???????(RCT): 6

1
21????, ???????(RCT) 6 ?????? 8 ?????
1 ?????? 1 ??????????
5 ???????? 10
2
SCI???????????????????????

• ??
• ?????????????
• ? ?
• ????????????????
• ???????????

3
???????????? ?????? ?? ?? (Important)
????????????(??????)
4
??????????? ?????,?????????
???? ?????,???????? ?????,?????????
???????
5
???????????? ?????? ? ? ???????????????? ?????
??????
6
??????? ????
?????????? ?? ?????(?????????)
?? ???(??????) ?????????
???? ???? ????(??)??
????
7
???? ????????(??RCT
) ? ??RCT ???(??)RCT ???????? ????????
?????(????)   ???? ?
8
???????????? ?????? ??? (Novelty)
???????????????????,???????,????????,????????????
??????
9
???(Science) ???????,????????????????
????,???????,??????,????????????????????????????
,????????????,?????????
10
??? (Applicability) ?????????(???????????????,
??????????????)
11
? ? (Information) ???????????,?????????? ???
(Ethics) ????,?????????????????,????????????
,?????????????????????????
12
?? Percutaneous Coronary Intervention versus
Coronary-Artery Bypass Grafting for Severe
Coronary Artery Disease Serruys PW, et al. N Engl
J Med 2009, 360 961 ????????????????????,?
?????(3???????)???,???????????(CABG)???????(PCI)??
???????????????12???,CABG??????????????PCI??
13
??

• ? Hou FF(???) Efficacy and Safety of Benazepril
  for Advanced Chronic Renal Insufficiency. N Engl
  J Med, 2006, 354131-140
• ??????????????????????????????????,?????????????
  ?????,?????????????,??????????????????,???????????
  ????,???110???,??3???

14
????????

• ?????????????
• ?1???????????
• ?2???????????????
• ?3????????????????
• ?????
• (?????????,??????????????????)

15
???????,??????????????????(????????????) ???????
?????????????????????? ?????,??????? ?????????????
?
16
??????????????? ??????,?????? ???????,?????????
??????????? ????? ????,?????????
17
????????????? ???????? ? ?????????????????
???????????????? ??????????????????
??????????,????? ? ??????????,??????? ?
????????????????(4?) ? ?????????????
18
???????????????? ????????? ????????? ????????????
?,???????? ?????????? ???????????????? ??
???????????????????
19
??????????????? 1??????????????,????? 2??????????
???????(2?) 3??????????????????? 4???????????,too
China-specific 5??????????,??
20
?????? ?? ????????????? ?? ???????????????

21
???????????! ? ?!