163 Nonsynonymous PPTs View free & download

Number of substitutions between two proteincoding genes PowerPoint PPT Presentation

Number of substitutions between two proteincoding genes - CCC (Pro) CCA (Pro) CAA (Gln) 1 synonymous and 1 nonsynonymous. Pathway II: CCC (Pro) CAC (His) CAA (Gln) 2 nonsynonymous. 10. Difficulties with numerator: ...

CCC (Pro) CCA (Pro) CAA (Gln) 1 synonymous and 1 nonsynonymous. Pathway II: CCC (Pro) CAC (His) CAA (Gln) 2 nonsynonymous. 10. Difficulties with numerator: ...

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Predictive methods using DNA sequences Unit 11 PowerPoint PPT Presentation

Predictive methods using DNA sequences Unit 11 - Missense type of nonsynonymous (different amino acid in the product of mutated ... COOKY. MONEY. Example of (Positional) Weight Matrix ...

Missense type of nonsynonymous (different amino acid in the product of mutated ... COOKY. MONEY. Example of (Positional) Weight Matrix ...

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Molecular Phylogentics and Molecular Evolution of the Alcohol Dehydrogenase A AdhA Gene in the Palms PowerPoint PPT Presentation

Molecular Phylogentics and Molecular Evolution of the Alcohol Dehydrogenase A AdhA Gene in the Palms - Molecular Phylogentics and Molecular Evolution of the Alcohol ... Deleterious (nonsynonymous substitution) To access selective pressure look at w = dN/dS ...

Molecular Phylogentics and Molecular Evolution of the Alcohol ... Deleterious (nonsynonymous substitution) To access selective pressure look at w = dN/dS ...

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Substitutions PowerPoint PPT Presentation

Substitutions - 1. Substitutions. In Amino Acids. Codons. models. Rate. Determinants. Nonsynonymous. Evolutionary patterns. Nucleotides ...

1. Substitutions. In Amino Acids. Codons. models. Rate. Determinants. Nonsynonymous. Evolutionary patterns. Nucleotides ...

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Molecular clocks PowerPoint PPT Presentation

Molecular clocks - Molecular clocks * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * The viroid is CChMVd.

Molecular clocks * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * The viroid is CChMVd.

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Pr - Title: Pr sentation PowerPoint Author: Fredj Tekaia Last modified by: Utilisateur de la version d' valuation de Office 2004 Created Date: 5/28/2003 8:48:40 PM

Title: Pr sentation PowerPoint Author: Fredj Tekaia Last modified by: Utilisateur de la version d' valuation de Office 2004 Created Date: 5/28/2003 8:48:40 PM

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Quiz next week PowerPoint PPT Presentation

Quiz next week - Tutorial #2 - Simon Fraser University ... Tutorial #2

Tutorial #2 - Simon Fraser University ... Tutorial #2

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Adaptive Molecular Evolution PowerPoint PPT Presentation

Adaptive Molecular Evolution - There is a constant rate of molecular evolution. ... Maximum likelihood methods incorporate models of codon evolution / bias. Transition ...

There is a constant rate of molecular evolution. ... Maximum likelihood methods incorporate models of codon evolution / bias. Transition ...

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Inference of selection pressure PowerPoint PPT Presentation

Inference of selection pressure - Comparison of a pair of sequences normally results in dN dS even if some sites ... consider multiple testing. Codeml (Yang) - uses codon substitution model ...

Comparison of a pair of sequences normally results in dN dS even if some sites ... consider multiple testing. Codeml (Yang) - uses codon substitution model ...

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Dan Graur - Rates of Nucleotide Substitution Dan Graur * * * * * * * * * * * * * * * * * * * In a comparison of 74 non-essential genes with 64 essential ones, the rate of ...

Rates of Nucleotide Substitution Dan Graur * * * * * * * * * * * * * * * * * * * In a comparison of 74 non-essential genes with 64 essential ones, the rate of ...

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Medical Resequencing PowerPoint PPT Presentation

Medical Resequencing - Wet bench tests. Medical Resequencing ... 120 Asian. Rieder et al NEJM 352: 2285-2293, 2005. VKORC1 - PGA samples (European, n = 23) ...

Wet bench tests. Medical Resequencing ... 120 Asian. Rieder et al NEJM 352: 2285-2293, 2005. VKORC1 - PGA samples (European, n = 23) ...

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Mutation, drift, and selection PowerPoint PPT Presentation

Mutation, drift, and selection - Discrete time model for change. Continuous time analytical solution. Differential equation (plus three others, one for each nt) ... (Hasegawa-Kishino-Yano) ...

Discrete time model for change. Continuous time analytical solution. Differential equation (plus three others, one for each nt) ... (Hasegawa-Kishino-Yano) ...

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The neutral theory of molecular evolution PowerPoint PPT Presentation

The neutral theory of molecular evolution - Do evolutionary biologists ever tire of debating whether selection or drift ... DNA sequencing is easy, fast, and cheap; genome projects ...

Do evolutionary biologists ever tire of debating whether selection or drift ... DNA sequencing is easy, fast, and cheap; genome projects ...

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break - The first to suggest using DNA and proteins to investigate evolutionary history. ... The only person ever to receive two unshared Nobel Prizes for Chemistry (1954) ...

The first to suggest using DNA and proteins to investigate evolutionary history. ... The only person ever to receive two unshared Nobel Prizes for Chemistry (1954) ...

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Pr - ... mutations, is that many mutations will have deleterious effects on fitness. ... 'Purifying selection' is a natural selection against deleterious mutations. ...

... mutations, is that many mutations will have deleterious effects on fitness. ... 'Purifying selection' is a natural selection against deleterious mutations. ...

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Lesson Four - Lesson Four Structure of a Gene

Lesson Four Structure of a Gene

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SNP and Variation PowerPoint PPT Presentation

SNP and Variation - SNP and Variation Ka-Lok Ng Asia University

SNP and Variation Ka-Lok Ng Asia University

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Mechanisms of Evolution - Mechanisms of Evolution

Mechanisms of Evolution

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Lab 11 :Test of Neutrality and Evidence for Selection PowerPoint PPT Presentation

Lab 11 :Test of Neutrality and Evidence for Selection - Include only a summary of the Arlequin output in your report (i.e., values of S and , as well as test statistics and p-values for the two neutrality tests).

Include only a summary of the Arlequin output in your report (i.e., values of S and , as well as test statistics and p-values for the two neutrality tests).

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Molecular and Genomic Evolution - Molecular and Genomic Evolution

Molecular and Genomic Evolution

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Genome-wide Regulatory Complexity in Yeast Promoters PowerPoint PPT Presentation

Genome-wide Regulatory Complexity in Yeast Promoters - Genome-wide Regulatory Complexity in Yeast Promoters Zhu YANG 15th Mar, 2006 Reference C. S. Chin, J. H. Chuang, & H. Li. 2005. Genome-wide regulatory complexity in ...

Genome-wide Regulatory Complexity in Yeast Promoters Zhu YANG 15th Mar, 2006 Reference C. S. Chin, J. H. Chuang, & H. Li. 2005. Genome-wide regulatory complexity in ...

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Detecting adaptive protein evolution PowerPoint PPT Presentation

Detecting adaptive protein evolution - There are two main explanations for genetic variation observed ... (abalone sperm lysin, sea urchin bindin, proteins in mammals) Miscellaneous. Acknowledgments ...

There are two main explanations for genetic variation observed ... (abalone sperm lysin, sea urchin bindin, proteins in mammals) Miscellaneous. Acknowledgments ...

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MOLECULAR ECOLOGY AND EVOLUTION PowerPoint PPT Presentation

MOLECULAR ECOLOGY AND EVOLUTION - MOLECULAR ECOLOGY AND EVOLUTION. NATURE AND SIGNIFICANCE OF ... Loris. 2. 0. 4. 2. 3. GP. 12. Rate of evolution* slow phase 0.32. ruminants (rapid phase) 3.9 ...

MOLECULAR ECOLOGY AND EVOLUTION. NATURE AND SIGNIFICANCE OF ... Loris. 2. 0. 4. 2. 3. GP. 12. Rate of evolution* slow phase 0.32. ruminants (rapid phase) 3.9 ...

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RATES OF NUCLEOTIDE SUBSTITUTION PowerPoint PPT Presentation

RATES OF NUCLEOTIDE SUBSTITUTION - RATES OF NUCLEOTIDE SUBSTITUTION rate = # substitutions per site per unit time (year or generation) Ancestral sequence Sequence 2 Sequence 1 If r = rate

RATES OF NUCLEOTIDE SUBSTITUTION rate = # substitutions per site per unit time (year or generation) Ancestral sequence Sequence 2 Sequence 1 If r = rate

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- 'What limit can be put to this power (natural selection), acting ... 26 year old man admitted with aseptic meningitis. Had unprotected anal sex on 20 Sept.1995 ...

'What limit can be put to this power (natural selection), acting ... 26 year old man admitted with aseptic meningitis. Had unprotected anal sex on 20 Sept.1995 ...

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Pattern of SNPs in MDR1,MRP1,and BCRP PowerPoint PPT Presentation

Pattern of SNPs in MDR1,MRP1,and BCRP - A putatively causative SNP, exon21Ala893Ser is reported to ... Association in MDR1 between the putative causative SNPs and the functional maker ...

A putatively causative SNP, exon21Ala893Ser is reported to ... Association in MDR1 between the putative causative SNPs and the functional maker ...

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Single Nucleotide Polymorphisms PowerPoint PPT Presentation

Single Nucleotide Polymorphisms - Types of Genetic Variations. Single Nucleotide Polymorphisms (SNP) Single ... Small variable repeats microsatellites ... Frequence Databases ...

Types of Genetic Variations. Single Nucleotide Polymorphisms (SNP) Single ... Small variable repeats microsatellites ... Frequence Databases ...

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Genomics, Proteomics, and Bioinformatics PowerPoint PPT Presentation

Genomics, Proteomics, and Bioinformatics - Title: No Slide Title Author: Jonathan Pevsner Last modified by: User Created Date: 6/20/2000 1:10:16 PM Document presentation format: On-screen Show

Title: No Slide Title Author: Jonathan Pevsner Last modified by: User Created Date: 6/20/2000 1:10:16 PM Document presentation format: On-screen Show

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The Biology and Genetic Base of Cancer. 2 (Mutation) PowerPoint PPT Presentation

The Biology and Genetic Base of Cancer. 2 (Mutation) - The Biology and Genetic Base of Cancer. 2 (Mutation) Mutation Bad .Good It is good, it is bad also!! Mutation in the long term it is essential to our existance.

The Biology and Genetic Base of Cancer. 2 (Mutation) Mutation Bad .Good It is good, it is bad also!! Mutation in the long term it is essential to our existance.

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Molecular Evolution and Phylogeny PowerPoint PPT Presentation

Molecular Evolution and Phylogeny - A team at Celera Genomics sequenced by exon-specific polymerase ... The phylum contains four classes (examples), including jellyfish, sea anemone and hydra ...

A team at Celera Genomics sequenced by exon-specific polymerase ... The phylum contains four classes (examples), including jellyfish, sea anemone and hydra ...

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Rapid Progression to AIDS in HIV Individuals with a Structural Variant of the Chemokine Receptor CX3 PowerPoint PPT Presentation

Rapid Progression to AIDS in HIV Individuals with a Structural Variant of the Chemokine Receptor CX3 - Rapid Progression to AIDS in HIV Individuals with a Structural Variant of the ... Costagliola, 3 C line Vaneensberghe, 1 Emmanuelle Genin, 4 Brigitte Autran, 1 ...

Rapid Progression to AIDS in HIV Individuals with a Structural Variant of the ... Costagliola, 3 C line Vaneensberghe, 1 Emmanuelle Genin, 4 Brigitte Autran, 1 ...

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Analytical Genomics of Dormancy in Seeds PowerPoint PPT Presentation

Analytical Genomics of Dormancy in Seeds - Department of Horticulture. Howard Hughes Medical Institute. University Honors College ... of Hiro Nonogaki. Germination Promoting Factors. RGL2. GA. Seed ...

Department of Horticulture. Howard Hughes Medical Institute. University Honors College ... of Hiro Nonogaki. Germination Promoting Factors. RGL2. GA. Seed ...

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Models of Protein Evolution PowerPoint PPT Presentation

Models of Protein Evolution - DNA (4 x 4 rate matrix) vs amino acid (20 x 20) resulting in many more ... in MrBayes), but all codon positions the same base freq and substitution matrix ...

DNA (4 x 4 rate matrix) vs amino acid (20 x 20) resulting in many more ... in MrBayes), but all codon positions the same base freq and substitution matrix ...

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Reseach Training Presentation PowerPoint PPT Presentation

Reseach Training Presentation - Patterns of genetic diversity, effects of the present and the past ... PCR: only one primer; without the step 95 C 2min for the unfoldment of templates ...

Patterns of genetic diversity, effects of the present and the past ... PCR: only one primer; without the step 95 C 2min for the unfoldment of templates ...

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Pr - ... UMR 5171 G nome, Populations, Interactions, Adaptation. Universit Montpellier 2, France. galtier@univ-montp2.fr. Atelier INSERM La Londe Les Maures Mai 2004 ...

... UMR 5171 G nome, Populations, Interactions, Adaptation. Universit Montpellier 2, France. galtier@univ-montp2.fr. Atelier INSERM La Londe Les Maures Mai 2004 ...

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Lesson Four - Terminator sequences ... Terminator: bases that provide a signal to tell the cell's machinery where to ... terminator. Lesson Five. Transcription. Transcription ...

Terminator sequences ... Terminator: bases that provide a signal to tell the cell's machinery where to ... terminator. Lesson Five. Transcription. Transcription ...

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Construction of a CD8 T cell epitope knockout live attenuated SIV vaccine for Mauritian cynomolgus m PowerPoint PPT Presentation

Construction of a CD8 T cell epitope knockout live attenuated SIV vaccine for Mauritian cynomolgus m - Support for David O'Connor's lab: NIH NIAID. NIH NCRR. International AIDS Vaccine Initiative ... Charles River Laboratories. David O'Connor. Esper Kallas ...

Support for David O'Connor's lab: NIH NIAID. NIH NCRR. International AIDS Vaccine Initiative ... Charles River Laboratories. David O'Connor. Esper Kallas ...

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Molecular Evolution with an emphasis on substitution rates PowerPoint PPT Presentation

Molecular Evolution with an emphasis on substitution rates - Molecular Evolution. with an emphasis on substitution rates. Gavin JD Smith ... 'Understanding the selective pressures that have shaped genetic variation is a ...

Molecular Evolution. with an emphasis on substitution rates. Gavin JD Smith ... 'Understanding the selective pressures that have shaped genetic variation is a ...

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FINAL EXAM: TAKEHOME PowerPoint PPT Presentation

FINAL EXAM: TAKEHOME - Compare Cancer500 and HDP. Test If Two Sources of SNP info Differ ... Compare Caucasian vs. Hispanic. Test whether a population genotypic frequency is in HWE ...

Compare Cancer500 and HDP. Test If Two Sources of SNP info Differ ... Compare Caucasian vs. Hispanic. Test whether a population genotypic frequency is in HWE ...

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SF06 Molecular Genetics Disease mechanisms PowerPoint PPT Presentation

SF06 Molecular Genetics Disease mechanisms - ... the same gene are Alleles. If you have the same allele at a locus you ... If a gene has more than two alleles at a locus the locus is considered polymorphic. ...

... the same gene are Alleles. If you have the same allele at a locus you ... If a gene has more than two alleles at a locus the locus is considered polymorphic. ...

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Molecular basis of evolution. PowerPoint PPT Presentation

Molecular basis of evolution. - Analysis of mitochondrial DNA proposes that Homo sapiens ... Human/carp. 0.216. 0.205. 0.186. Human/kangaroo. 0.134. 0.129. 0.121. Human/cow. Gamma-distance ...

Analysis of mitochondrial DNA proposes that Homo sapiens ... Human/carp. 0.216. 0.205. 0.186. Human/kangaroo. 0.134. 0.129. 0.121. Human/cow. Gamma-distance ...

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Genetic Variations PowerPoint PPT Presentation

Genetic Variations - SNP Pipeline for Haplotype Analysis and GEnbank (dbSNP) submissions. ... The solution to the haplotype phasing problem is not straightforward due to ...

SNP Pipeline for Haplotype Analysis and GEnbank (dbSNP) submissions. ... The solution to the haplotype phasing problem is not straightforward due to ...

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A Universal Trend of Amino Acid Gain and Loss in Protein Evolution PowerPoint PPT Presentation

A Universal Trend of Amino Acid Gain and Loss in Protein Evolution - A Universal Trend of Amino Acid Gain and Loss in Protein Evolution ... A Universal Trend ? No other more plausible explaination ...

A Universal Trend of Amino Acid Gain and Loss in Protein Evolution ... A Universal Trend ? No other more plausible explaination ...

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LargeScale Population Studies using Genetic Polymorphisms PowerPoint PPT Presentation

LargeScale Population Studies using Genetic Polymorphisms - Determine if SNPs in Hardy Weinberg equilibrium (HWE) 16/151 SNPs analyzed in DHS not in HWE ... Jeff Schageman. Bob Barnes. Dallas Heart Study. Helen H. Hobbs ...

Determine if SNPs in Hardy Weinberg equilibrium (HWE) 16/151 SNPs analyzed in DHS not in HWE ... Jeff Schageman. Bob Barnes. Dallas Heart Study. Helen H. Hobbs ...

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Substitution Patterns PowerPoint PPT Presentation

Substitution Patterns - r=rate of substitution (# substitutions/site/year) ... http://www.ncbi.nlm.nih.gov/Education/BLASTinfo/Orthology.html. Pseudogenes. Paralogous homology? ...

r=rate of substitution (# substitutions/site/year) ... http://www.ncbi.nlm.nih.gov/Education/BLASTinfo/Orthology.html. Pseudogenes. Paralogous homology? ...

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Understanding Gene Regulation: From Networks to Mechanisms PowerPoint PPT Presentation

Understanding Gene Regulation: From Networks to Mechanisms - Understanding Gene Regulation: From Networks to Mechanisms Daphne Koller Stanford University

Understanding Gene Regulation: From Networks to Mechanisms Daphne Koller Stanford University

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Comparative%20Genomics%20I:%20Tools%20for%20comparative%20genomics PowerPoint PPT Presentation

Comparative%20Genomics%20I:%20Tools%20for%20comparative%20genomics - Comparative Genomics I: Tools for comparative genomics Penn State Univ.: Ross Hardison, Webb Miller, Francesca Chiaromonte, Laura Elnitski, James Taylor, David King ...

Comparative Genomics I: Tools for comparative genomics Penn State Univ.: Ross Hardison, Webb Miller, Francesca Chiaromonte, Laura Elnitski, James Taylor, David King ...

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PAML (Phylogenetic Analysis by Maximum Likelihood) PowerPoint PPT Presentation

PAML (Phylogenetic Analysis by Maximum Likelihood) - PAML (Phylogenetic Analysis by Maximum Likelihood) A program ... (Human:0.1, Chimpanzee:0.2):0.8, Gorilla:0.3):0.7, Orangutan:0.4, Gibbon:0.5); Exercises: ...

PAML (Phylogenetic Analysis by Maximum Likelihood) A program ... (Human:0.1, Chimpanzee:0.2):0.8, Gorilla:0.3):0.7, Orangutan:0.4, Gibbon:0.5); Exercises: ...

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Genome-Wide Association Studies (GWAS) PowerPoint PPT Presentation

Genome-Wide Association Studies (GWAS) - ... gene Systematic screen of SNPs in an entire pathway Genomewide screen Systematic screen for all coding changes Introduction ... statistic under null ...

... gene Systematic screen of SNPs in an entire pathway Genomewide screen Systematic screen for all coding changes Introduction ... statistic under null ...

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Introduction to Computational Biology PowerPoint PPT Presentation

Introduction to Computational Biology - Kimura's two-parameter model. Molecular clock. Relative rate test. Phylogenetics ... Quantile normalization. Quality control. Data distributions. Histograms. boxplots ...

Kimura's two-parameter model. Molecular clock. Relative rate test. Phylogenetics ... Quantile normalization. Quality control. Data distributions. Histograms. boxplots ...

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Molecular Evolution and Population Genetics PowerPoint PPT Presentation

Molecular Evolution and Population Genetics - Gene pool = the complete set of genetic information in all individuals within a population ... Relative fitness measures the comparative contribution of each ...

Gene pool = the complete set of genetic information in all individuals within a population ... Relative fitness measures the comparative contribution of each ...

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Mutation - Mutations can occur in either somatic or germline cells. ... Vole. Barn swallow. mutation rate. mutation rate. fitness. fitness. 44. Spatial Distribution ...

Mutations can occur in either somatic or germline cells. ... Vole. Barn swallow. mutation rate. mutation rate. fitness. fitness. 44. Spatial Distribution ...

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Drosophila%20Population%20Genetics PowerPoint PPT Presentation

Drosophila%20Population%20Genetics - Darwin was the first person to recognize clearly that evolutionary change over ... eye-colour mutations such as cardinal can be found in natural populations) ...

Darwin was the first person to recognize clearly that evolutionary change over ... eye-colour mutations such as cardinal can be found in natural populations) ...

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Biology 331: Chapter 15 PowerPoint PPT Presentation

Biology 331: Chapter 15 - ... A codon for one amino acid is replaced by another Synonymous substitution: ... Loss of function mutations: Gain of function mutations: Less common than loss Why?

... A codon for one amino acid is replaced by another Synonymous substitution: ... Loss of function mutations: Gain of function mutations: Less common than loss Why?

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Sequence analysis course PowerPoint PPT Presentation

Sequence analysis course - PAUP Phylip by Joe ... Sequence analysis course Author: pirovano Last modified by: heringa Created Date: 11/2/2005 9:49:40 AM Document presentation format: On ...

PAUP Phylip by Joe ... Sequence analysis course Author: pirovano Last modified by: heringa Created Date: 11/2/2005 9:49:40 AM Document presentation format: On ...

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The CBSU Computational Biology Service Unit is a Cornell University bioinformatic core facility. PowerPoint PPT Presentation

The CBSU Computational Biology Service Unit is a Cornell University bioinformatic core facility. - Hardware: cbsusrv02, Dell PowerEdge 2550 2 Pentium 3 1.3GHz, 2GB RAM, 70GB HD; ... Hardware: Dell PowerEdge 4600, 2 Pentium Xeon 3.0GHz, 12GB RAM, 1.0TB HD; Dell ...

Hardware: cbsusrv02, Dell PowerEdge 2550 2 Pentium 3 1.3GHz, 2GB RAM, 70GB HD; ... Hardware: Dell PowerEdge 4600, 2 Pentium Xeon 3.0GHz, 12GB RAM, 1.0TB HD; Dell ...

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Nonsynonymous PowerPoint PPT Presentations