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My own scientific career was

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I went from animals to cells, from cells to bacteria, from bacteria to molecules, ... alkane alkene 2e- (to FAD as 2 H.) alcohol ketone 2e- (to NADH as H:) H ... – PowerPoint PPT presentation

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Title: My own scientific career was


1
My own scientific career was a descent from
higher to lower dimensions, led by a desire to
understand life. I went from animals to cells,
from cells to bacteria, from bacteria to
molecules, from molecules to electrons. The story
had its irony, for molecules and electrons have
no life at all. On my way life ran out between
my fingers.
Albert Szent-Gyorgi, The Living State, 1972
(discoverer of vitamin C and the actin-myosin
motor)
2
alkane ? alkene 2e- (to FAD as 2 H.) alcohol ?
ketone 2e- (to NADH as H) H
3
Cell for measurement of e- affinity
if x has higher e- affinity than H
if x has lower e- affinity than H
e-
e-
(voltage)
(-voltage)
H/H2
Xox/Xred
4
high e- affinity
5
low e- affinity
6
Pryidine nucleotides mobile, water-soluble e-
carriers (cosubstrates)
7
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8
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9
flavin nucleotides protein-bound e- carriers
(prosthetic groups)
10
(No Transcript)
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