Yeast Expression System

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Yeast Expression System
Creative BioMart
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As a well-defined and economical eukaryotic
expression system for both secretory and
intracellular expression, yeast protein
expression system is perfectly suitable for
large-scale manufacture of recombinant proteins.
Creative BioMart has developed yeast expression
vectors that are optimized for the efficient
production of heterologous proteins. We have also
a few strong signal sequences to ensure the
highest secretion level.
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All of below advantages make yeast expression
system an ideal host for producing large
quantities of properly folded proteins in a short
period of time High yield High
productivity Genetics can be easily
manipulated Chemically defined media Complex
post-translational modifications Stable
production strains Durability Ease of scaling
up Low protein production cost
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At Creative BioMart, our expertise in protein
expression extends to both Saccharomyces.
cerevisiae and Pichia. pastoris expression
systems. Expression of recombinant proteins in S.
cerevisiae can be done using three types of
vectors
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Yeast integrating plasmid Replicating single copy
plasmid For integration into genomic locus
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Yeast centromeric plasmid Replicating single copy
plasmid For complementation studies
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Yeast episomal plasmid Replicating multi-copy
plasmid For recombinant protein production,
multicopy suppression studies, etc.
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Saccharomyces. cerevisiae Full genomic sequence
known Well developed genetic methods About 6000
genes A model to other eukaryotes GRAS No
toxins Ability to secrete proteins Capacity for
post-translational modifications
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Besides, methylotrophic Pichia.pastoris is a
distinguished system for its growth to very high
cell densities, for the available strong and
tightly regulated promoters, and for the options
to produce gram amounts of recombinant protein
per liter of culture. If you're looking for
protein production via fed-batch pichia
processes, we have the experienced and
credentialed staff to move your project forward.
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Thanks for watching! Contact Creative
BioMart Address 45-1 Ramsey Road Shirley, NY
11967, USA Email contact_at_creative-biomart.com W
ebsite http//www.creativebiomart.net