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Title: VJ


1
VJ
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The Skin Though the Microscope
3
  • Most of us think of our skin in terms of How we
    look. A healthy skin not only looks well but
    performs vital body functions more efficiently.
    The skin is basically a wrapping which protects
    the encased organism.

4
  • As early as the 16th century, men such as
    Vesalius began to recognize the importance of
    certain parts of the human body the muscles,
    bones, the heart and lungs but they failed to
    recognize the skin as an organ which performs
    vital body fuctions.

5
Even during the Italian Renaissance with its
great advances in science and the arts, there was
little knowledge of the skin. The great palaces
had no washing facilities at all.
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What is the color of the blood in the arteries?
Veins?
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  • Facts about the skinThe skin is the bodys
    largest organ, covering the entire body. In
    addition to serving as a protective shield
    against heat, light, injury, and infection, the
    skin also
  • regulates body temperature.
  • stores water and fat.
  • is a sensory organ.
  • prevents water loss.
  • prevents entry of bacteria.

13
  • Throughout the body, the skin's characteristics
    vary (i.e., thickness, color, texture). For
    instance, the head contains more hair follicles
    than anywhere else, while the soles of the feet
    contain none. In addition, the soles of the feet
    and the palms of the hands are much thicker.
  • The skin is made up of the following layers, with
    each layer performing specific functions
  • epidermis
  • dermis
  • subcutaneous fat layer
  •  
  • epidermisThe epidermis is the thin outer layer of
    the skin which consists of the following three
    parts
  • stratum corneum (horny layer)This layer consists
    of fully mature keratinocytes which contain
    fibrous proteins (keratins). The outermost layer
    is continuously shed. The stratum corneum
    prevents the entry of most foreign substances as
    well as the loss of fluid from the body.
  • keratinocytes (squamous cells)This layer, just
    beneath the stratum corneum, contains living
    keratinocytes (squamous cells), which mature and
    form the stratum corneum.
  • basal layerThe basal layer is the deepest layer
    of the epidermis, containing basal cells. Basal
    cells continually divide, forming new
    keratinocytes, replacing the old ones that are
    shed from the skins surface.
  • The epidermis also contains melanocytes, which
    are cells that produce melanin (skin pigment).
    Hair, scales, claws, hooves, fingernails, teeth
    are all part of the epidermis.

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  • dermisThe dermis is the middle layer of the skin.
    The dermis contains the following
  • blood vessels
  • lymph vessels
  • hair follicles
  • sweat glands
  • collagen bundles
  • fibroblasts
  • nerves
  • The dermis is held together by a protein called
    collagen, made by fibroblasts. This layer also
    contains pain and touch receptors.The sebaceous
    glands are responsible for the excretion of the
    skin's natural oil (sebum). There are two types
    of sweat glands. The apocrine sweat glands fail
    to open directly onto the skin surface, but drain
    into large hair follicles. They are located near
    the armpits and around the genitalia, while the
    second type, the eccrine sweat glands, are
    distributed over the skins entire surface. The
    secretion of the apocrine differs to that of the
    eccrine it is thick and creamy in contrast to
    the watery solution of the eccrine glands. These
    glands aid in the removal of dirt and oil from
    the pores, help to regulate body temperature and
    also maintain the skin's PH balance.
  • subcutisThe subcutis is the deepest layer of
    skin. The subcutis, consisting of a network of
    collagen and fat cells, helps conserve the bodys
    heat and protects the body from injury by acting
    as a "shock absorber."

15
  • The Ageing Process
  • Aging is an inevitable fact of life. No matter
    how hard we attempt to avoid or eliminate it, the
    aging process continues to gnaw away at each and
    every one of us on a daily basis. However, this
    gradual but certain fact of reality need not be
    cursed upon. To appreciate the aging process you
    must firstly gain an understanding of how we as
    humans age. After all, the skin is the largest
    organ of the body therefore we must all endeavor
    to nourish and protect it.

16
  • Why Do We Age?
  • Over the years wrinkles develop and we begin to
    notice our skin aging. These wrinkles are a
    result of damaged supporting tissue, the dermis.
    The dermis contains water, fat and cells, which
    aid in the production of two very important
    fibres, collagen and elastin. It is these
    fortifying fibres that give the skin firmness and
    elasticity. As we age, the dermis retains less
    water and fat - the skin ceases to look plump,
    fewer supporting fibres are produced - the skin
    is less resilient, oil flow slows considerably -
    the skin is drier, and tiny capillaries beneath
    the skin close off - the skin receives less
    oxygen and minimal nutrients. Cell renewal rate
    also slows, therefore the development of new
    cells takes longer, while old cells remain longer
    on the surface of the skin. The result of this
    rather simple process is, older looking skin
    showing visible creases, spots and sags.

17
  • Protecting Your Skin
  • We all need to protect and look after our skin on
    a daily basis. There are many factors that
    influence aging and the awareness of these
    factors is essential if we are to avoid or at
    least monitor them. Stress, pollution, drugs,
    alcohol, cigarette smoking, improper nutrition,
    lack of sleep and ultra violet radiation play
    havoc on our lifestyle, which in turn stresses
    the skin tremendously and causes free radicals to
    attack the body. Free radical damage contributes
    greatly to the aging process by destroying
    healthy cells and damaging tissue. Free radicals
    are molecules of oxygen with unpaired electrons
    that desperately roam the body in search of
    normal healthy cells to latch onto. Once this
    attachment process takes place, oxidation begins
    - rather like metal rusting during weather
    exposure. Oxidation occurs most readily in fats,
    therefore cell membranes rich in fat, are prime
    targets.

18
  • Sun Exposure and Heat
  • Sun exposed areas of the skin seem to show more
    wrinkles, spots, blemishes and pigment changes
    than covered areas. This aging and discoloration
    of the skin is believed to be caused by sun
    damage to the dermal connective tissue, resulting
    in the skins lose of elasticity and collagen.
    Dermal connective tissue that has been affected
    by ultra violet radiation (UVR) is not as firm or
    as resilient as normal connective tissue,
    therefore the surrounding blood vessels lack
    support. To protect your skin from the sun's
    harmful rays, slather sunscreen on all exposed
    areas whenever you step outside. Choose a
    sunscreen with a sun protection factor (SPF) of
    15 or higher, and one which blocks both UVA and
    UVB rays - a broad spectrum sunscreen. Ultra
    violet radiation can also penetrate and damage
    skin through clouds and glass, therefore remember
    to apply sunblock during winter and while
    driving. Sit in the shade whenever possible and
    avoid heat on the surface of the skin.

19
  • Smoking Drugs
  • Smoking, drugs and alcohol encourage the invasion
    of free radicals, therefore these substances must
    be avoided whenever possible. Red wine consumed
    in moderation however, can be very beneficial to
    the skin due to a good supply of grape
    antioxidants. Smoking, on the other hand,
    deprives the skin of normal blood flow and also
    interferes in the healing process following
    cosmetic surgery on the skin. A smoker's face
    tends to show more lines and wrinkles than the
    face of a non-smoker the skin may appear
    slightly gray, have a leathery or rugged
    appearance or a subtle gauntness.
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