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Laura Gillini
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WHO / CDS / STB / TBS DOTS-Plus and the Green Light Committee. 2. Apply to the Green Light Committee. Case finding strategies (page 16) May 2003 ... – PowerPoint PPT presentation
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Title: Laura Gillini
1
Intercountry Workshop on the Management of
Chronic TB casesEastern Mediterranean Regional
Office Cairo, 6-8 May, 2003
- Laura Gillini
- APO/WHO/EMRO
World Health Organization
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Apply to the Green Light Committee
- Case finding strategies (page 16)
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Case finding strategies
- This section should describe the case finding
strategies for enrolling patients in the cohort
addressing the following items - Define the stage at which the patient receive DST
- Establish the criteria for inclusion/exclusion in
the cohort - Define the health care institutions in charge of
patients enrollment
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1 DST and diagnosis of MDR-TB
- Perform a DST for each suspected cases of MDR-TB,
specifying if for both first and second-line
drugs - Assess the time when the TB patient will receive
his/her first Drug susceptibility test (DST) for
diagnosis of MDR-TB (I.e.within one month after
being declared failures with CATII regimen or
after failure to CATI)
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2 Criteria for enrollment
- Define the type of cohort of patients to be
enrolled (I.e. retrospective, prospective) - Clearly state both Inclusion and exclusion
criteria
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Examples of inclusion criteria
- Patients with with MDR-TB confirmed by a DST and
smear positive - Patients with with MDR-TB confirmed by a DST
smear negative but culture positive - Patients who have failed category II culture
positive with a DST showing MDR-TB
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Examples of exclusion criteria
- Medical conditions preventing use of second-line
drugs (I.e.liver or renal impairment) - Patient not compliant with hospitalization or
long term DOT - Lack of effective drugs (on the basis of second
line drugs DST) - Pregnancy (unless informed consent given)
- Age (unless informed consent given)
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3 Define responsibilities
- Remember to clarify and list the institutions and
the staff in charge of the enrollment, management
and follow-up of MDR-TB patients
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