The Plasma Membrane a Phospholipid Bilayer

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The Plasma Membrane a Phospholipid Bilayer
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Components of Plasma Membrane
Lipids
Proteins
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1) Phospholipids
1) Peripheral (Associated)
2) Cholesterol
2) Integral (Membrane Spanning)
3) Glycolipds
3) Glycoproteins
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Roles of the Plasma Membrane
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Protein Transporters
2) Carriers
1) Channels
a) open
b) gated
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Cell Transport Mechanisms
Passive
Active
1) Diffusion
1) Primary (Direct)
2) Facilitated Diffusion
2) Secondary (Indirect)
3) Vesicular
3) Filtration
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Diffusion
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Passive Transport
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Primary Active Transport The Na/K Pump
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The Na/K Pump
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Secondary Active (Indirect)
e.g., Na- glucose Symport
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Endocytosis and Exocytosis
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Transcytosis e.g., inside Vesicle.
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Distribution of Water and Solutes in the Body
Compartments
Inside cells

• About 60-70 of body weight is water

• 67 is intracellular

• 33 is extracellular
• 8 plasma
• 25 interstitial

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Transcapillary Fluid Dynamics
?HP
(plasma in capillary)
?HP
venous end
arterial end
?? COP
?? COP
Filtration
Reabsorption
?? COP
?HP
(interstitium)
(ICF)
fluid movement
Cells
HP Hydrostatic Pressure (force of a fluid on
walls of its container)
COP Colloid Osmotic Pressure (force generated
by proteins in solution)
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• Uses ATP to move products
• Up a concentration gradient

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