Title: Anatomical approaches
1Anatomical approaches
- Comparative embryology
- Evolutionary embryology
- Teratology
- Mathematical modeling
2Evolutionary embryology
Jaw apparatus
3Medical embryology
Birth defects Example - KIT gene
mutations Animal models
4Medical embryology
Teratology Example Thalidomide
5Maths in Developmental Biology???!!!
Mathematics of growth Example increase of
size between larval molts Isometric
Spiral growth Example Rams horn and
nautiluss shell
6Mathematics of growth
Allometric growth
log y log b (a/c)log x a and c are growth
rates of two different body parts x initial
body size b is y when x 1
7Mathematics of growth
Allometric growth
log y log b (a/c)log x
Uca pugnax
8Mathmatics of patterning Turings
Reaction-Diffusion model
9Mathmatics of patterning Turings
Reaction-Diffusion model
10Life cycle
The view taken here is that the life cycle is
the central unit in biology. Evolution then
becomes the alteration of life cycles through
time, genetics the inheritance mechanisms between
cycles, and development all the changes in
structure that take place during one life
cycle. - J.T. BONNER (1965)
11Life cycle
12Life cycle of frog
13Life cycle of frog
14Life cycle of frog
15Metamorphosis of frog