Integrating Nanostructures with Biological Structures

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Integrating Nanostructures with Biological
Structures Investigators M. Stroscio, ECE and
BioE M. Dutta, ECE Prime Grant Support ARO,
NSF, AFOSR, SRC, DARPA, DHS
Problem Statement and Motivation

• Coupling manmade nanostructures with biological
  structures to monitor and control biological
  processes.
• For underlying concepts see Biological
  Nanostructures and Applications of Nanostructures
  in Biology Electrical, Mechanical, Optical
  Properties, edited by Michael A. Stroscio and
  Mitra Dutta (Kluwer, New York, 2004).

Technical Approach
Key Achievements and Future Goals

• Synthesis of nanostructures
• Binding nanostructures to manmade structures
• Modeling electrical, optical and mechanical
• properties of nanostructures
• Experimental characterization of intergated
  manmade
• nanostructure-biological structures

• Numerous manmade nanostructures have been
  functionalized with biomolecules
• Nanostructure-biomolecule complexes have been
  used to study a variety of biological structures
  including cells
• Interactions between nanostructures with
  biomolecules and with biological environments
  have been modeled for a wide variety of systems
• Ultimate goal is controlling biological systems
  at the nanoscale