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Liver Cancer Treatment In India

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Liver Cancer or Hepatic Tumour is a cancer of Liver. There are several different types of tumours that can develop in the liver as liver is made up of various cell types. These growths can be benign or malignant. Cancerous tumours can start in liver and spread to other areas of your body, through your bloodstream or your lymphatic system. This spread of cancer is called metastasis. Tumours may also spread from other parts of your body, such as from your bowel, breast or lungs, to your liver. – PowerPoint PPT presentation

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Title: Liver Cancer Treatment In India


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LIVER CANCER Liver Cancer or Hepatic Tumour is a
cancer of Liver. There are several different
types of tumours that can develop in the liver as
liver is made up of various cell types.  These
growths can be benign or malignant. Cancerous
tumours can start in liver and spread to other
areas of your body, through your bloodstream or
your lymphatic system. This spread of cancer is
called metastasis. Tumours may also spread from
other parts of your body, such as from your
bowel, breast or lungs, to your liver.
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  • Symptoms of Liver Cancer
  • Most people do not have signs and symptoms in the
    early stages of primary liver cancer. When
    symptoms do appear, they may include
  • Losing weight without trying
  • Loss of appetite
  • Upper abdominal pain
  • Nausea and vomiting
  • General weakness and fatigue
  • An enlarged liver
  • Abdominal swelling
  • Yellow discoloration of your skin and the whites
    of your eyes (jaundice)
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Types of Liver Cancer Two broad categories of
liver cancer 1) Primary 2)
Secondary Primary Liver Cancer Primary liver
cancer starts in the cells, bile ducts, blood
vessels or connective tissue of the liver . There
are different types of primary liver cancer that
include Hepatoma  This is the most common
type. It is sometimes called hepatocellular
carcinoma (HCC). This type of cancer originates
from a liver cell (hepatocyte) which becomes
cancerous. The bulk of the liver is made up from
hepatocytes. A hepatoma most commonly develops as
a complication of liver diseases such as
cirrhosis or types of hepatitis (liver
inflammation). Fibrolamellar  This hepatoma is
a rare sub-type of hepatoma. It typically
develops in a liver that was previously
healthy. Cholangiocarcinoma  This is uncommon.
It develops from cells which line the bile
duct. Hepatoblastoma  This is a very rare
cancer that occurs in some young
children. Angiosarcoma  This is very rare. It
develops from cells of blood vessels within the
liver.
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Secondary Liver Cancer Secondary liver cancer is
a cancer that first develops elsewhere in the
body and then spreads (metastasizes) to the
liver. It is sometimes called metastatic
cancer. When a cancer forms in a part of the
body, a few cancer cells may break off and find
their way into the bloodstream. Because your
liver filters your blood, any cancer cells in the
bloodstream have a high chance of settling in the
liver to form a cancer nodule (metastasis). Peopl
e who are most at risk of secondary liver cancer
are those with cancers of the large bowel
(colon), pancreas, stomach, lung or breast. It is
important to know where the cancer started as
this will determine the type of cells which are
causing the cancer and affect which treatment is
best suited for you. Secondary cancer diagnosed
in the liver may be a sign of cancer in other
organs. Sometimes, secondary cancer is found in
the liver and yet, even with thorough medical
tests, its not possible to find out where the
cancer started. This is sometimes known as cancer
of unknown primary.
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Staging of Liver Cancer There are a number of
different systems that can be used to stage liver
cancer. Many liver cancer specialists use
combination-staging systems that include features
of both the cancer and liver function to stage a
persons condition. One combination system for
staging liver cancer is known as the Barcelona
Clinic Liver Cancer (BCLC) staging system that
consists of the following five stages. Stage 0
- The tumour is less than 2cm (20mm) in diameter
and the person is very well and has normal liver
function. Stage A - A single tumour has grown
but is less than 5cm (50mm) in diameter, or there
are three or fewer smaller tumours that are less
than 3cm (30mm) in diameter and the person is
very well with normal liver function. Stage B
- There are multiple tumours in the liver, but
the person is well and their liver function is
unaffected. Stage C - Any of the above
circumstances, but the person is not so well and
their liver function is not so good or where the
cancer has started to spread into the main blood
vessel of the liver, into nearby lymph nodes or
into other parts of the body. Stage D  Where
the liver has lost most of its functioning
abilities and the person begins to have symptoms
of end-stage liver disease, such as a build-up of
fluid inside their abdomen.
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Diagnosis of Liver Cancer Physical exam -- The
doctor feels the abdomen to check the liver,
spleen, and nearby organs for any lumps or
changes in their shape or size. The doctor also
checks for ascites, an abnormal buildup of fluid
in the abdomen. The doctor may examine the skin
and eyes for signs of jaundice. Blood tests --
Many blood tests may be used to check for liver
problems. One blood test detects
alpha-fetoprotein (AFP). High AFP levels could be
a sign of liver cancer. Other blood tests can
show how well the liver is working. CT scan --
An x-ray machine linked to a computer takes a
series of detailed pictures of the liver and
other organs and blood vessels in the abdomen.
The patient may receive an injection of a special
dye so the liver shows up clearly in the
pictures. From the CT scan, the doctor may see
tumors in the liver or elsewhere in the
abdomen. MRI -- A powerful magnet linked to a
computer is used to make detailed pictures of
areas inside the body. These pictures are viewed
on a monitor and can also be printed.
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Ultrasound test -- The ultrasound device uses
sound waves that cannot be heard by humans. The
sound waves produce a pattern of echoes as they
bounce off internal organs. The echoes create a
picture (sonogram) of the liver and other organs
in the abdomen. Tumors may produce echoes that
are different from the echoes made by healthy
tissues. Angiogram -- For an angiogram, the
patient may be in the hospital and may have
anesthesia. The doctor injects dye into an artery
so that the blood vessels in the liver show up on
an x-ray. The angiogram can reveal a tumor in the
liver. Biopsy -- In some cases, the doctor may
remove a sample of tissue. A pathologist uses a
microscope to look for cancer cells in the
tissue. The doctor may obtain tissue in several
ways. One way is by inserting a thin needle into
the liver to remove a small amount of tissue.
This is called fine-needle aspiration. The doctor
may use CT or ultrasound to guide the needle.
Sometimes the doctor obtains a sample of tissue
with a thick needle (core biopsy) or by inserting
a thin, lighted tube (laparoscope) into a small
incision in the abdomen. Another way is to remove
tissue during an operation.
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Liver Cancer Treatment at Top Cancer Hospitals in
India   The treatment options are dictated by the
stage of Liver Cancer and the overall condition
of the patient. The treatment to be given depends
mainly on the size, number, and site of tumors in
the liver. Before planning the appropriate
treatment the functioning of the Liver is checked
as also the spread of the cancer within and
outside the liver is to be tested. The Various
treatment options available are as
follows Surgery  Surgery is the removal of the
tumor and surrounding tissue during an operation.
It is likely to be the most successful
disease-directed treatment, particularly for
patients with small tumors (smaller than 5 cm). A
surgical oncologist is a doctor who specializes
in treating cancer using surgery.
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Hepatectomy  When a portion of the liver is
removed, the surgery is called a Hepatectomy. A
Hepatectomy can be done only if the cancer is in
one part of the liver, and the liver is working
well. The remaining section of liver takes over
the functions of the entire liver and may regrow
to its normal size within a few weeks. Liver
Transplantation Liver transplant may be the best
option for some people with small liver cancers.
At this time, liver transplants are reserved for
those with small tumors (either 1 tumor smaller
than 5 cm across or 2 to 3 tumors no larger than
3 cm) that have not invaded nearby blood vessels.
In most cases, transplant is used for tumors that
cannot be totally removed, either because of the
location of the tumors or because the liver is
too diseased for the patient to withstand
removing part of it. Chemoembolization This is
a type of chemotherapy treatment in which drugs
are injected into the hepatic artery and then the
flow of blood through the artery is blocked for a
short time so the chemotherapy stays in the tumor
longer. Blocking the blood supply to the tumor
also kills cancer cells.
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Radiation Therapy  Radiation therapy is the use
of high-energy x-rays or other particles to kill
cancer cells. A doctor who specializes in giving
radiation therapy to treat cancer is called a
radiation oncologist. A radiation therapy regimen
(schedule) usually consists of a specific number
of treatments given over a set period of time.
External-beam radiation therapy is radiation
given from a machine outside the body.
External-beam radiation therapy is not often used
for HCC. Targeted Therapy  Targeted therapy is
a treatment that targets the cancers specific
genes, proteins, or the tissue environment that
contributes to cancer growth and survival. This
type of treatment blocks the growth and spread of
cancer cells while limiting damage to normal
cells. Recent studies show that not all tumors
have the same targets. To find the most effective
treatment, your doctor may run tests to identify
the genes, proteins, and other factors in your
tumor.
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Most Advance Non surgical Treatments for Liver
Cancer in India Chemoembolization  Before
Insertion of the tiny particles that block the
blood flow an anticancer drug is injected into
the artery. The drug stays in the liver for
longer without blood flow, and thus the impact is
more. Radiofrequency Ablation  For inoperable
liver tumors, radiofrequency ablation (RFA)
offers a nonsurgical, localized treatment that
kills the tumor cells with heat, while sparing
the healthy liver tissue. Thus, this treatment is
much easier on the patient than systemic
therapy. Cryosurgery  It is a treatment that
uses an instrument to freeze and destroy abnormal
tissue, such as cancerous cells. This type of
treatment is also called Cryotherapy. The doctor
may use ultrasound to guide the instrument.
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Percutaneous Ethanol Injection  Percutaneous
ethanol injection is a cancer treatment in which
a small needle is used to inject ethanol
(alcohol) directly into a tumor to kill cancer
cells. The procedure may be done once or twice a
week. Usually local anesthesia is used, but if
the patient has many tumors in the liver, general
anesthesia may be needed. Hyperthermia Therapy
 Hyperthermia therapy is a type of treatment in
which body tissue is exposed to high temperatures
to damage and kill cancer cells or to make cancer
cells more sensitive to the effects of radiation
and certain anticancer drugs. Because some cancer
cells are more sensitive to heat than normal
cells are, the cancer cells die and the tumor
shrinks. Biologic Therapy  Biologic therapy is
a treatment that uses the patients immune system
to fight cancer. Substances made by the body or
made in a laboratory are used to boost, direct,
or restore the bodys natural defenses against
cancer. This type of cancer treatment is also
called biotherapy or immunotherapy. 
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FAQ - Liver Cancer  Treatment India How is liver
cancer diagnosed? If you think you have liver
cancer, you should have a medical exam. Many
tests may be needed to confirm liver cancer. The
steps to diagnosing liver cancer are a medical
history, physical exam, imaging tests, and a
liver biopsy.  Whats new in liver cancer
research? Heres an overview of some new
prevention and treatment methods being
studied Ways to prevent hepatitis infections
that cause liver cancer . Drugs that treat
chronic hepatitis. Scientists think hepatitis
vaccinations may help prevent many cases of liver
cancer.. New forms of targeted therapy, including
drugs that can be taken in higher doses How to
find the Best liver Cancer Treatment and Surgery
in India? As there are many top class surgeons in
India, finding the best can be tricky. Send us
your medical report and we will choose from among
the best surgeons most suitable for your
condition. Why people Choose India for liver
Cancer Treatment and Surgery? Liver cancer
hospitals in India specialize in advanced that
fight cancer while supporting your quality of
life, both during and after treatment. 
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