Proteinases PowerPoint PPT Presentations

Tsetse fly (Glossinia morsitans) has a digestive carboxypeptidase with predicted ... residues for carboxypeptidases from H. armigera, Drosophila and tsetse fly ...

Plant proteinase inhibitors (PIs) are a well-established mechanism of ... Silkworm a-amylase. Y K N P Y Y A P G R(S)V N V N . Y K N P H Y A S G R T T M V H . A ...

Proteases, proteinases, peptidases or proteolytic enzymes are all common names ... They have been implicated as key factors in the pathogenesis of various diseases. ...

Cathepsin L1 (Cathepsin L or Major Excreted Protein or CTSL or EC 3.4.22.15) - Cathepsin L, a lysosomal endopeptidase is a member of the papain-like family of cysteine proteinases. Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation. Although commonly recognized as a lysosomal protease, cathepsin L is also secreted. The cathepsin L gene is activated by a variety of growth factors, tumor promoters, and second messengers. Cathepsin L promote tumor cell invasion and metastasis by catalyzing degradation of the interstitial matrix and basement membranes, thus allowing cancer cells to invade locally and metastasize to distant sites.

( thrombin fibrinogen fibrin clot ) Garbisa 2001. 0. 25. 50. 75. 100 % enzymatic activity ... preserving cathepsin G- or uPA-mediated reactions (Kang 99) ...

St John's College, Oxford, UK. For an application pack (available early ... Chris Southan. Gemini Genomics, UK. b-Secretase modelled on human pepsin template ...

Rowan Vilar e Vitor Nunes PATOGENIA DA DOEN AS PERIODONTAIS Biofilme O Biofilme representam o m todo preferido para muitas , sen o a maioria das bact rias.

The active site contains a Thr-Tyr dyad and a Thr-Lys-Asp triad. ... The dyad Thr catalyzes the acylation and forms a covalent intermediate, ...

Rowan Vilar e Vitor Nunes PATOGENIA DA DOEN AS PERIODONTAIS Biofilme O Biofilme representam o m todo preferido para muitas , sen o a maioria das bact rias.

Rodolfo Hernandez-Gutierrez, Leticia Avila-Gonzalez, Jaime Ortega-Lopez, ... Facultative anerobic parasite. Adhesion proteins on surface of flagella ...

Turnover - Lifespan of a protein from synthesis to degradation ... residue of the substrate (or the N terminus of the substrate) and ubiquitin ...

Title: Pr sentation PowerPoint Last modified by: St phane Blanc Document presentation format: Pr sentation l' cran Other titles: Times New Roman Arial Mod le ...

Another PDH E1a locus is found on chromosome 4: ... Single UDPTG1 gene complex on chromosome 2 has diversified by duplication only ...

Brief Overview on "Optimizing management of asthma and COPD" including importance of optimizing management, pathogenesis of asthma and COPD, exacerbations, treatment of exacerabtions, management strategies etc.

RNA-dependent RNA polymerase and incomplete daughter RNA strand drops off' ... Aphthoviruses: Foot-and-Mouth Disease Viruses (serotypes O, A, C, Asia, SAT 1-3) ...

Coloring agent: -carotene, annatto. Starter and adjunct cultures ... chicken, porcine, bovine pepsin. bacterial, fungal (Rhizomucor miehei) ...

Types of Drug Discovery Searches. Rational Reason-based. Not ... Design of Antithrombin Activators. MEDC 607 & MEDC 603. 4. Arg129. Lys125. Lys114. Arg46 ...

Palmar-plantar hyperkeratosis. CTSC gene. In humans, Cathepsin C is coded by the CTSC gene ... The syndrome of palmar-plantar hyperkeratosis and premature periodontal ...

... PAMP Pathogen recognition receptors (PRR) ex: CD14, TLRs, Nods, PRR: r cepteurs de l h te qui reconnaissent les PAMPs Par : ...

Know mediators secreted by the neutrophil ... Specific or Secondary (pink) ... rheumatoid arthritis and certain diseases of the eye like ulcerated corneas. ...

ENZYMES IN MEDICINE Diagnostic indicators the activities of many enzymes are routinely determined in plasma ( rarely in tissue biopsies) for diagnostic purposes ...

mice, rats, rabbits, dogs and ... solutions, tissue extracts, perfused cells & organs, ... 1 Siemens Sonata 1.5 T clinical scanners. 1 Siemens Trio 3T ...

Moromi Enzymology. A. oryzae and A. sojae produce good spectrum of enzymes ... Moromi Enzymology. Other enzymes. Cellulases, pectinases, hemicellulases, etc. ...

intracellular catabolism of peptides and proteins. processing of prohormones and proenzymes. penetration of normal human tissue by malignant cells and possibly ...

Cellular senescence, cancer and. aging. Buck Institute for Age Research ... Cancer cells acquire mutations that abrogate the. senescence response ...

Dental Conference - MID Periodontal Disease November 11, 2004 Destructive Periodontal Disease Dental plaque biofilm infection Ecological point of view Ecological ...

The name enzyme was suggested in 1867 by the German physiologist Wilhelm K hne ... into dextrinases, which may prevent tooth decay; and into the malfunctions (??) ...

IdeS: Candidate for Z-LVG-CHN2 Inhibition? IdeS: Group A streptococcal cysteine protease with the ... IdeS fails to cleave the synthetic substrate. Big Question ...

Title: Enzimas: como atuam ? Author: R_2 Last modified by: Celia Carlini Created Date: 4/15/2003 8:00:05 PM Document presentation format: Apresenta o na tela

Extracting and Exploiting Structural Patterns in Proteins, ... Winged helix. Beta Sheet. Zinc-finger. Prediction of DNA Binding Function using Structural Motifs ...

establishes an electric potential of -100 to -200 milliVolts across plasma membrane ... Nitrogen content drops drastically in leaves prior to abscission ...

1. Introduce an aliquot part of nutrients for cell cultivation. ... aliquot part of nutrients. Second fermenter: biosynthesis of PHA ...

Sea urchin sperm bind perpendicular. Calnet, University of Bristol. www.nature.com ... Seen in sea urchins. Cortical Granules migrate to vitelline membrane and ...

Osteoarthritis Hoveda Mufti M.D. 9/6/06 Definition Also known as degenerative joint disease or wear and tear arthritis . Progressive loss of cartilage with ...

Directed evolution is the most recent tool utilized in the creation of new and better enzymes (& other proteins) Key Messages Why adopt biotechnology?

Germtube Septoria tritici growing through stomata. Adhesion to Plant - nonspecific ... Galls - growth regulation. altered genetic control. Agrobacterium tumefaciens ...

eIF2 binds the initiator Met-tRNAiMet to the P site of the 40S ... It accumulates in reticulocytes when haeme production exceeds haeme utilization. Hemin ...

CD4-gp120 complexes are detected in infected cell lysates; ... X-ray pictures of p10 have enabled transition state. analogues to be developed. ...

Estereochemistry comprises empirical information about chemical interactions ... CHIRALITY of a-carbons. PLANARITY of peptide bonds and aromatic side chains ...

Title: IVIG Subject: IVIg Author: Yehuda & Amir Shoenfeld Last modified by: nivz Created Date: 9/30/1996 6:28:10 PM Document presentation format: 35mm Slides

Some chymosin become adsorbed onto paracasein and transferred into cheese ... Porcine, bovine, chicken pepsin. Rhizomucor miehei. Cryphonectria parasitica ...

California State University, Los Angeles ... California State University, Los Angeles. The effect of environmental conditions on morphology ...

Title: Developing a Simple Pathogenicity Model System for Candida Author: Default Last modified by: Gang Wu Created Date: 3/20/2003 11:50:54 PM Document presentation ...

By imbibition = a physical process in seeds with a permeable seed coat ... embryo = araliaceae (ginseng), papaveraceae (poppy), ranunculaceae (anemone) ...

Organization Chart Title

Julia Tait Lathrop1 and David Hammond2. 1American Red Cross ... apheresis. Specific protein reduction. Pathogens, viruses. Prion. reduction device (Macopharma) ...

Suboptimally Due to Angle and Length. COPD. Classic Description: Barrel Chest ... Active smoker (within 4 months) Unstable angina or cardiac arrhythmia ...

Today s Topics Introduction Sugar Chemistry Glucose 1-4 Links Glucose 1-6 Links Other Sugars Mash Rests Acid Rest Protein ... mineral salts like ... dry basis fine ...

Broncopneumopatia cronica ostruttiva (BPCO) COPD: old definition . airflow obstruction due to emphysema and chronic bronchitis Venn diagram illustrating the overlap ...

Atherosclerosis and Inflammation. Ross R. N Engl J Med 1999;340:115-126. ... From A Slide Atlas Atherosclerosis Progression and Regression, Parthenon Publishing, 1999 ...

Initiator tRNA attaches to start codon. Larger body of ribosome combines ... moves along one codon and next tRNA binds ... Final codon on mRNA contains ...

Tissue Repair

X-ray crystallography, NMR spectroscopy, single particle, cryo-electron microscopy. ... Similarity with Diadenosine Tetra-phosphatase fromE. ...

Progress is impeded less by ignorance than by the illusion of knowledge. ... ORCA (Octadecanoid-Responsive Catharanthus AP2/ERF-domain) transcription factors ...

Middle repetitive sequences flanking an exon may facilitate 'looping out' or ... Amyloid precursos. Collagens. Evolution of exon shuffling ...

Orthology: describes 'the evolutionary relationship between homologous genes ... Orthology is often used for the transfer of functional annotation from proteins ...