Clinical Studies In Ashwagandha

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Latest Clinical Studies In Ashwagandha
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Ashwagandha

• Ashwagandha, popularly known as Indian Ginseng,
  is one of the most well-known and widely used
  Ayurvedic herbs. Helpful in various functions in
  the body from sleep, energy, and stress relief to
  rejuvenation, muscle strength, and joint health,
  the herb is popular for a valid reason.
• Due to this versatility in human health, the herb
  is gaining more and more popularity amongst the
  herbalists from all backgrounds naturopaths,
  Chinese medicine, and Western herbalists,
  especially in America.

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Heres a synopsis of the 7 latest clinical
studies on Ashwagandha and what they revealed
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1) Effect on physical strength

• Researchers at Lindenwood Universitys Exercise
  and Performance Nutrition Laboratory1 investigat
  ed the effects of Sensoril, a patented, aqueous
  extract of the roots and leaves of Ashwagandha on
  men.
• This 12-week study revealed significant
  improvement in average squat power and peak bench
  press power in men who ingested 500 mg of this
  aqueous extract daily.

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2) Improvement in memory and cognitive function

• Efficacy and safety of Ashwagandha root extract
  in improving memory and cognitive functions was
  studied in Chicago in 2017.2
• Thus, Ashwagandha root proved to be effective in
  enhancing both immediate and general memory in
  people with MCI as well as improving executive
  function, attention, and information processing
  speed.

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3) Effect on immune function

• A study was conducted to investigate the
  immunologic effects of Ashwagandha on four types
  of immune cells in human beings.
• Researchers observed a significant increase in
  the expression of CD4 on CD3 T cells after 96
  hours. CD56 NK cells were also activated after
  96 hours as evidenced by expression of the CD69
  receptor. The results indicated a major change in
  immune cell activation in the participants
  sample.3

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4) Stress and Anxiety Relief

• An 8-week study was conducted to evaluate the
  safety and efficacy of a standardised root
  extract of Ashwagandha through a double-blind,
  randomised, placebo-controlled trial. 52 subjects
  suffering from chronic stress received either
  Ashwagandha (300 mg) or placebo twice daily.
• Each participant was assessed at the start, at 4
  weeks, and 8 weeks. Ashwagandha demonstrated
  significant improvements in primary and secondary
  measures and was found to be safe and tolerable.
  This study suggests that Ashwagandha root extract
  can be used for body weight management in adults
  under chronic stress.4

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5) Focus and Concentration

• In a double-blind, placebo-controlled study, 20
  healthy males were given 500 mg of Ashwagandha
  root extract for fourteen days. The participants
  showed significant cognitive improvement in
  reaction-time tests, discrimination tests, and in
  card sorting tests, among many others.
• These results prove Ashwagandhas ability to
  support attention, memory, focus, concentration,
  and responsiveness and coordination between the
  mind and motor functions. 5

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6) Rejuvenation

• A trial was conducted with healthy male
  volunteers aged fifty to sixty-nine. All the
  volunteers were given purified Ashwagandha powder
  in the dose of 3 grams per day for one year.
  After a year, these males showed an increase in
  blood counts, improved posture, and increased
  hair melanin (pigmentation of the hair). 6
• In another study, healthy children were given 2
  grams of powdered Ashwagandha in milk and they
  experienced improvements in blood counts, body
  weight, and hand strength.

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7) Sleep and Emotional Health

• A survey study was conducted with 218 healthy
  participants who were given 1200 mg of the
  Ashwagandha herb two times a day for one month.
  The participants noted 66.9 improvement in their
  sleep quality. This can be attributed to the
  decreased stress levels in the participants. 7
• The herb also demonstrated a positive effect of
  enhancing the participants emotional health by
  42. The positive effects on emotional health
  translated to the participants social life and
  social activities being improved by nearly 45.8.
  

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References 1 Ziegenfuss TN, Kedia AW, Sandrock
JE3, Raub BJ, Kerksick CM, Lopez HL.  2018 Nov
2010 https//www.ncbi.nlm.nih.gov/pubmed/3046332
4 2 Choudhary, D., Bhattacharyya, S., Bose,
S. (2017). Journal of Dietary Supplements, 1-14.
Chicago 3 Mikolai J, Erlandsen
A https//www.ncbi.nlm.nih.gov/pubmed/19388865, Mu
rison A, Brown KA, Gregory WL, Raman-Caplan
P, Zwickey HL J Altern Complement Med. 2009
Apr15 4 D Choudhary, et al. Body Weight
Management in Adults Under Chronic Stress Through
Treatment with Ashwagandha Root Extract A
Double-Blind, Randomized, Placebo-Controlled
Trial. J Evid Based Complementary Altern Med.
April 6, 2016. 5 U Pingali, et al. Effect of
standardized aqueous extract of Withania
somnifera on tests of cognitive and
psychomotor performance in healthy human
subjects. Pharmacognosy Res. 6, no 1 (January
2014)12-8. 6  Lakshmi-Chandra Mishra, Betsy
Singh, and Simon Dagenais. Scientific Basis for
the Therapeutic Use of Withania somnifera
(Ashwagandha) A Review. Alternative Medicine
Review. 5, no 4 (2000)334-346 7 Sebastian
Pole, Ayurvedic Medicine The Principles of
Traditional Practice (London Churchill
Livingston, 2006), pp. 133-134.
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