Autophagy PowerPoint PPT Presentations

10 weeks: 75% of chimpanzee liver cells contained hepatitis B viral proteins. ... Cellular markers on viral membranes were consistent with autophagosomal markers. ...

3 After 4 days of treatment no more autophagosomes, only one large punctus ... Removal of K11777 (wash out) resulted in disappearance of autolysosome after 15 ...

... Autophagy Central Vacuole Mitochondria Chloroplast (a plastid) Cytoskeleton: Microtubules Organelle Movement Centrioles / Centrisomes Flagella / Cilia ...

Autophagy and plant innate immunity Formation of the autophagosome Regulation of PCD initiated during plant innate immunity by autophagy Recent ...

Autophagy = of own cellular organelle. Heterophagy = degradation of endocytosed molecules. Lysosomes membrane contain unique lipid (lyso-biphosphatidic acid) ...

Autophagy and viability: pro-survival or pro-death? Autophagy as an antimicrobial defence mechanism Autophagy as an antimicrobial defence mechanism Compounding the ...

Autophagy= Digestion of cell s own substances. Lysosome + Autophagic vacuole = Autophagolysosome. Eg; Atrophy, Cell injury, cell remodeling. Heterophagy=

Molecular mechanism and role in cellular homeostasis

Title: Autophagy and viability: pro-survival or pro-death? Author: User Last modified by: User Created Date: 12/11/2006 2:49:06 PM Document presentation format

Preosteoblast Fully mature osteoblast FIP200 ULKs Atg13 LC3-I LC3-II conversion LC3-II Autophagosome Osteoblast differentiation Preosteoblast Fully mature ...

... (autophagy) Lysosome metamorphosis ...

... Autophagic Apoptosis and Autophagy Normal cell Membrane blebbing ...

... (autophagy) TRIGGERING * Periodic Fever Syndromes PFS PFS ...

* The Pathway of Protein Synthesis Figure 3.10 * Lysosomes Vesicles within the cytoplasm which contain ... pinocytosis or autophagy. Autophagy (self-eating) ...

The Cell: The Basic Unit of Life. Life requires a structural ... Autophagy ... where digestion of spent cellular components occurs, a process called autophagy. ...

Modelling of apoptosis and autophagy pathways. iCHIP Plattform ... Autophagy (dual role) Can protect against apoptosis during ischemic injury) ...

Excessive autophagy can result in cell death, but scientists are currently debating whether autophagy represents a distinct pathway of programmed cell death. ...

During autophagy proteins that can be spared are digested in lysosomes and ... Lysotracker is a pH sensitive probe that can detect autophagy in larval fat body ...

... a process called autophagy Concept Check Main difference between phagocytosis and autophagy? Why are prokaryotic cells so impressive when compared to eukaryotic ...

The Golgi apparatus produces lysosomes by budding. Contains digestive enzymes synthesized ... Autophagy, or autophagocytosis programmed cell death (apoptosis) ...

KFERQ: cytosolic proteins with KFERQ are selectively taken up by lysosomes in chaperone-mediated autophagy under conditions of nutritional or oxidative stress.

Bioinformatics and Evolutionary Genomics ... Why are people generating these data? ... A autophagy. B spindle pole body function. C and vesicular transport ...

Induction of inflammation and apoptosis. Autoimmunity: post-infectious sequelae. Autophagy ... Autoimmunity: post-infectious sequelae ...

... contains active hydrolytic enzymes Food vacuole fuses with lysosome Hydrolytic enzymes digest food particles LE 6-14b Autophagy: ...

compartmentalization of chemical reactions within ... autophagy(autophagosome forms) recycles own organelles. autolysis. lysosomal damage after death ...

compartmentalization of chemical reactions within ... autophagy(autophagosome forms) recycles own organelles. autolysis. lysosomal damage after death ...

Organ System group of organs functioning together. ... autophagy. renews the cell. Storage. B) Lysosomes. Contain a digestive enzyme. ...

Protein molecules are continuously synthesized and degraded in all living organisms. ... Lysosomal: Steps= Uptake (Autophagy) into lysosome: Secretory vesicles; ...

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MORT CELLULAIRE CONCEPTS ET VOIES DE MORT NECROSE APOPTOSE AUTOPHAGY NECROSE La n crose est une mort anormale de la cellule (cf. apoptose) Causes possibles : Perte ...

In presynaptic cells, secretory vesicles (synaptic vesicles) containing ... are degraded in the lysosome arrive by endocytosis, phagocytosis, or autophagy. ...

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N-glycosidic bonds form via an N-glycosidic linkage is through the amide group ... are degraded in the lysosome arrive by endocytosis, phagocytosis, or autophagy. ...

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State: Every organism is in a state or condition which changes with time. ... Enhance intracellular turnover: lysosomes & autophagy. ...

S1 BEL7402 Huh7 C Tet Rapa C Tet Rapa LC3-I LC3-II GAPDH Figure S1 Detecting Tetrandrine-induced autophagy in Huh7 and BEL7402 cell lines.

... autophagy, endocytosis * * * How it interacts with cargo What has been studied What needs to be studied * * * * * * * * * * * * * * * Strain: ...

spontaneous generation (living ... All organisms composed of cells and cell products. ... autophagy - the digestion of worn out organelles and mitochondrion ...

Summarize the role of the nucleus. List the major organelles found in the cytosol, and describe their roles. ... Autophagy: digest worn-out organelles within a cell ...

... (Autophagy) into lysosome: Secretory vesicles; Cytoplasm; Organelles, and enzymatic degradation . Non-lysosomal: Steps= Tagging of protein to be degraded ...

autophagy = receptor-mediated endocytosis. EXAMPLE: Low Density Lipoprotein (LDL) 13-35 (Alberts): Three pathways to degradation in lysosomes ...

... and Autophagy in Aging Organized by Bruce N. Ames & Jose Vina Advances in Translational Science by Micronutrients Carotenoids and Vitamin A Organized by ...

Enzymes acting at a later stage. Membrane proteins docking and fusion ... Autophagy. Residual bodies. Lipofuscin granules. Lysosomes. Topic 9-3. 13. Two categories ...

Viruses and phage- show no cell membrane, their genetic materials either DNA or ... Autophagy: degradation of intracellular components in lysosomes; heterophagy: ...

These compartments can be isolated by cell fractionation and studied ... Autophagy recycle organic material. Apoptosis programmed cell death. Figure 7.13 Lysosomes ...

DNA microarrays are used to map a global pattern of gene expression. Can compare mRNA levels of ... phagocytosis / autophagy. receptor mediated endocytosis ...

Transport from the ER through the Golgi Apparatus - continuation of the ... are degraded in the lysosome arrive by endocytosis, phagocytosis, or autophagy. ...

Regardless of how this is done, how the implicit assertions are assessed, ... autophagy, or. therapeutic agents 'Interestingness' Measures. Field of data mining. ...

CHAPTER 7. A TOUR OF THE CELL. Cytology: science/study of cells ... Autophagy: recycle cell's. own organic material. Tay-Sachs disease~ lipid digestions disorder ...

... and ARF1-GTP complex to grab MPR s that hold lysosomal enzymes Lysosomes and autophagy- we destroy old, worn-out organelles w/ lysosomes.

essential for autophagy. A_1_4. YAL008W. protein of unknown function. A_1_5. YAR062W. putative pseudogene. A_1_6. YBL087C. 60s large subunit ribosomal protein l23.e ...

... (only cancer matters) It or its effects reversible by Damage rising with age Autophagy in Alzheimer s Disease Calnexin Dystrophic Neurites IEM Cat D ...

The schematic flow diagram depicts the multiple stages at which autophagy may have a role in intestinal physiology, acute stages of inflammatory injury and the ...

The same number of cells must be removed to maintain homeostasis. This occurs by Apoptosis and/or Autophagy. Life. Death. Too Much vs. Too Little Cell Death ...

Works as the main manufacturing, shipping, and storing center of the cell ... Autophagy- lysosomes use hydrolytic enzymes to recycle cell's own organic material ...

How does cellular respiration work? What Cleans up a cell? What s autophagy Cell Wall Ribosomes How do ribosomes make protein? Cell ...