Quinolones PowerPoint PPT Presentations

Quinolones Drugs: norfloxacin, ciprofloxacin, ofloxacin, levofloxacin, moxifloxacin Mechanism of action: Inhibit bacterial DNA synthesis by inhibiting DNA gyrase and ...

Title: Author: jsj Created Date: 9/4/2003 5:40:24 AM Document presentation format: Company: ssmu Other titles

Evgenii S.Severin Russian Research Center for Molecular Diagnostics and Therapy RCMDT MOLECULAR PHYSIOLOGY INSIGHT IN OVERCOMING MULTIDRUG RESISTANCE

MECHANISM In gram- bacteria, DNA gyrase is the primary target. In gram + bacteria, topoisomerase IV is the primary target (newer quinolones). PHARMACOKINETICS Rapidly ...

Synthetic compounds consisted of an N1 alkylated 1,4-dihydro-4-oxo-3 ... action of nalidixic acid and its congener is the result of the inhibition of DNA synthesis. ...

Spontaneous withdrawal of Grepafloxacin (Raxar) by Glaxo (11/99) ... if you develop heart palpitations (fast beating), or have fainting spells. ...

Title: Quinolones Subject: Quinolones Author: Sylvestre Tigaud & Jacqueline Grando Keywords: Quinolones Last modified by: Sylvestre Tigaud Created Date

Global urinary tract infection treatment market size is expected to reach $11.74 Bn by 2028 at a rate of 2.9%, segmented as by drug class, penicillin and combinations, quinolones, cephalosporin, aminoglycoside antibiotics, sulphonamides

Title: Sulfonamides,Trimethoprim and Quinolones Last modified by: Sushike Created Date: 5/26/2003 11:39:43 PM Document presentation format ...

Inhibit bacterial gyrase ... bacterial diarrhoea caused by shigella, salmonella and E. coli Mechanisms of bacterial resistance to quinolones: ...

(University of Auckland) Nitroimidazole PA-824 (Chiron/Novartis) ... (University of Auckland/University of Chicago) Quinolones (KRICT/Yonsei University) ...

Impact of Quick Order Sets Guidance of Quinolone Use on Patient Safety ... doxycycline (less expensive) over quinolones (more expensive) ...

Broad Spectrum Antibiotic (BSA) Duration of antibiotic use. PPIs ... Clindamycin. Augmentin. Cephalosporins. Quinolones. Recent Changes...e.g. at the PRUH ...

Introductions in the United States. Selected Quinolones and Year of Introduction ... Avoids beta-lactam and sulfa allergies Some allergy potential ...

Antibiotics Inhibition of DNA synthesis Resistance to Quinolones Is due primarily to chromosomal mutations that modify the bacterial DNA gyrase.

2002 Guidelines for the Use of Antimicrobial Agents in Neutropenic Patients with ... TMP-SMZ or quinolones for routine use of all afebrile neutropenic patients. ...

Title: Quinolones in Lower Respiratory Tract Infections Author: eg050006 Last modified by: Sherif Created Date: 1/6/2004 7:33:40 PM Document presentation format

mergence des r sistances aux quinolones chez Salmonella typhimurium DT104 en GB la ... Obtenir une gu rison clinique sans effets adverses. Enjeux de sant publique. viter le ...

15 me Conf rence de Consensus en Th rapeutique Anti-infectieuse, ... Mortalit de 33% en s ries s v res en utilisant une th rapie de macrolides anciens quinolones anciennes ...

The increasing prevalence of urinary tract infection (UTI) and growth in the number of prescription of quinolones antibiotics is expected to fuel the growth of the urinary tract infection treatment market. According to a new study published by Future Market Insights (FMI), the global urinary tract infection treatment market revenues will grow at a mere 2% CAGR between 2019 and 2029.

Global market for urinary tract infection treatment is likely to expand at a sluggish rate during the next decade. FMI’s study projects a 2% CAGR for UTI treatment market revenues between 2019 and 2029. Quinolones are expected to remain highly preferred antibiotics in urinary tract infection treatment. Rising use of urinary catheters and other drainage devices likely to offer an uptick to UTI treatment market growth.

Macrolides et apparent s/pays. Gossens. Lancet 2005;365:579-87. DDJ pour 1000 habitants ... J01F : Macrolides, et apparent s. J01G : Aminosides. J01M : Quinolones ...

The report on Antibacterial Drugs Market by drug class (quinolones, tetracycline, sulfonamide, b – lactams, macrolides, aminoglycoside, phenicols), routes of administration (parenteral, enteral), distribution channel (drug stores and retail pharmacies, hospital pharmacies, online sales) trends analysis and forecasts up to 2023 studies the market sizes, key trends and opportunities in the main geographies such as North America, Europe, Asia-Pacific, Rest of the World. According to the report the Global Antibacterial Drugs Market is projected to grow at a CAGR of 4.1% in terms of value over the period of 2017-2023. The growth in the world market is primarily driven by significant contribution by North America (Leading region) region to this market.

This report covers the present scenario and the growth prospects of the Global Antibiotics market for the period 2014-2018. To calculate the market size, the report considers the revenue generated from the sales of various antibiotics for human use. The Global Antibiotics market can be divided into eight segments: Beta-lactams, Macrolides, Aminoglycosides, Phenicols, Quinolones, Sulfonamides, Tetracyclines, and Others.

AMDA and ASCP summarised top 10 danferous drug interactions involving Warfarin, ACE inhibitors, Digoxin or Theophylline with other drugs

Overview of Antimicrobials Dr W.D. Colby Microbiology & Immunology Classes of Antimicrobials -lactams Aminoglycosides Extended macrolide family Glycopeptides ...

Gram-positive bacteria: Staphylococci Staphylococcus aureus Staphylococcus aureus http://www.visualdxhealth.com/pdfs/MRSA%20Handout.pdf Superantigens http://highered ...

Urinary Tract Infection (UTI) Treatment Market: Sustained Use of Urinary Catheters Offering the Necessary Push: Global Industry Analysis 2014-2018 and Opportunity Assessment 2019-2029

... 1pyrrolidino, or similar basic moiety at 7-position appear to ... piperidino, 3-amino-1pyrrolidino, or similar basic moiety. CNS side effects. Amino group ...

in Canadian Retail Pharmacy. Source: Canadian Compuscript Audit ... Estimated Prescriptions Dispensed by Month in Canadian Retail Pharmacy ...

Antibiotic Prescribing Trends in Canada. 2002. Source: ... Anti-biotics: Oral Solid vs. Oral Liquid Formats. Estimated Prescriptions Dispensed by Month in ...

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OPHTHALOMOLGY OTIC PREPARATIONS Gerianne R. Bliss, M.D. Chuck Hensley, R.Ph. Ophthalmology General Rules: Don t prescribe steroid preparations unless asked to by an ...

Cephalosporins Base molecule is 7-aminocephalosporanic acid produced by a Sardinian sewer mold R groups determine spectrum of activity and pharmacological ...

MarA and SoxS (E.coli) Transcriptional regulation. Direct or indirect ... MarA and SoxS can both be overexpressed in a quinolone-resistant strain. CONCLUSIONS ...

some antibiotics, indicated by. inhibition of bacterial growth around ... Antibiotic use (tons) Percentage resistant fecal strains. Gentamicin. Nalidixic acid ...

Chemistry MIP Effect on microbes - MIP Spectrum of coverage Mechanism(s) of action Mechanism(s) of resistance Pharmacology of antibiotic class mostly new info

Title: Pr sentation PowerPoint Author: CHU de Rouen Last modified by: CHU de Rouen Created Date: 5/26/2005 12:22:39 PM Document presentation format

Inhibition of topoisomerases a family of enzymes responsible for maintaining ... Torsades de pointe: paroxysm of ventricular tachycardia in which the ...

Director of Infection Control, Shrewsbury and Telford NHS Trust: ... Worcester. Hereford. 4. If you do not look you will not find ! ...

Chapter 42 Tetracyclines and Chloramphenicol

Community-acquired or nosocomial infections. Infections related to foreign-body devices ... In 9% due to nosocomial infections. In 6% as prophylaxis. The point ...

Many of the principles of TB treatment were evolved from research at TRC, Chennai ... (341 patients with drug susceptible TB) Ind J Tub 2002: 49: 27-38. Daily ...

Title: IS BROAD SPECTRUM MONOTHERAPY ANTIBIOTIC TREATMENT ADEQUATE FOR INTRAABDOMINAL INFECTIONS ? Author: MUHC Last modified by: MUHC Created Date

At least 4000 years ? From cattle when they were domesticated. Rene ... for thrice-weekly ... TRC with 4-month thrice-weekly ofloxacin, gatifloxacin or ...

Title: ATB-G n ralit s Subject: ATB-G n ralit s Author: Sylvestre Tigaud & Jacqueline Grando Keywords: Antibiotique G n ralit Last modified by

NNT (otitis media) = 71 NNT (quinsy) = 50. 0.18 0.41. 0.27. Rheumatic fever. 0.07 0.35 ... Quinsy. 0.11 0.43. 0.22. Otitis media. 95% CI. Odds ratio ...

Aminoglycosides Intro Group of antibiotics used in the treatment of bacteria infections aerobic G-ve Consists of 2 or more amino sugars and a hexose nucleus Serious ...

Emory University School of Medicine, Atlanta, GA1; Fundaci n Universitaria de ... de Occidente de Kennedy2; Cl nica de Occidente2; Hospital Sim n Bol var, Bogot , ...

Victor Lim International Medical University Kuala Lumpur, Malaysia Antibiotics One of the most commonly used group of drugs In USA 23 million kg used annually; 50% ...

1st antenatal visit-urine culture. Not dipstick. Culture ve -confirm and treat. Repeat urine culture at each antenatal visit. Culture -ve not for rpt cultures ...

Ant-Infective Drugs Antibacterials Sulfa Drugs Urinary Anti-tuberculosis Antifungals Antivirals

LOWER RESPIRATORY TRACT INFECTIONS Prof T Rogers PNEUMONIA THE IMPORTANCE OF PNEUMONIA A major killer in both developed and developing countries Accounts for more ...

Bacteria in perineal area ascends through the urethra, enters the urinary ... Kidney stones. Vesicoureteral reflux. People with indwelling urinary catheters ...

Antibiotics F.A. Fehintola Introduction Selective toxicity: Basic principle of chemotherapy Seeks to exploit certain characteristics peculiar to organisms or cell ...

Intellectual Property Rights Protection in Developing Countries: The Case of Pharmaceuticals. Marshall Lecture European Economic Association Congress, Barcelona