talk in taiwan, 27/8/2001

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Bioinformatics _at_ KRDL
Limsoon Wong Kent Ridge Digital Labs
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What are the Themes of Bioinformatics?
Bioinformatics Data Mgmt Knowledge
Discovery Data Mgmt Integration
Transformation Cleansing Knowledge Discovery
Statistics Algorithms Databases
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Protein Interaction Extraction
What are the protein-protein interaction
pathways from the latest reported discoveries?
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Protein Interaction Extraction Results

• Rule-based system for processing free texts in
  scientific abstracts
• Specialized in
• extracting protein names
• extracting protein-protein interactions

Jak1
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Transcription Start Prediction
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Transcription Start Prediction Results
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Medical Record Analysis

• Looking for patterns that are
• valid
• novel
• useful
• understandable

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Medical Record Analysis Results

• DeEPs, the emerging pattern method
• Beats C4.5, CBA, LB, NB, TAN in 21 out of 32 UCI
  benchmarks
• Works for gene expressions
• ALL vs AML
• DeEPS (1 gene) - 0/38 3/34
• Slonim (50 genes) - 2/38 5/34
• Colon
• DeEPS (35 genes) - 4/62
• Alon (1000 genes) - 6/62

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Thank You Have a Nice Day
For more info http//sdmc.krdl.org.sg/bic http//
sdmc.krdl.org.sg/limsoon/talks/wls-genemaster.ppt