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Definitions

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Title: Definitions


1
Definitions
  • Macule color change, flat and smooth (large or
    small)
  • Pustule small circumscribed elevation of skin
    filled w/ cloudy white or yellow or green
    material
  • Fissure linear cleft through the epidermis-
    rarely into dermis
  • Cysts space occuping lesion, very sharply
    circumscribed, movable and copressible- sac
    containing liquid or semi-solid materials
  • Nodule larger than a papule in all three
    dimesions
  • Agagen hair cycle growth phase lasts 3-4 years
  • Vesicle fluid-filled lesion (clear) upto 0.5 cm
  • Abrasion superficial skin loss not penetrating
    the dermo-epidermal juncture
  • Urticaria evanescent, often pruritic, irregular
    shaped lesions w/in 1hr of eating seafood

2
Burns
  • 4th degreeDestroys full thickness of skin and
    underlying structures
  • 3rd degree split thickness skin graft- best long
    term healing
  • 2nd degree epidermis and various layers of the
    dermis

3
Escharotomy
  • No distal pulse
  • Circumfrential burn full thickness
  • Is a longitudinal incision to prevent blood flow
    disruption

4
Wound healing
  • 1st phase Inflammatory phase
  • Full- thickness wounds heal form edges
  • Maturation phase no net colloagen productions ,
    cross-linking occurs, flat more supple scar
  • Inflammatory phase no collagen, macrophages,
    PMNs present
  • Clean wound less than 100,000 organisms/gram of
    tissue
  • Proliferative phase raised, red scar, high
    collogen production
  • Prevention of infection soft tissue adequated
    debridement
  • Chemical spills must decontaminate first
  • Edema beneath burn skin ivntravascular volume
    loss death
  • Strength dermis-fascia
  • Prophylactic antibiotics insertion of vascular
    prosthesis
  • Short operation time low wound infections rate

5
Malignant fibrous histiocytoma
  • Histo atypical spindle cells storiform pattern
    bizarre cells

6
Superficial spreading melanoma
  • Pigmented lesion grows rapidly and starts
    vertically
  • 170 lifetime chance of getting
  • ABCD
  • Asymmetry of border
  • Border (scalloped)
  • Color (red, white, blue)
  • Diameter (6mm)

7
Breslow classification
  • 1.51 to 3.99mm deep regional metastasis
    incidence of 51

8
Basal cell carcinoma
  • Pearly, papule blood vessels over surface
  • Histo nest of basaloid cellsw/ peripheral
    palisading
  • Rarely metastasize
  • Rodent ulcer nodular basal cell carcinoma
  • Radiation non surgical candidate, and advanced
    lesions
  • MCC type nodular
  • MC skin cancer
  • Skin growing pearly papule / nodule, rolled
    raised border with central depression
  • () telangiectasia
  • Bleed if scratch
  • Lesion brown / black
  • DDx SCC v . BCC with biopsy
  • Tx imiquimod (aldara)

9
Malignant melanoma
  • Prognosis level and depth
  • Found in skin and conjunctiva
  • Dull red, central dork kerotoic plug, firm

10
Squamous cell carcinoma
  • Marjolins ulcer chronic unstable burn scars
  • 2 MC
  • Skin mucosal keratocytes
  • Chronic sun exposure
  • ORAL SCC
  • Lower lip,
  • Dome shaped crust, firm red nodule
  • Watch for metastase

11
Vitiligo
  • Disfiguring disease of unknown origin
    destruction of melanocytes
  • Woods light help diagnosis

12
Senile purpura
  • Purple patches, no blancheing
  • Corticosteroid use

13
Granuloma annulare
  • Dorsum of hand
  • Changed from discrete nodule to lesion w/
    circumferentially raised border, same color as
    adjacent skin antifungal does not work

14
Seborrheic keratosis
  • Uniform brown lesion
  • stuck on appearance
  • Sign of Leser-trelat

15
Senile (actinic) Keratosis
  • Premalignant lesion
  • Histo hyperkeratosis, acanthois, celluar atypia-
    lower dermis
  • Basophilic degeneration lymphocytic infiltration-
    upper dermis
  • Finely scaly, read to tan, irregular surface
  • 5 fluoro-uracil
  • Tx chemical peels
  • Progress to SCC (earliest stage)
  • Burn itch sting
  • Tx imiquimod (aldara)

16
dermatomyositis
  • Gottrons sign (papules over knuckles)
  • Heliotrope eruptions and upper eyelid edema
  • Poikiloderma
  • Pt. has difficulty combing hair, climbing stairs,
    getting up from chair

17
Seborrheic Dermatitis
  • Greasy yellow loose scaly
  • Face scalp nasal, labial, eyebrows, glabella,
    under arms, butt, groin
  • Tx
  • Ketoconazole
  • Green Tea Shampoos
  • Scale removal
  • Lopox gel / cream
  • Seborrheic Blepharitis
  • On eyelids

18
Lichen Planus
  • Saw-tooth patter of epithelium, liquefaction,
    band of mononuclear cells
  • Flexor aspects of wrists and forearms pruritic
    flat-topped, polygonal violaceous paules
  • () Auspitzs sign
  • Puruitic
  • Oral lesions painful
  • Rx hydrochlorothiazide
  • 5 Ps
  • Pruritis
  • Planar (flat topped)
  • Polyangular
  • Papule
  • Pterygium (triangle deformity of nails)
  • SSx

19
Pityriasis Rosea
  • Herald atch
  • Collarette of scale with in border not on
    outside

20
Bullous pemphigoid
  • Subepidermal non-acantholytic blister
  • Immunofluorescence linear IgG basement membrane
  • large tense bullae erythematous bse or normal
    skin older pts.
  • Benign no scar
  • Around umbilicus
  • Itch and burn
  • (-) Nikolsky sign
  • DOC predenisone (ID)

21
Pemphigus vulgaris
  • Tx systemic steroids and steroid-sparing meds
  • Intraeptithelial blister
  • Immunofluorescence intercellular IgG and
    complement
  • () nikolskys sign

22
Mongolian spot
  • Dark blueblack pigmented macularpathces
  • Childern slate colored, resolve spontaeously
  • Location butt and lower trunk

23
Psoriasis
  • Sharply defined silver-white plaques
  • MC elbows / knees
  • Histo acanthosis and elongations of the rete
    ridges, parakeratosis
  • Munro abscesses
  • Tx etretinate (tegison) - SQ
  • Tx PUVA (psoralens-vua radiation)- moa
    formation of DNA adduct decreased DNA
    replication
  • Tx Goeckermann Regimen
  • 90 effective for 9 months
  • UVB old tar
  • Tx Ingram regime
  • Goeckermann Regimen with anthralen instead of tar
  • Tx ethotrexate infiximab (Remicade) IV
    infusion Amevive (alafacept) T-cells IV
  • Auspitz sign (), Koebner reaction ()
  • Pustular psoriasis tx systemic retinoids
  • Transmitted genetically
  • Develop at sight of trauma
  • Winter worse, 1-3 population
  • Triggers strep / stress / Alcohol / Physical
    Trauma (Koebner Rxn)

24
Psoriasis
  • Types
  • Guttate
  • Drop like lesions after strep infection
  • Localized polymoplanar pustulosis
  • Erythordermic
  • Psomatic arthritis
  • Dx KOH
  • Poor self image 30 get arthiritis
  • Topical creams make sure get under scaly skin
  • Tachofolaxes atrophy, thinning of skin d/t long
    term less potentcy
  • Underlying Cause T-cells mediators with TNF

25
Koebner Rxn
  • Psorasis
  • Lichem planus
  • Lichen nitidus

26
Molluscum contagiousum
  • Umbilicated papules dome shaped pink waxy
  • Exhaggerated with ethyl-chloride
  • Auto inoculation around the eyes
  • Facial lesions in kids
  • Poxvirus
  • Sexual transmitted
  • Spontaneously resolve except immunocompromised
  • More common males
  • NO significant skin symptoms
  • Histo cup-like hyperplasia of epidermal cells
    homogeneous ellipsoid inclusions
  • Usually self-limiting
  • Tx aldara

27
Erythema multiforme
  • Herpes simplex episode multiple target lesions
    (palms soles)
  • Result of hypersensitivity reaction to infection
    or medications
  • Target lesions central necrosis perivenular
    inflammation concentric rings with vesicles in
    center uticarial plaques
  • Lesions on soles/palms
  • Prodrome HSV outbreak
  • Severe Steven Johnson Syndrome
  • Even more severe Toxic Epidermal Necrolysis
    (TEN)

28
Measles (rubeola)
  • Diffuse erythematous maculopapular rash face
    and trunk
  • Fever, lethargic, viral ezanthemas
  • Koplik spots- mouth
  • Conjunctivitis (photophobia)

29
Bullous impetigo contagiosa
  • Honey-crusted
  • Staphylococcus aureus
  • Nonbullous impetigo B-hemolytic strep

30
erysipelas
  • St Anthonys fire
  • Acute cellulitis
  • Prodrome N/v, headache, fever, chills (24-48h)

31
Onychomycosis
  • Fungus of nail
  • Types
  • Superficial white
  • Proximal subungual
  • PATHOGNUMONIC for HIV
  • Distal subungal
  • MOST COMMON

32
furuncle
  • Abscess
  • Boil
  • Collection of pus
  • Hair bearing area
  • () scarring
  • Pt is usually afebrile
  • Tx ID

33
Staph Scalded Skin Syndrome (SSSS)
  • Ritters Disease
  • () Nikolskys sign

34
Nikolskys sign
  • ()
  • SSSS
  • Toxic Epidermal Necrolysis (TEN)
  • Plemphigus Vulgaris
  • (-)
  • Bullous pemphigoid

35
Erythema infectiousum/ 5ths disease
  • Malar rash on cheeks and arms leaves reticulated
    pattern
  • parvovirus

36
Hand, foot and mouth disease
  • Rash on hands, feet and mouth
  • Low grade fever, arthralgia
  • Coxsackie virus
  • () Tzanck

37
Herpes simplex
  • Small blisters on erythematous base (above lip)
  • Tingling sensation overlying the area
  • Recurrent episodes
  • Oral acyclovir
  • Cluster pustules / vesicles on eryth. Base
  • Tzanck smear
  • Giemsa Stain
  • Giant multinucleated cells

38
HZV
  • Assoc with cancer and HIV
  • HZ opthalimucius
  • () Hutchinsons sign
  • Lesion _at_ tip of nose
  • Ramsey-Hunt syndrome
  • CN V and CN VIII
  • Ear and ear problems
  • Bells palsy

39
Varicella
  • DDx small pox
  • Varicella lesions all different stages all over
    body that move from the central to the periphery

40
Warts / Verrucae / HPV
  • Verruca Vulgaris
  • Black dots, common wart
  • MCC kids
  • Crusted lesion
  • Filiform
  • Singl soft
  • Comlication esophogeal cancer
  • Tx imiquimod (aldara)
  • Parvovirus (5ths disease)
  • Aplastic crises and anemia

41
ORF
  • Sheep pox
  • Swelling fever pain lymphadenitis
  • Eryth. With halo

42
Roseola infantum
  • Hepres virus

43
scabies
  • Sever pruritus _at_ night
  • Papular lesions interdigitally hands and feet w/
    linear burrow
  • DOC elamite

44
Cutaneous Larva Migrans(Creeping Eruptions)
  • anklystoma brasiliensis
  • Walking barefoot
  • Squiggly movement under skin

45
Erythrasma
  • Woods light coral red fluorescence
  • Caused by corynebacterium minutissimum

46
Acne
  • Starts early in males on nose as micro-comedones
  • Monobezone (benoquin) causes propionibacterium
    acnes proliferation
  • Treatment topical- clindamycin
  • Stages 1 -open/closed comedomes
  • 2- papules/pustules
  • 3- nodules / cysts
  • 4- scars
  • Male female
  • Inflamm disease
  • MCC microcomodones

47
Acne vulgaris
  • Nodules and cyst on face and chest
  • Treat w/ accutane (is a retinoid)

48
Acne keloidalis
  • Hard nodules and papules, discrete and confluent
    associated with hair loss in same area

49
Acne conglobata
  • Severe widespread, cicatrices (scars), drainning
    sinuses and polyporous comedones

50
Rosacea
  • Severe flushing of face flushers and blushers
  • increase reactivity of capillaries to heat
  • telangiectasia
  • Inflamed papules and pustules
  • Coffee
  • Tx tetracycline, sunscreens,, clindamycin green
    based cosmetic foundations
  • Not tx red wine intake

51
Hair cycle
  • Agagen hair cycle growth phase lasts 3-4 years

52
Alopecia Areata
  • Oval /round patches of hair loss
  • Spontaneously returns
  • Family hz
  • Exclamation point hairs
  • Associated dz hashimotos dz, addisons dz,
    vitiligo, hypOparathyroidism
  • Alopecia
  • No new hair after birth
  • Follicular plugging DISCOID LUPUS
  • Moth-eaten hair loss SYPHILIS
  • Trichofillomania
  • Kids pulling out own hair

53
Traction alopecia
  • Braided hair
  • Thinning and sparse hairs

54
Hot comb alopecia
  • Depigmentation and hyperpigmentation and scarring
    alopecia vertex of scalp

55
Telogen effluvium
  • Large loss of scalp hair (clumps or most)
  • Pulled out w/ little pressure
  • Pervious serious infection (febrile)

56
Sclerosis progressive systemic
  • Aka scleroderma
  • Prognosis not by Raynaunds Phenomenon
  • Most common feature is Raynauds phenomenon

57
Tuberous sclerosis
  • Ash-leaf macules, periungual fibromas, shagreen
    patch, adenoma sebaceum
  • Seizure risk
  • Flat red discoloartion of right anterior and
    lateral forehead involves the eylids and tip of
    nose on the same side

58
Seizures
  • At risk ash-leaf spots, shagreen patches,
    and adenoma sebaceum

59
Toxic epidermal necrolysis (TEN)
  • Due to drug reaction
  • () Nikolsky sign
  • Life threatening
  • Moist large raw areas crusts then detachment of
    skin
  • PLEMPHIGUS VULGARIS

60
Bullous hemorragic cellulitis
  • Mediated Tumor necrosis factor alpha

61
Acrodermatitis enteropathica
  • Serum zinc level
  • Failure to thrive
  • Malodorous pale, bulky stools
  • Hair loss

62
Sarcoptes scabiei
  • Circumscribed alopecia w/ vesicles
  • Hyphae and spores

63
Tinea cruris
  • Sites groin, thighs, butt, pubic region
  • Not scrotum and penis
  • Groin NOT genitals

64
Tinea Manuum
  • Dorsum of hand looks like ringworm
  • Palmar hand increase creases
  • 2-feet-1-hand syndrome
  • () dermatophytid RXN
  • DDx granuloma annularia
  • (-) KOH
  • (-) pruritis

65
Tinea Pedis
  • MCC dermatophytosis
  • Patterns
  • Interdigital
  • Moccasin
  • Acute vesicular
  • ()dermatopytid RXN

66
Miliaria rubra
  • Beach
  • Erythematous papulopustular rash on face, neck
    and extremities

67
Hemangioma
  • Soft, raised strawberry colored lesion
  • Appeared after birth and has enlarged

68
Candidial diaper dermatitis
  • Diaper rash- erythema of pernineal region
  • creased of butt and proximal thighs
  • Satellite papules peripherally

69
Candidal intertrigo
  • Ddx psoriasis, eczema, bacterial folliculitis,
    seborrheic dermatitis
  • not herpetic eruption

70
Miliaria crystalina
  • Diffuse scaly rash scalp and eyebrows

71
Granulation tissues
  • Capillaries an inflammatory cells

72
Dermatitis herpetiforms
  • A gluten-free diet
  • Immnofluorescence IgA dermal papillae
  • Microabscesses at tips of dermal papillae
  • Duhrings Disease
  • Herpes-like
  • Hallmark XXXX-pruritic itchy rash
  • Assoc with HLA-BA

73
Atopic Dermatitis
  • Atopy (hayfever eczema)
  • () Fam Hx
  • Pruritic, recurrent, flexures
  • All ages (MC children)
  • Comorbid warts, virus, mollus. Contag.
  • Stages
  • Infantile 2mo-2y
  • Childhood 2y-10y
  • Adult 10y-adult (only 1 out of 3-4 of cases get
    here)
  • INCREASED IgE
  • S. aureus
  • Tx muperacin or gentamycin (nostrils)
  • HypO / hyperpigmentation inflamm with chronic
    irritation
  • Allergies nickel, neomycin (neosporin)
  • ATOPIC KERAToCONJUNctivitis chronic childhood

74
Atopic Dermatitis
  • Features
  • Dennie Morgan Fold
  • Keratosis
  • HErtoghes sign
  • Headlight Sign
  • White dermopgraph
  • Cataracts
  • NOT triple response of Lewis
  • Increase risk of
  • Staph (Karposis Varicelliform)
  • Wart eruption, Moll. Contag.

75
Cowdens dz
  • Features breast lesions, thyroid goiter, hand
    keratosis , facial papules

76
Keloids and Hypertophic scars
  • Early scars are read and firm initially
  • pruritus
  • Smooth domed surface
  • No cosmetic procedures
  • Not usually hyper-pigmented in Afican americans

77
UV hn
  • Causes cutis rhomboidalis, squamuos cell
    carinoma,, poikiloderma of Civatte
    Favre-Racouchet syndrome
  • Does not cause seborrheic keratosis

78
Favre-Racouchet Syndrome
  • Zits around around eyes in old people raccoon
    eyes
  • Nodular periorbital
  • Leads to Ca

79
Atopic dermatits
  • FHx of asthma, hayfever, or allergic rhinitis
  • Diagnosis- IgE levels
  • Infantile stage starts _at_ 2mon
  • Use cotton clothing
  • Conolized by staph. Aureous
  • Tx tacrolimus ointment

80
Tinea versicolor
  • Spaghetti and meatballs
  • Hypopigmentation
  • Commony recurs
  • Repigmentation takes months
  • Dx KOH (Spag meatballs)
  • Onset scalp
  • Tx ketoconazole

81
Tinea corporis
  • Dermatiophyte infection of body (glabrous skin)
  • Ringworm of the body
  • Scaly border, clear center that flattens as
    border advances
  • XXX contagious
  • Tx topical for 4 weeks
  • Redo KOH to confirm

82
Tinea Capitus
  • MC organism tryophyte tonsorans
  • Types
  • Seborrheic dermatitis
  • Diffuse patches
  • Hair losses luster
  • (-) KOH, need hair for Dx
  • Inflamm type KERION

83
Tinea facioli
  • Tx topical only
  • Flat scaly spots that extend peripherally

84
Tinea Barbae
  • Hair by fungi falls out
  • Hair by bacteria DOES NOT fall out
  • Tx systemic antifungals

85
Candidal balanitis
  • Ddx genital warts, psoriasis, eczema molluscum
    contagiosum
  • A yeast infection frequently found in the
    uncircumcised penis

86
Candidiasis
  • Marker for HIV
  • Oral Thrush
  • Superinfection d/t wide spectrum antibiotics
  • Dx diflucan

87
Perleche
  • Angular chelitis
  • Lip licking / drooling

88
Mycosis fungoides
  • Nodules neoplastic T-cells (nuclei cerebriform
    pattern

89
Keratoacoanthoma
  • Nodular, central keratin-filled crater
  • Fast appearance, rapid growing
  • Elderly men leads to SCC
  • Smmoth shiny lesion with telangiectasia

90
Trichotillamania
  • Oval irregular patch of hair loss frontal
    scalp, enlarging
  • broken hairs w/in patch of hair loss
  • No telogen hair roots

91
Anagen effluvium
  • Abrupt hair loss, cytotoxic drug treatment
  • Thallium can cause similar problems
  • Eventual complete regrowth

92
vehicle
  • Brings meds into contact w/ skin
  • Benefits cooling, protective, emollient,
    occlusive
  • Not subcutaneous atrophy

93
Retinoids
  • Isotretinoin- severe cystic acne
  • Moa mediated via enhanced transcription via
    receptors like thyroid/steroid super family
  • Helps reduce size of sebaceous gland
  • Etretinate (tegison) and acitrein (soritane)
    psoriasis
  • Teratogenic potential long term

94
Glucocorticoids
  • Topical Vasoconstriction, anti-proliferative,
    immunosuppression, anti-inflammatory, atrophy of
    hypertrophic scars
  • Bind DNA sequence glucocorticoid responsive
    elements
  • Activation of expression of target gene
  • Physiological responses anti-inflammatory
    response
  • MOA in psoriasis- anti-mitotic effects
  • Used to inhibit formation of prostaglandins

95
Finasteride (propecia)
  • Inhibits 5-alpha reductase controls production of
    DHT

96
Trioxsalen (trisoralen)
  • Psoralen used for re-pigmentation (vitiligo)

97
Hydroquinone
  • Inhibition of tyrosinase enzyme thus inhibiting
    melanin formation blocks oxidation of tyrosine

98
Immunoflourescence
  • Important in diagnosis of blistering disease

99
Chemical peels
  • Complications pigmentary changes, infection,
    prolonged erythema, milia
  • For pigmentary dyschromias

100
Lasers
  • Light amplification by stimulated emission of
    radiation
  • Monochromatic, highly collimated, controllable,
    coherent
  • Used for vascular disorders through selective
    thermolysis

101
sclerotherapy
  • For varicose and telangiectatic veins
  • Complications cutaneous necrosis and ulceration,
    pulmonary embolism, superficial thrombophlebitis,
    post-sclerotherampy hyperpigmentation

102
Tzanck test
  • Air-dried
  • Tzanck stain postivie for multinucleated giant
    cells tx w/ intravenous acyclovir

103
dermatomyositis
  • Management Systemic gluco-corticosteroids,
    methotrexate, plasmapheresis, rest and
    physiotherapy
  • Internal malig of older patients
  • () gorrrus papules
  • Photosensitive violacema on knuckles, face, neck,
    trunk
  • Lupus-like skin

104
Carcinoid Syndrome
  • Episodic intense flushing of face, neck and upper
    chest
  • GLUCAGONOMA SYNDROME
  • Alpha-cell tumor 80 malig
  • Looks like eczema
  • Ssx malaise, wgt loss, polyuria
  • Tx excision and topical steroids

105
Syndromes
  • Sweet Syndrome
  • Prodrome URIs
  • FM
  • Assoc with internal malig
  • Gardners Syndrome
  • Multiple epidermal cysts (scalp/face)
  • Malig intestinal polyps
  • Fibrous skin tumors
  • Pigemnted ocular fundus
  • Plapable osteomas

106
Scleredema Diabeticorium
  • Non-pitting eryth.
  • Woody feeling

107
Xanthomas
  • Palmar
  • Biliary sclerosis DM lipid accmulation
  • Striated
  • Palmar creases as yelow lines
  • Tuberous
  • Any age
  • 1 hyperLIPID/CHOLESTEROLemia

108
Discoid Lupus
  • Butterfly rash
  • Tests antinuclear antibodies
  • Scarring alopecia
  • Elevated read plaques w/ firmly-adherent scale
    (butterfly rash)
  • Procainamide- cases a lupus like syndrome
  • Systemic lupus false postive syphilis serology

109
Chronic cutaneous lupus
  • UV light precipitates attack

110
Erythema nodosum
  • Form of panniculitis (inflammation of
    subcutaneous fat), lymphohistiocytic
    infiltration, giant cells, eosinophils, NO
    vasculitis
  • Back of leg () TB
  • Self limiting
  • Deep hot painful tender 1-5cm nodules on PRE
    TIBIAL SKIN
  • Tx naproxsyn

111
Lentigo
  • Solar lentigo
  • Freckle like blotchy
  • Lentigo Maligna
  • 10-20y exposure (chronic)
  • Melanoma in situ
  • Asymm irreg border macular lesions face, neck,
    dorsal arms
  • Tx Mohs surgery
  • Lentigo Maligna Melanoma (LMM)
  • Vertical growth and metastases

112
Cutais Rhomboidal Nuchae
  • Thick tough skin leathery waxy exhaggeration of
    normal skin markings
  • Pre-ca and Ca

113
Compound nevus of spitz
  • Children mistaken histologically w/ malignant
    melanoma
  • Spitz nevus spindle-shaped and plump epithelioid
    cells w/ irregularities

114
Dysplastic nevi
  • Multiple members of the family may be affected

115
Post op fever
  • Look to water, wound, walk, wind

116
Erythema toxicum neonatorum
  • 1st 3 days of life, resolves 2 weeks
  • Firm yellow papule, irregular red base, no
    therapy needed
  • Eosinophils present

117
Mal perforans ulcer
  • Pts. w/ diabets or leprosy, distal extremites

118
Eczama herpeticum
  • Multiple crops of vesicles over much of the body

119
Rhus dermatitis
  • Linear eczematious streaks

120
Syphilis
  • Secondary syphilis coin- shaped lesion
  • Annular, concentric, arcuate coppy penny lesions
    on palms/soles/head/neck
  • Dx FTA Antibodies

121
Kerion
  • Kerion boggy tender inflamed purulent lesion on
    scalp, assoc. w/ posterior cervical adenopathy
  • Alopecia with pustules
  • Scarring perm hair loss
  • (-) KOH
  • Tx griseofulvin, itraconzole, fluconazole

122
Langerhans cell histiocytosis
  • Seborrheic-like rash w/ petechial component

123
Condyloma acuminatum
  • Papillomatous epidermal hyperplasia w/
    cytoplasmic vacuolation of superficial
    keratinocytes

124
CREST syndrome
  • sclerodactyly

125
Fibroepithelial polyp
  • Firobvascular core covered by benign squamous
    epithelium

126
Porphyria cutanea tarda
  • Photosensitivity lease to vesicles and or bullae
    may scar
  • MC porphyria
  • Rfs Alcohol
  • Tx phlebotomy (decrease iron stores)
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