Collagen TXA2

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Targets for antiplatelet therapies
ADP
PDE
ADP
?cAMP
PAR-1
CollagenTXA2
Activation
COX
TXA2
GP IIb/IIIa
(Fibrinogen receptor)
Courtesy of BM Scirica, MD.Adapted from Schafer
AI.Am J Med. 1996101199-209.
cAMP cyclic adenosine monophosphate, COX
cyclooxygenase, PAR protease-activated
receptor, PDE phosphodiesterase
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