the discussion
    part of the research paper. Through discussion,
    the author discusses the results of a
    meta-analysis in comparison to current
    literature. Future scope of meta-analysis helps
    to initiate new studies in the forward direction.

6
What is the Need of Meta-Analysis Study?
  • Meta-analysis finds its importance in different
    aspects of the research process. These include
  • To simplify the complex data Meta-analysis is
    done to simplify the complex data. Data from
    various studies are taken and analyzed
    statistically.  Further, meta-analysis provides a
    more complex data analysis related to outcome,
    safety, and efficacy.
  • Publications Meta-analysis is required during
    the publication of the primary study in journals.
    Meta-analysis plays an important role in
    recognizing the outcomes available from the prior
    studies which are related to the research topic
    in context. Through meta-analysis, the researcher
    submits the prior data in the introduction of the
    primary research study.

7
  • Studies with conflicting results Studies on a
    similar research topic may have conflicting
    results. For instance, some studies advocate the
    use of calcium in pre-eclampsia while other
    studies indicate that there is no effect of
    calcium supplementation on pre-eclampsia.
  • Grant applications Fund or grant is required to
    perform a new study. For preparing the proposal
    for the fund, meta-analysis is done to
    consolidate the available data and to determine
    the need for a new study.
  • Performing new studies Meta-analysis analyzes
    all the relevant studies available on a specific
    research topic. This helps in determining the
    specific requirement for conducting a new study.
    Meta-analysis provides insight about which
    outcomes are already measured in prior data and
    which still requires an answer.

8
What are the Characteristics of Meta-Analysis
Research Study?
  • Following are the characteristics of a
    meta-analysis research study
  • Statistical method Meta-analysis is done to
    establish statistical significance among the
    studies already done in a specific area of
    research with conflicting results. It helps in
    increasing the validity of differences in
    different studies. Meta-analysis requires
    detailed statistical skills.
  • Use of prior data Meta-analysis does not
    initiate altogether new research i.e. it is not
    primary research. It uses the data from the
    studies that had already taken place.

9
  • Evidence evaluation Meta-analysis is done to
    determine the strength of evidence present in the
    prior art in context to a specific area of
    research. It also helps in determining the need
    for new primary research.
  • Increased sample size Many individual studies
    have a common problem of small sample size. This
    problem is solved through meta-analysis. A
    meta-analysis combines the samples of different
    studies to reach an accurate, valid and precise
    conclusion.
  • Different subsets Meta-analysis evaluates the
    cause-effect relationship in different studies
    i.e. different subsets of the subjects. The
    result of meta-analysis can be extrapolated to a
    larger population.

10
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