A Shift in Perspective

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Strategic Intent

• Upsher-Smith is an innovative developer,
  manufacturer, and marketer of products promoted
  to pharmacists, target physician groups and other
  healthcare professionals in the US

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Privately heldcustomer focused

• Privately held company established in 1919 by
  F.A. Upsher-Smith
• Ken Evenstad, Chairman CEO
• Pharmacist and entrepreneur
• Ernst Youngs Entrepreneur of the Year
• Acquired Upsher-Smith in 1969
• Mark Evenstad, Vice Chairman President

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Three locations
one vision
Manufacturing Denver, CO
Corporate HQ Maple Grove, MN
Manufacturing Minneapolis, MN
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Established relationships across the industry

• NCPA Corporate Sponsor
• Member of NASPA
• Drug Topics
• Klor-Con listed in top 200 Drugs 11 years
  running
• HDMA Diana Award
• Three time award winner
• American Podiatric Medical Association
• First pharmaceutical company to receive
  Presidents Award
• Cardinal Health
• Consistent Quality Service Award recipient
• AmeriSource/Bergen
• Branded Supplier of the Year Award
• McKesson
• Branded Supplier of the Year Award

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Corporate Compliance and Quality Control

• Corporate Compliance
• Commitment to the highest ethical standards in
  the conduct of our business
• Long track record of successful regulatory
  inspections
• Quality Control
• Strong emphasis on quality and excellent customer
  service to ensure an uninterrupted product stream
• Comprehensive capabilities in all areas of
  analytical chemistry

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Sales

• Unique, effective integrated selling model
• Field Sales and Territory Sales Teams positioned
  to reach targeted physician specialties
• Retail Accounts Sales Team focused on building
  strong relationships within the Independent
  pharmacy market
• Trade Accounts
• Established relationships across all classes of
  trade
• Track record of rapid and extensive distribution
• Managed Care
• Experienced team
• Established relationships

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Early history Success in branded generics and
OTCs

• Cardiology
• Klor-Con
• Pacerone
• Jantoven
• Slo-Niacin
• Dermatology
• Amlactin
• AmlactinXL
• Clenia

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Womens health franchise

• Fortical calcitonin-salmon (rDNA origin) Nasal
  Spray
• Indicated for osteoporosis
• 505(b)(2) regulatory approval pathway
• Vandazole (metronidazole vaginal gel, 0.75)
• Indicated for bacterial vaginosis
• Non AB-rated alternative
• Divigel (estradiol gel, 0.01)
• Lowest approved 17-? estradiol dose
• Indicated for hot flashes associated with
  menopause
• PreNexa (pre-natal vitamin)
• Plant-based DHA
• Single poly-gel capsule, once daily dosing

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Future strategic focus within CNS

• Vision
• To become a leader in providing therapies that
  empower people suffering from central nervous
  system (CNS) diseases to lead healthy, productive
  lives
• Focus
• Innovative, NDA products within key therapeutic
  categories
• Epilepsy
• Parkinsons disease
• Strategy
• Combine internal development capabilities with
  aggressive in-licensing strategy

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