National Institute of Biomedical Imaging and Bioengineering

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National Institute of Biomedical
Imaging and Bioengineering

• Richard E. Swaja, Ph.D.
• National Institute of Biomedical Imaging and
  Bioengineering
• BERAC April 26, 2002

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National Institutes of Health

• NCI NEI NHLBI
  NHGRI
• NIA NIAAA NIAID NIAMS
• NIBIB NICHD NIDCD NIDCR
• NIDDK NIDA NIEHS NIGMS
• NIMH NINDS NINR NLM
• FIC NCCAM NCMHD NCRR

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NIBIB History

• Mandated on December 29, 2000
• Establishment Package April 25, 2001
• First budget approved January 10, 2002
• FY2002 Budget - 112 M (45 67)
• First RFAs February (First grant April)
• Currently About 22 employees (30 in FY)
• Web site http//www.nibib.nih.gov
• Director and Advisory Committee ?

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Whats Different?

• Focus on enabling technologies with broad
  applications for disease and biological processes
• Multi-disciplinary and collaborative research
• Technology- and design-driven applications in
  addition to hypothesis-driven
• Inter-agency and Intra-NIH coordination

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Sensors

• Detector transducer actuator system
• Biological, chemical, and mechanical detectors
• Signal transduction and processing
• Actuators for therapy and intervention
• Integrated systems
• Power sources
• Biointerfaces
• Model algorithms

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Nanotechnology and Microtechnology

• BioMEMS and BioNEMS
• Nanoparticles and nanomanufacturing
• Detectors and sensors
• Cell encapsulation
• Molecular machines
• Contrast agents
• Probes
• Targeted drug delivery
• Gene transfer

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Biomaterials

• Cell-level Tissue engineering
• Organogenesis
• Bioreactors
• Scaffolds
• Stem cells
• Macro-level
• Devices
• Prosthetics
• Implants

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Computer Applications

• Modeling and simulation
• Robotics
• Computer-assisted surgery
• Signal analysis and processing
• Telemedicine

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Imaging

• Diagnostic and research (molecular/cellular)
• Contrast agents
• Multiple modalities
• Signal analysis and processing
• Data analysis and transmission
• Image-guided intervention
• Platform development
• Devices and optimization
• Biophotonics

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When to apply to the NIBIB

• Research and development of enabling technologies
  and devices
• Must have broad or multiple application to
  diseases or biological processes
• For specific disease or clinical applications,
  apply to appropriate institute
• Research must have biomedical application

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Current NIBIB BMI and BME Research Opportunities

• Bioengineering Research Grants (BRGs)
• Bioengineering Research Partnerships (BRPs)
• RFA EB-02-001 (Molecular BMI)
• RFA EB-02-002 (Sensor BME)
• Participation in other RFAs and PAs

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Participation in RFAs and PAs

• Basic technology development for diagnostic and
  molecular-level imaging (NCI)
• Functional neural imaging (NIMH)
• Non-invasive sensors (NIDDK)
• Biomaterials development (NHLBI)
• Bioterrorism (NIAID)

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Bioengineering Research Grants PA-02-011

• R01 mechanism Coordinated by BECON
• Multi-disciplinary research applicable to
  biomedical problem
• Single or small groups of investigators
• Applications due on regular R01 dates February
  1, June 1, and October 1
• 102 BRG awards Average 330 k/yr

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Bioengineering Research Partnerships PAR-02-010

• R01 mechanism BECON coordinated
• Requires multi-organizational, multi-disciplinary
  teams to conduct research
• Next deadline August 12
• 60 BRP awards - 880 k/yr
• Partner with NIH grantee

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Phased Innovation Award R21/R33

• Aimed at high-risk, innovative research
• R21 Seed money to proof-of-principle 2
  years - 100-150 k/yr.
• R33 Like R01 3 years No limit but must
  justify budget
• Check institute requirements Some require
  package, some can apply separately

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NIBIB and DOE

• Focus of NIBIB is on technology development
• NIBIB focus areas are DOE strengths
• BRG and BRP offer partnering opportunities for
  technologists (intramural)
• R21/R33 provide opportunities for innovative
  research
• Caveats and Opportunities

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www.nibib.nih.gov

• Whats New
• Contact information
• Research opportunities
• Training opportunities
• Symposia and workshops
• Calendar
• Vacancy announcements
• General information