Riboswitches PowerPoint PPT Presentations

a sequence of RNA that, through its secondary and tertiary structure, ... New role of bioinformatics. Possibilities. Articles. Winkler WC. (2005) Winkler WC et al. ...

Gene regulation by riboswitches 1. Regulation of gene expression 2. Principles and examples of RNA-mediated genetic control 3. Riboswitches: - Organization and properties

5' UTR regions of riboflavin genes from various bacteria. Conserved secondary structure of the RFN-element ... Dashes and stars: obligatory and facultative base pairs ...

Found only in the Bacillus/Clostridium group; ... ylmB from Bacilli belongs to the ArgE/dapE/ACY1/CPG2/yscS family of metallopeptidases; ...

Ben Sauerwine (Carnegie Mellon, Physics) 'Central Dogma' of Molecular Biology. DNA ... First passage time for escape from metastable state (Ben Sauerwine, short talk) ...

Riboswitches Control Fundamental Biochemical Pathways in Bacillus subtilis and Other Bacteria

Biological Application: RNAs Research Focus: Searching for Novel Riboswitches in Newly Sequenced Genomes Danny Barash Department of Computer Science

alphas: SAM-II. Geobacter: S-box. proteobacteria. Need more genomes. Riboswitches in metagenomes ... SAM-II (alpha), SAM-III (Streptococci) ...

Title: Riboswitches: the oldest regulatory system? Author: test Last modified by: Gelfand Created Date: 10/1/2003 5:30:17 PM Document presentation format

Dept Genetics & Genomics, BU Sch of Med Tel. (617) 414 1654 ... RNAi machinery (genome censor; protection from viruses) microRNAs. RNA-only genes. riboswitches ...

Aptamer is a term derived from the Latin aptus - fit, and the Greek meros – part. Aptamers are oligonucleic acid or peptide molecules that bind to a specific target molecule. By selecting from a large random sequence pool, we usually can get aptamers, but natural aptamers also are found in riboswitches. To narrow down, aptamers can be classified as: DNA or RNA or XNA aptamers. They consist of (usually short) strands of oligonucleotides. Peptide aptamers. They consist of a short variable peptide domain, attached at both ends to a protein scaffold.

Aptamer is a term derived from the Latin aptus - fit, and the Greek meros – part. Aptamers are oligonucleic acid or peptide molecules that bind to a specific target molecule. By selecting from a large random sequence pool, we usually can get aptamers, but natural aptamers also are found in riboswitches. To narrow down, aptamers can be classified as: DNA or RNA or XNA aptamers. They consist of (usually short) strands of oligonucleotides. Peptide aptamers. They consist of a short variable peptide domain, attached at both ends to a protein scaffold.

Typically the new mRNA codes for a biosynthetic or transport ... Many more conserved RNA motifs are currently under investigation. Riboswitch Gene Regulation ...

telomerase RNA (telomerase maintenance) siRNA (RNA silencing) ... CRP/cAMP (68) MicF. 93. Anti-ompF. SoxR/S (22) MicC. 108. Anti-ompC. Inverse to MicF (19, 19a) ...

Functional RNA Introduction

Figure by Wade C. Winkler, Smadar Cohen-Chalamish, and Ronald R. Breaker, 'An ... Are biological terminator hairpins selected for efficiency in their folding pathways? ...

Tryptophan Biosynthesis. Translational Control. RBS strength. Mechanisms that ... Low Tryptophan Levels: Slow translation of leader peptide from Domain 1 ...

Z klady biochemie KBC / BCH Kontrola genov exprese

Z klady biochemie KBC/BCH Kontrola genov exprese

4th Bertinoro Computational Biology (BCB) Meeting ' ... Strepto-coccus spp. Lacto-bacillus spp. Clostridium spp. Trp-T-boxes TRAP. Tyr-T-boxes PCE ...

About OMICS Group OMICS Group International is an amalgamation of Open Access publications and worldwide international science conferences and events.

The metabolic map, the bird's view. Metabolic pathways, the eagle's view ... Identification of the candidate regulator by the analysis of phyletic patterns ...

Thanks to in silico analysis and genome sequencing. How to ... development in xenopus. Bicoid: anteroposterior. axis in drosophila) Cap-independent inhibition ...

Results - Ligand recognition and pH dependence. Conclusions and future structural analyses ... Clare Boothe Luce Program of the Henry Luce Foundation ...

Nat Rev Mol Cell Biol. 2005 May;6(5):376-85 microRNA Mattick, J.S. (2004) The hidden genetic program of complex organisms. Scientific American 291 (4): 60-67.

Title: Diapositiva 1 Author: Utente Last modified by: Utente Created Date: 11/15/2006 9:42:50 AM Document presentation format: Presentazione su schermo (4:3)

ILE: ilv operon (B. cereus) LEU: leuA (C. thermocellum) ... TRP: trp operon (T. tengcongensis) PHE: arpLA-pheA (D. reducens, S. wolfei) ...

an expression platform for gene regulation. A metabolite-binding aptamer domain and Riboswitch Functions U U U U U X 3 4 2 1 Direct (protein-free ...

Microbial Genetics

CAP has two binding sites, one interacts with the CAP site on the DNA near ... Different factors binding to the same RNAP, conferring each of them a new ...

Ryan. VanYperen. Lejdja. Beshku. Joanna. Ryther. Matt. Crook. Rebecca ... Franklin, Rosalind (1920-1958) Hershey, Alfred (1908-1997) Jacob, Francios (b. 1920) ...

1Dairy Microbiology, 2Dairy Cattle Nutrition, ... National Dairy Research Institute, Karnal 132001, Haryana, 3 Meerut Institute of Engineering and Technology, ...

'De novo DNA methylation in mammals: As easy as A, B, L' 26.1 DNA ... Actinomycin D inhibition of prokaryotic and eukaryotic RNA Polymerases. 26.2 RNA processing ...

Measuring kinetics of proteins. Degradation tags to inhibit the fluorescence of the proteins ... Kinetics of proteins /- LVA. Our Intermediate Constructs. Step ...

Microbot drug delivery involves attaching drugs to the exterior of microscopic ... SEM micrograph of Escherichia coli. Vesicular Somatitis Virus. Highly Specific ...

Welcome Each of You to My Molecular Biology Class. 2 ... Sporulation in Bacillus subtilis. Bacteriophage sfactors. 51. Heat shock (???) ...

Title: Inquiry into Life Twelfth Edition Author: Administrator Last modified by: Horng Created Date: 8/8/2006 9:50:44 PM Document presentation format

Microbiology: A Systems Approach, 2nd ed. Chapter 12: Drugs, Microbes, Host The Elements of Chemotherapy Figure 12.16 12.5 Considerations in Selecting an ...

M. Firdaus Raih Room 1166, Bangunan Sains Biologi Office Hours: Wednesdays Phone: 0389215961 Email: firdaus@mfrlab.org Ver. 23-01-09-1 STBC2023 Introduction to ...

Comparative genomics and metabolic reconstruction of bacterial genomes ... Winkler et al., 2002a ... Winkler et al., 2002b; Mironov et al., 2000 ...

Alternative sigma factors. In certain circumstances, bacteria shut down normal gene ... Alternative sigma factors bind to core RNA pol and direct it to ...

Title: PowerPoint Author: Shuchang Lu Last modified by: user Created Date: 7/28/2000 3:45:42 AM Document presentation format: (4:3)

Title: Comparative genomic analysis of T-box regulation: identification of new structural classes and reconstruction of evolution Author: Gelfand

Operator. Open reading frame. mRNA. Bacteria Must Regulate Gene Expression ... Synthesis of glucosamine-6-phosphate is essential for survival in many bacteria ...

IX: DNA Function: Protein Synthesis

... 1957 Illustration humoristique des cours par une s rie de dessins de F. Lavall L gendes de Georges Cohen * Figure: ...

HTC in Research & Education

25 Years of Ribozymes

osmY inverter. Regulating the timing of expression. Design principles ... Use of constitutive promoters, inducible promoters, and inverters. Berkeley 2006 ...

about whatever man builds, that all of man's ... met-tRNA formylation. Mfl409, Mfl569. Mfl152, Mfl153, Mfl154. Mfl233, Mfl234, Mfl235 ...

We must combine our understanding of mutation and recombination with comparisons ... including those for endorphins and a sialic acid receptor, and genes involved in ...

It is difficult to predict specificity by sequence analysis ... (Winkler et al., 2003) Biotin transporter BioY. Identification: co-localization. co-regulation ...

Some other sRNAs are known to repress translation intead of activating ... Binding of TPP represses translation of mRNAs that encode enzymes involved in TPP synthesis ...

To establish specific cell-to-cell communication between two populations of bacteria ... Dr. Laura Frost: F-Plasmid. Philip Silverman: pox38 F-Plasmid ...

Question: Which process stimulates sporulation? a. dephosphorylation of CheY ... How many sigma factors are involved in sporulation? a. 1. b. 2. c. 3. d. more ...